Preparation and rectal absorption of highly concentrated glycyrrhizin solution

Biological and Pharmaceutical Bulletin

Volumn 26, Issue 9, 2003, Pages 1299-1305

  Koga, Kenjiro ^a   Kawashima, Susumu ^a   Shibata, Nobuhito ^b   Takada, Kanji ^b   Murakami, Masahiro ^b,c  

^a HOKURIKU UNIVERSITY   (Japan)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^c Laboratories of Excellent Medicine   (Japan)

Author keywords

Gel formation; Glycyrrhizin; Phosphate buffered solution; Rat; Rectal absorption

Indexed keywords

GLYCEROL; GLYCYRRHIZIC ACID DERIVATIVE; MACROGOL; PROPYLENE GLYCOL; ANTIVIRUS AGENT; BUFFER; GLYCYRRHIZIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS SOLUTION; AREA UNDER THE CURVE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG ABSORPTION; DRUG FORMULATION; DRUG SYNTHESIS; HISTOLOGY; IN VITRO STUDY; MALE; NONHUMAN; PERMEABILITY; PH MEASUREMENT; RAT; RECTUM MUCOSA; SOLVENT EFFECT; STATISTICAL SIGNIFICANCE; VISCOMETRY; ALGORITHM; ANIMAL; BIOAVAILABILITY; CHEMISTRY; GEL; INTESTINE ABSORPTION; LARGE INTESTINE; METABOLISM; PHYSICAL CHEMISTRY; RECTAL DRUG ADMINISTRATION; RECTUM; SOLUBILITY; SOLUTION AND SOLUBILITY; TEMPERATURE; THERMODYNAMICS; WISTAR RAT;

ADMINISTRATION, RECTAL; ALGORITHMS; ANIMALS; ANTIVIRAL AGENTS; BIOLOGICAL AVAILABILITY; BUFFERS; CHEMISTRY, PHARMACEUTICAL; CHEMISTRY, PHYSICAL; GELS; GLYCYRRHIZIC ACID; INTESTINAL ABSORPTION; INTESTINE, LARGE; MALE; PHARMACEUTICAL SOLUTIONS; RATS; RATS, WISTAR; RECTUM; SOLUBILITY; TEMPERATURE; THERMODYNAMICS;

EID: 2142771660     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.26.1299     Document Type: Article

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