Polypyrrole - A conducting polymer for biomedical applications

Journal of the Chinese Institute of Chemical Engineers

Volumn 35, Issue 1, 2004, Pages 131-140

  Neoh, K G ^a   Kang, E T ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Biocompatibility; Biosensor; Glucose oxidase; Heparin; Polypyrrole

Indexed keywords

ADHESION; BIOMEDICAL ENGINEERING; BIOSENSORS; COPOLYMERIZATION; ELECTRIC CONDUCTANCE; ENZYMES; GLUCOSE;

ANTICOAGULANTS; CONDUCTING POLYMERS; ELECTRICAL STIMULATION; ELECTROCHEMICAL RESPONSE;

POLYMERS;

MEDICAL APPLICATION;

EID: 2142826584     PISSN: 03681653     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Behm, E., P. Ivanovich, and H. Klinkmann, "Selective and Specific Adsorbents for Medical Therapy," Int. J. Artif. Organs, 12, 1 (1989).
2. Bélanger, D., J. Nadreau, and G. Fortier, "Electrochemistry of the Polypyrrole Glucose-Oxidase Electrode,". J. Electroanal. Chem., 274, 143 (1989).
3. Bidan, G., "Electroconducting Conjugated Polymers: New Sensitive Matrices to Build up Chemical or Electrochemical Sensors," Sens. Actuators. B., 6, 45 (1992).
4. Bonde, M., H. Pontoppidan, and D. S. Pepper, "Direct Dye Binding-A Quantitative Assay for Solid-Phase Immobilized Protein," Anal. Biochem., 200, 195 (1993).
5. Byun, Y., H. A. Jacobs, and S. W. Kim, "Heparin Surface Immobilization through Hydrophilic Spacers-Thrombin and Antithrombin-III Binding Kinetics," J. Biomat. Sci.-Polym. Ed., 6, 1 (1994).
6. Caliceti, P., O. Schiavon, L. Sartore, C. Monfardini, and F. M. Veronese, "Active Site Protection of Proteolytic Enzymes by Poly(ethylene glycol) Surface Modification," J. Bioact. Compatible Polym., 8, 41 (1993).
7. Chen, Y. J., E. T. Kang, K. G. Neoh, and K. L. Tan, "Covalent Immobilization of Invertase onto the Surface-Modified Polyaniline from Graft Copolymerization with Acrylic Acid," Eur. Polym. J., 36, 2095 (2000).
8. Choi, C. S. and H. Tachikawa, "Electrochemical Behavior and Characterization of Polypyrrole-Copper Phthalocyanine Tetrasulfonate Thin Film: Cyclic Voltammetry and In situ Raman Spectroscopic Investigation," J. Am. Chem. Soc., 112, 1757 (1990).
9. Cosnier, S., "Biomolecule Immobilization on Electrode Surfaces by Entrapment or Attachment to Electrochemically Polymerized Films, A Review," Biosens. Bioelectron., 4, 443 (1999).
10. Deshpande, M. V. and D. P. Amalnerkar, "Biosensors Prepared from Electrochemically-Synthesized Conducting Polymers," Prog. Polym. Sci., 18, 623 (1993).
11. Edelman, P. G. and J. Wang, Ed., Biosensors and Chemical Sensors, American Chemical Society, Washington, D.C., U.S.A. (1992).
12. Foulds, N. C. and C. R. Lowe, "Enzyme Entrapment in Electrically Conducting Polymers," J. Chem. Soc., Faraday Trans. 1, 82, 1259 (1986).
13. Garner, B., B. Georgevich, A. J. Hodgson, L. Liu, and G. G. Wallace, "Polypyrrole-Heparin Composites as Stimulus-responsive Substrates for Endothelial Cell Growth," J. Biomed. Mater. Res., 44, 121 (1999).
14. Garnier, F. and H. K. Youssoufi, "Enzyme Recognition by Polypyrrole Functionalized with Bioactive Peptides," J. Am. Chem. Soc., 116, 8813 (1994).
15. Kang, E. T., K. G. Neoh, K. L. Tan, Y. Uyama, N. Morikawa, and Y. Ikada, "Surface Modification of Polyaniline Films by Graft Copolymerization," Macromolecules, 25, 1959 (1992).
16. Kang, I. K., B. K. Kwon, J. H. Lee, and H. B. Lee, "Immobilization of Proteins on Poly(methyl methacrylate) Films," Biomaterials, 14, 787 (1993).
17. Kang, E. T., K. G. Neoh, W. Chen, K. L. Tan, D. J. Liaw, and C. C. Huang, "Surface Structures and Adhesion Characteristics of Poly(tetrafluoroethylene) Films After Modification by Graft Copolymerization," J. Adhesion Sci. Technol., 10, 725 (1996a).
