Effect of citrus aurantium extract on L-type calcium currents in ventricular myocytes of single guinea pigs

Bulletin of Hunan Medical University

Volumn 28, Issue 4, 2003, Pages 353-356

  Fang, Fang ^a   Dong, Min ^a   Zhu, Hong ^a  

^a Central South University   (China)

Author keywords

Chinese materia medica; Citrus aurantium extract; Guinea pigs; L type calcium current; Patch clamp; Ventricular myocyte

Indexed keywords

CALCIUM CHANNEL L TYPE; CALCIUM ION; CITRUS AURANTIUM EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG; VERAPAMIL; HERBACEOUS AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CHANNEL GATING; CITRUS FRUIT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION; ENZYME DISSOCIATION METHOD; GUINEA PIG; HEART MUSCLE CELL; HEART VENTRICLE; MEDICINAL PLANT; MUSCLE CELL; NONHUMAN; PATCH CLAMP; SOUR ORANGE; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; ANIMAL; CHEMISTRY; DRUG EFFECT; METABOLISM; PHYSIOLOGY;

ANIMALS; CALCIUM CHANNELS, L-TYPE; CITRUS; DRUGS, CHINESE HERBAL; GUINEA PIGS; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES;

EID: 2142802074     PISSN: 10005625     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Fang YX, Huang DS, Li C, et al. The beneficial effect of citrus aurantium extract injection (CAE) on acute drug-induced heart failure and cardiogenic shock in the dog [J]. Shock (submitted).
2. Liang Y, Wu BW, Dun W. Blocking effects of phentolamine on L-type calcium current and ATP-sensitive potassium current in guines pig ventricular myocytes [J]. Acta pharmacological sinica, 1998, 19(2):154-157.
3. Guo DL, Zhou ZN, Zeng FD, et al. Dauticine inhibited L-type calcium current in single cardiomyocyte of guinea pig [J]. Acta pharmacological sinica, 1997, 18(5):419-421.
4. Isenberg G, Klockner V. Calcium tolerant ventricular myocytes prepared by preincubation in a "KB medium" [J]. Pflugers Arch, 1982, 395:6-18.
5. Hamill O P, Marty A, Neher E, et al. Improved patch-Clamp techniques for High-resolution current recording from cells and cell free membrane patches [J]. Pflugers Arch, 1981, 391:85-100.