The production of homogeneous extrudates of microcrystalline cellulose pastes

International Journal of Pharmaceutics

Volumn 276, Issue 1-2, 2004, Pages 185-189

  Rough, S L ^a   Wilson, D I ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Liquid migration; Microcrystalline cellulose; Paste extrusion

Indexed keywords

MICROCRYSTALLINE CELLULOSE;

ARTICLE; DRUG DOSAGE FORM; DRUG FORMULATION; LIQUID PHASE MICROEXTRACTION; PASTE; PRIORITY JOURNAL; WATER CONTENT; WATER LOSS;

CELLULOSE; CHEMISTRY, PHARMACEUTICAL; OINTMENTS;

EID: 2142751546     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2004.02.021     Document Type: Article

References (4)

1. Bains D., Boutell S.L., Newton J.M. The influence of moisture content on the preparation of spherical granules of barium sulphate and microcrystalline cellulose. Int. J. Pharm. 69:1991;233-237
2. Burbidge A.S., Bridgwater J., Saracevic Z. Liquid migration in paste extrusion. Trans. IChemE. 73:1995;810-816
3. Rough S.L., Bridgwater J., Wilson D.I. Effects of phase migration on extrusion of microcrystalline cellulose pastes. Int. J. Pharm. 204:2000;117-126
4. Vervaet C., Baert L., Remon J.P. A literature review - extrusion-spheronisation. Int. J. Pharm. 116:1995;131-146