In Vitro Activity of a Novel Diaminopyrimidine Compound, Iclaprim, against Chlamydia trachomatis and C. pneumoniae

Antimicrobial Agents and Chemotherapy

Volumn 48, Issue 5, 2004, Pages 1885-1886

  Kohlhoff, S A ^a,c   Roblin, P M ^a   Reznik, T ^a   Hawser, S ^b   Islam, K ^b   Hammerschlag, M R ^a  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

^b Arpida Ltd   (Switzerland)

^c SUNY Downstate Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; DIAMINOPYRIMIDINE DERIVATIVE; DIHYDROFOLATE REDUCTASE INHIBITOR; ICLAPRIM; LEVOFLOXACIN; TRIMETHOPRIM; UNCLASSIFIED DRUG;

ARTICLE; BACTERICIDAL ACTIVITY; BACTERIUM ISOLATE; CHLAMYDIA TRACHOMATIS; CHLAMYDOPHILA PNEUMONIAE; CONTROLLED STUDY; GENITAL TRACT INFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MINIMUM BACTERICIDAL CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION;

ANTI-BACTERIAL AGENTS; AZITHROMYCIN; CHLAMYDIA INFECTIONS; CHLAMYDIA TRACHOMATIS; CHLAMYDOPHILA PNEUMONIAE; FOLIC ACID ANTAGONISTS; HUMANS; MICROBIAL SENSITIVITY TESTS; OFLOXACIN; PYRIMIDINES;

EID: 2142646449     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.48.5.1885-1886.2004     Document Type: Article

References (3)

1. Fan, H., R. C. Brunham, and G. McClarty. 1992. Acquisition and synthesis of folates by obligate intracellular bacteria of the genus Chlamydia. J. Clin. Investig. 90:1803-1811.
2. Hammerschlag, M. R. 1982. Activity of trimethoprim-sulfamethoxazole against Chlamydia trachomatis in vitro. Rev. Infect. Dis. 4:500-504.
3. Roblin, P. M., T. Reznik, and M. R. Hammerschlag. 2002. In vitro activity of garenoxacin against recent clinical isolates of Chlamydia pneumoniae. Int. J. Antimicrob. Agents 21:578-580.