Synthesis, antiviral and cytotoxic activity of 6-bromo-2,3-disubstituted- 4(3H)-quinazolinones

Biological and Pharmaceutical Bulletin

Volumn 26, Issue 9, 2003, Pages 1278-1282

  Dinakaran, Murugesan ^a   Selvam, Periyaswamy ^a   DeClercq, Erik ^b   Sridhar, Seshaiah Krishnan ^c  

^a Periyar College of Pharmaceutical Sciences for Girls   (India)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^c C L BAID METHA COLLEGE OF PHARMACY   (India)

Author keywords

Anti HIV; Antiviral; Cytotoxicity; Quinazoline

Indexed keywords

6 BROMO 2 METHYL 3 [4 AMINO 5 (3,4,5 TRIMETHOXYBENZYL)PYRIMIDIN 2 YL] 4(3H) QUINAZOLINONE; 6 BROMO 2 METHYL 3 [4 AMINO 5 (4 CHLOROPHENYL) 6 ETHYLPYRIMIDIN 2 YL] 4(3H) QUINAZOLINONE; 6 BROMO 2 METHYL 3 [5 AMINO 6 (2,3 DICHLOROPHENYL) 1,2,4 TRIAZIN 3 YL] 4(3H) QUINAZOLINONE; 6 BROMO 2 PHENYL 3 [4 AMINO 5 (3,4,5 TRIMETHOXYBENZYL)PYRIMIDIN 2 YL] 4(3H) QUINAZOLINONE; 6 BROMO 2 PHENYL 3 [4 AMINO 5 (4 CHLOROPHENYL) 6 ETHYLPYRIMIDIN 2 YL] 4(3H) QUINAZOLINONE; 6 BROMO 2 PHENYL 3 [5 AMINO 6 (2,3 DICHLOROPHENYL) 1,2,4 TRIAZIN 3 YL] 4(3H) QUINAZOLINONE; ANTIVIRUS AGENT; BENZOXAZINONE DERIVATIVE; CYTOTOXIC AGENT; LAMOTRIGINE; PYRIMETHAMINE; QUINAZOLINONE DERIVATIVE; TRIMETHOPRIM; UNCLASSIFIED DRUG; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTINEOPLASTIC AGENT; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; QUINAZOLINE DERIVATIVE;

ANALYTIC METHOD; ANTIVIRAL ACTIVITY; ARTICLE; CELL PROTECTION; CELL VIABILITY; CHEMICAL STRUCTURE; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; COXSACKIE VIRUS B4; CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ELEMENTAL ANALYSIS; HELA CELL; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN IMMUNODEFICIENCY VIRUS 1; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; NONHUMAN; PARAINFLUENZA VIRUS 3; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; PUNTA TORO VIRUS; REOVIRUS; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; SINDBIS VIRUS; STRUCTURE ANALYSIS; SUBSTITUTION REACTION; VACCINIA VIRUS; VESICULAR STOMATITIS VIRUS; VIRUS; VIRUS CULTURE; VIRUS INHIBITION; VIRUS REPLICATION; VIRUS STRAIN; CELL LINE; DRUG EFFECT; DRUG SCREENING; ELECTROSPRAY MASS SPECTROMETRY; INFRARED SPECTROPHOTOMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS; TUMOR CELL LINE;

ANTI-HIV AGENTS; ANTINEOPLASTIC AGENTS; ANTIVIRAL AGENTS; CELL LINE; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; PLAQUE ASSAY; QUINAZOLINES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, INFRARED; VIRUSES;

EID: 2142656299     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.26.1278     Document Type: Article

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