18. Kang, I. K., O. H. Kwon, Y. M. Lee, and Y. K. Sung, "Preparation and Surface Characterization of Functional Group-grafted and Heparin-Immobilized Polyurethanes Prepared by Plasma Glow Discharge," Biomaterials, 17, 841 (1996b).
19. Kim, Y. J., I. K. Kang, M. W. Huh, and S. C. Yoon, "Surface Characterization and In vitro Blood Compatibility of Poly(ethylene terephthalate) Immobilized with Insulin and/or Heparin Using Plasma Glow Discharge," Biomaterials, 21, 121 (2000).
20. Kobayashi, H. and Y. Ikada., "Covalent Immobilization of Proteins on to the Surface of Poly(vinyl alcohol) Hydrogel," Biomaterials, 12, 747 (1991).
21. Kotwal, A. and C. E. Schmidt, "Electrical Simulation Alters Protein Adsorption and Nerve Cell Interactions with Electrically Conduction Biomaterials," Biomaterials, 22, 1055 (2001).
22. Kulik, E. A., K. Kato, M. I. Ivanchenko, and Y. Ikada, "Trypsin Immobilization onto Polymer Surface through Grafted Layer and Its Reaction with Inhibitors," Biomaterials, 14, 63 (1993).
23. Lee, J. H. and I. J. Chung, "Electrical Conductivity of Stretched Polypyrrole Film," Synth. Met., 53, 245 (1993).
24. Liu, X., K. G. Neoh, L. Zhao, and E. T. Kang, "Surface Functionalization of Glass and Polymeric Substrates via Graft Copolymerization of Viologen in an Aqueous Medium," Langmuir, 18, 2914 (2002).
25. Moulder, J. F., W. F. Stickle, K. D. Bomben, and J. Chastain, Ed., Handbook of X-ray Photoelectron Spectroscopy, Perkin-Elmer Corporation, Eden Prairie, MN (1992).
26. Neoh, K. G., E. T. Kang, and K. L. Tan, "Protonation and Deprotonation Behavior of Amine Units in Polyaniline," Polymer, 34, 1630 (1993).
27. Okada, T. and Y. Ikada., "In-vitro and In-vivo Digestion of Collagen Covalently Immobilized onto the Silicone Surface," J. Biomed. Mater. Res., 26, 1569 (1992).
28. Potember, R. S., R. C. Hoffmann, H. S. Hu, J. E. Cocchiaro, C. V. Viands, R. A. Murphy, and T. O. Poehler, "Conducting Organics and Polymers for Electronic and Optical Devices," Polymer, 28, 574 (1987).
29. Sadik, O. A., "Bioaffinity Sensors Based on Conducting Polymers: A Short Review," Electroanalysis, 11, 839 (1999).
30. Schmidt, C. E., V. R. Shastri, J. P. Vacanti, and R. Langer, "Stimulation of Neurite Outgrowth Using an Electrically Conducting Polymer," Proc. Natl. Acad. Sci. U.S.A., 94, 8948 (1997).
31. Skotheim, T. A., Ed., Handbook of Conducting Polymers, Vol. 1., Marcel Dekker, New York, U.S.A. (1986).
32. Trojanowicz, M., "Enzyme Entrapped Polypyrrole Modified Electrode for Flow-Injection Determination of Glucose," Biosens. Bioelectron., 5, 149 (1990).
33. Trojanowicz, M. and M. L. Hitchman, "A Potentiometric Polypyrrole-Based Glucose Biosensor," Electronanlysis, 8, 263 (1996 ).
34. Umana, M. and J. Waller, "Protein-Modified Electrodes: The Glucose Oxidase/Polypyrrole System," Anal. Chem., 58, 2979 (1986).
35. Xu, G. C., Y. Hibino, Y. Suzuki, M. Tanihara, Y. Imanishi, and K. Awazu, "Free Electron Laser Induces Specific Immobilization of Heparin on Polysulfone Films," J. Biomat. Sci.-Polym. Ed., 12, 503 (2001).
36. Zhang, F., E. T. Kang, K. G. Neoh, and W. Huang, "Modification of Gold Surface by Grafting of Poly (ethylene glycol) for Reduction in Protein Adsorption and Platelet Adhesion," J. Biomat. Sci.-Polym. Ed., 12, 515 (2001).
37. Zhang, X., E. T. Kang, and K. G. Neoh, "Surface Studies of Pristine and Surface-Modified Polypyrrole Films," J. Appl. Polym. Sci., 60, 625 (1996).
38. Zhou, D., C. O. Too, and G. G. Wallace, "Synthesis and Characterization of Polypyrrole/Heparin Composites," React. Funct. Polym., 39, 19 (1999).