Correlation of pulmonary 99mtc‐dtpa ventilation and 99mtc‐maa perfusion scans with pulmonary function tests in asymptomatic asthmatic children

Nuclear Medicine Communications

Volumn 24, Issue 7, 2003, Pages 819-824

  Dai, Z K ^a   Chen, Y W ^a   Hsu, J H ^a   Huang, M S ^b   Chou, S H ^b   WU, J R ^b  

^a Nuclear Medicine   (United States)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Airway obstruction; Asthma,; Maximal midexpiratory flow rate; Perfusion; Pulmonary function test; Scintigraphy; Ventilation

Indexed keywords

DIAGNOSTIC AGENT; MACROSALB TC 99M; PENTETATE TECHNETIUM TC 99M; RADIOPHARMACEUTICAL AGENT;

ADOLESCENT; ARTICLE; ASTHMA; CHILD; CLINICAL TRIAL; COMPARATIVE STUDY; FORCED EXPIRATORY VOLUME; HUMAN; IN VITRO STUDY; INHALATIONAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; LUNG; LUNG FUNCTION TEST; LUNG VENTILATION PERFUSION RATIO; MALE; METHODOLOGY; REPRODUCIBILITY; SCINTISCANNING; SENSITIVITY AND SPECIFICITY; SPIROMETRY; VALIDATION STUDY; VASCULARIZATION;

ADMINISTRATION, INHALATION; ADOLESCENT; ASTHMA; CHILD; FORCED EXPIRATORY VOLUME; HUMANS; INJECTIONS, INTRAVENOUS; LUNG; MALE; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; RESPIRATORY FUNCTION TESTS; SENSITIVITY AND SPECIFICITY; SPIROMETRY; TECHNETIUM TC 99M AGGREGATED ALBUMIN; TECHNETIUM TC 99M PENTETATE; VENTILATION-PERFUSION RATIO;

EID: 2142799123     PISSN: 01433636     EISSN: 14735628     Source Type: Journal    
DOI: 10.1097/00006231-200307000-00012     Document Type: Article

References (27)

1. Fish JE, Peters SP. Airway remodeling and persistent airway obstruction in asthma. J Allergy Clin Immunol 1999; 104: 509-516.
2. Kavuru MS, Dweik RA, Thomassen MJ. Role of bronchoscopy in asthma research. Clin Chest Med 1999; 20: 153-189.
3. Williams SJ, Pierce RJ, Davies NJ, Denison DM. Methods of studying lobor and segmental function of the lung in man. Br J Dis Chest 1979; 73: 97-112.
4. Agnew JE, Bateman JR, Pavia D, Clarke SW. Radionuclide demonstration of ventilatory abnormalities in mild asthma. Clin Sci 1984; 66: 525-531.
5. Agnew JE, Wood EJ, Sutton PP, Bateman JR, Pavia D, Clarke SW. Krypton-81m and 5-micron radioaerosol images in asymptomatic asthma: a blind marking assessment. Eur J Nucl Med 1984; 9: 502-507.
6. Munkner T, Bundgaard A. Regional V/Q changes in asthmatics after exercise. Eur J Respir Dis 1986; 143: 62-66.
7. Kao CH, Liao SQ, Wang SJ, Yeh SH. Pulmonary scintigraphic findings in children with pectus excavatum by the comparison of chest radiograph indices. Clin Nucl Med 1992; 17: 874-876.
8. Rao M, Steiner P, Victoria MS, et al. Regional lung functions in children with asthma. J Asthma Res 1977; 14: 107-110.
9. Global Initiative for Asthma. Global strategy for asthma management and prevention. NHLBI/WHO Workshop Report. Chapter 5: Diagnosis and Classification. National Institutes of Health. National Heart, Lung, and Blood Institute. Publication Number 2002. Bethesda: National Institutes of Health, 2000: 74-75.
10. Vernon P, Burton HG, Seed WA. Lung scan abnormalities in asthma and their correlation with lung function. Eur J Nucl Med 1986; 12: 16-20.
11. Hayes M, Taplin GV. Lung imaging with radioaerosols for the assessment of airway disease. Semin Nucl Med 1980; 10: 243-251.
12. Altes TA, Powers PL, Knight-Scott J, et al. Hyperpolarized 3He MR lung ventilation imaging in asthmatics: preliminary findings. J Magn Reson Imaging 2001; 13: 378-384.
13. Kohn H, Mostbeck A, Bachmayr S, et al. 99mTc-DTPA aerosol for same-day post-perfusion ventilation imaging: results of a multicentre study. Eur J Nucl Med 1993; 20: 4-9.
14. Hoshi H, Dadparvar S, Promisloff R, et al. Mismatch between 99mTc-DTPA aerosol and 81mKr lung ventilation scintigraphy: a pitfall of radionuclide imaging. Eur Nucl Med 1990; 16: 121-123.
15. Santolicandro A, Ruschi S, Fornai E, Giuntini C. Imaging of ventilation in chronic obstructive pulmonary disease. J Thorac Imaging 1986; 1: 36-53.
16. Taplin GV, Chopra SK. Lung perfusion-inhalation scintigraphy in obstructive airway disease and pulmonary embolism. Radiol Clin North Am 1978; 16: 491-513.
17. Bentivoglio LG, Beerel F, Bryan AC, Stewart PB, Rose B, Bates DV. Regional pulmonary function studied with xenon in patients with bronchial asthma. J Clin Invest 1963; 42: 1193-1200.
18. Papanicolaou N, Treves S. Pulmonary scintigraphy in pediatrics. Semin Nucl Med 1980; 10: 259-285.
19. Lopez-Majano V, Wagner Jr HN, Twining RH, Tow DE, Chernick V. Effect of regional hypoxia on the distribution of pulmonary blood flow in man. Circ Res 1966; 18: 550-557.
20. Marshall C, Marshall BE. Hypoxic pulmonary vasoconstriction is not endothelium dependent. Proc Soc Exp Biol Med 1992; 201: 267-270.
21. Robinson AE, Goodrich JK, Spock A. Inhalation and perfusion radionuclide studies of pediatric chest disease. Radiology 1969; 93: 1123-1128.
22. Wilson AF, Suprenant EL, Beall GN, Siegel SC, Simmons DH, Bennett LR. The significance of regional pulmonary function changes in bronchial asthma. Am J Med 1970; 48: 416-423.
23. Wagner EM, Foster WM. The role of the bronchial vasculature in soluble particle clearance. Environ Health Perspect 2001; 109(suppl 4): 563-565.
24. Freyschuss U, Hedlin G, Hedenstierna G. Ventilation-perfusion relationships during exercise-induced asthma in children. Am Rev Respir Dis 1984; 130: 888-894.
25. Burton GH, Seed WA, Vernon P. Computer analysis of ventilation-perfusion scans for detection and assessment of lung disease. Thorax 1985; 40: 519-525.
26. Wanger J. Spirometry. In: Wanger J, ed. Pulmonary function testing: a practical approach. Baltimore: Williams & Wilkins, 1992: 1-62.
27. Bjermer L. Histories and future perspectives of treating asthma as a systemic and small airways disease. Resp Med 2001; 95: 703-719.