Interpretation of platelet inhibition by clopidogrel and the effect of non-responders

Journal of Thrombosis and Haemostasis

Volumn 1, Issue 6, 2003, Pages 1318-1319

  Gurbel, P A ^a   Bliden, K P ^a  

^a SINAI CENTER FOR THROMBOSIS RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBOCYTIC AGENT; CLOPIDOGREL; DRUG DERIVATIVE; TICLOPIDINE;

DRUG EFFECT; HUMAN; LETTER; STATISTICAL MODEL; THROMBOCYTE ACTIVATION; TREATMENT OUTCOME;

HUMANS; MODELS, STATISTICAL; PLATELET ACTIVATION; PLATELET AGGREGATION INHIBITORS; TICLOPIDINE; TREATMENT OUTCOME;

EID: 2142817072     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1046/j.1538-7836.2003.t01-3-00326.x     Document Type: Letter

References (3)

1. Savcic M, Hauert J, Bachmann F, Wyld PJ, Geudelin B, Cariou R. Clopidogrel loading dose regimens: kinetic profile of pharmacodynamic response in healthy subjects. Semin Thromb Hemost 1999; 25: 15-9.
2. Gurbel PA, Malinin AI, Callahan KP, Serebruany VL, O'Connor CM. Effect of loading with clopidogrel at the time of coronary stenting on platelet aggregation and GP Ilb/IIIa expression and platelet-leukocyte aggregate formation. Am J Cardiol 2002; 90: 312-5.
3. Gurbel PA, Serebruany VL, Shustov AR, Bahr RD, Carpo C, Ohman EM, Topol EJ for the GUSTO III investigators. Effects of reteplase and alteplase on platelet aggregation and major receptor expression during the first 24 hours of acute myocardial infarction treatment. J Am Coll Cardiol 1998; 31: 1466-73.