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Volumn 46, Issue 31, 2005, Pages 5113-5115

An expeditious hydroxyamidation of carboxylic acids

Author keywords

Fatty acids, PPAA; Hydroxamic acids; Hydroxyamidation; Oleic acid

Indexed keywords

ACID ANHYDRIDE; CARBOXYLIC ACID; HYDROXAMIC ACID; HYDROXYACID; HYDROXYLAMINE;

EID: 21344469061     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.05.131     Document Type: Article
Times cited : (33)

References (18)
  • 5
    • 21344443692 scopus 로고    scopus 로고
    • note
    • 1H NMR analysis) of mono- and diacyl derivatives was obtained.
  • 15
    • 21344432581 scopus 로고    scopus 로고
    • note
    • Reverse addition of a carboxylic acid to a mixture of PPAA, hydroxylamine, and TEA, gave a lower hydroxamate yield (16% with oleic acid) compared to the direct addition, suggesting a certain competition between carboxylate and hydroxylamine for phosphonylation.
  • 16
    • 21344462376 scopus 로고    scopus 로고
    • note
    • 13C NMR, IR and ESI-MS.
  • 17
    • 21344447764 scopus 로고    scopus 로고
    • note
    • However, attempts to oxyamidate betulinic acid, an even more encumbered triterpenoid substrate, failed.
  • 18
    • 21344457006 scopus 로고    scopus 로고
    • note
    • Since p-methoxy- and p-nitrobenzoic acids gave yields similar to that of benzoic acid, the origin of this effect is unclear.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.