Vasorelaxation and hyperpolarisation of rat small mesenteric artery by the quaternary anion tetraphenylboron

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 369, Issue 4, 2004, Pages 367-373

  Favaloro, Joanne L ^a   McPherson, Grant A ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Hyperpolarisation; KATP channels; Quaternary ions; Tetraphenylboron; Vasorelaxation

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 4 AMINOPYRIDINE DERIVATIVE; APAMIN; BARIUM ION; CHARYBDOTOXIN; GLIBENCLAMIDE; METHOXAMINE; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM ION; TETRAPHENYLBORON; VASOPRESSIN;

ANIMAL TISSUE; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; HYPERPOLARIZATION; MALE; MESENTERIC ARTERY; MYOGRAPHY; NONHUMAN; RAT; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE FIBER; SMOOTH MUSCLE FIBER MEMBRANE POTENTIAL; VASODILATATION;

ANIMALS; CELL MEMBRANE; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MEMBRANE POTENTIALS; MESENTERIC ARTERY, INFERIOR; MUSCLE, SMOOTH, VASCULAR; POTASSIUM; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; RATS; RATS, SPRAGUE-DAWLEY; TETRAPHENYLBORATE; VASODILATION; VASODILATOR AGENTS;

EID: 2142657855     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-004-0879-8     Document Type: Article

References (21)

1. Challinor J, McPherson G (1993) Evidence that imidazol(id)ine-and sulphonylurea-based antagonists of cromakalim act at different sites in the rat thoracic aorta. Clin Exp Pharmacol Physiol 20:467-475
2. Guideri G, Seifter E, Seifter J (1974) Effects of tetraphenylboron (TPB) on the autonomic nervous system. Arch Int Pharmacodyn Ther 208:224-234
3. Haydon DA, Hladky SB (1972) Ion transport across thin lipid membranes: a critical discussion of mechanisms in selected systems. Q Rev Biophys 5:187-282
4. Heginbotham L, McKinnon R (1992) The aromatic binding site for tetraethylammonium ion on potassium channels. Neuron 8:483-491
5. Holevinsky KO, Fan Z, Frame M, Makielski JC, Groppi V, Nelson DJ (1994) ATP-sensitive K+ channel opener acts as a potent inhibitor in vascular smooth muscle cells. J Membr Biol 137: 59-70
6. Kenakin TP (1987) Pharmacologic analysis of drug-receptor interaction. Raven, New York
7. Klodos I, Fedosova NU, Plesner L (1995) Influence of intramembrane electric charge on Na/K-ATPase. J Biol Chem 270:4244-4254
8. Liberman EA, Topaly VP (1968) Selective transport of ions through biomolecular phospholipid membranes. Biochim Biophys Acta 163:125-136
9. Liu GH, Oba T (1990) Effects of tetraphenylboron-induced increase in inner surface charge on Ca2+ release from sarcoplasic reticulum. Jpn J Physiol 40:723-736
10. McPherson G (1992) Optimal conditions assessing vascular reactivity in small resistance arteries in the small vessel myograph. Clin Exp Pharmacol Physiol 19:815-825
11. McPherson G, Angus J (1991) Evidence that acetylcholine-mediated hyperpolarization of the rat small mesenteric artery does not involve the K+ channel opened by cromakalim. Br J Pharmacol 103:1184-1190
12. McPherson GA, Piekarska AE (1994) Antagonism by lipophilic quarternary ions of the K+ channel opener, levcromakalim, in vascular smooth muscle. Br J Pharmacol 112:1223-1229
13. Mulvany MJ, Halpern W (1977) Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rat. Circ Res 41:19-26
14. Murphy M, Krueger M, Sablin S, Ramsay R, Singer T (1995) Inhibition of complex I by hydrophobic analogues of N-methyl-4-phenylpyridinium (MPP+) and the use of an ion-selective electrode to measure the accumulation by mitochondria and electron-transport patches. Biochem J 306:359-365
15. Nelson M, Quayle J (1995) Physiological roles and properties of potassium channels in arterial smooth muscle. Am J Physiol 268:C799-C822
16. Piekarska AE, McPherson GA (1997) Structure-activity relationship of quarternary ion antagonism of levcromakalin-induced relaxation of the pig coronary artery. Eur J Pharmacol 322:37-44
17. Saito S, Murakami Y, Miyauchi S, Kamo N (1992) Measurement of plasma membrane potential in isolated rat hepatocytes using the lipophilic cation, tetraphenylphosphonium: correction of probe intracellular binding and mitochondrial accumulation. Biochem Biophys Acta 1111:221-230
18. Sedgwick EG, Bragg PD (1993) Mechanism of uptake of the fluorescent dye 2-(4-dimethylaminostyryl)-1-ethylpyridinium cation (DMP+) by phospholipid vesicles. Biochem Biophys Acta 1146: 113-120
19. Seifter J, Guideri G, Seifter E (1968) Effect of tetraphenylboron (Ph4B), a negative quaternary, on muscle contraction and enzyme action: a new view of activation and blockade of cholinergic receptors. Eur J Pharmacol 3:262
20. Utsumi K, Packer L (1967) Uncoupling of energy transfer reactions in mitochondria by tetraphenyl Boron. Arch Biochem Biophys 122:509-515
21. Zhang H, Bolton TB, Piekarska AE, McPherson GA (1998) The electrophysiological effects of tetraphenylphosphonium on vascular smooth muscle. Eur J Pharmacol 347:119-123