Oxidative stress in portal hypertension-induced rats with particular emphasis on nitric oxide and trace metals

World Journal of Gastroenterology

Volumn 11, Issue 23, 2005, Pages 3570-3573

  Izzet, Titiz ^a   Osman, Krand ^a   Ethem, Unal ^a,c   Nihat, Yavuz ^b   Ramazan, Kusaslan ^b   Mustafa, Dogan ^b   Hafize, Uzun ^b   Ali Riza, Kiziler ^b   Birsen, Aydemir ^b   Habibe, Genc ^b   Seval, Aydin ^b   Gonul, Simsek ^b  

^a GATA HAYDARPASA TRAINING HOSPITAL   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

^c NONE   (Turkey)

Author keywords

Antioxidants; Lipid peroxidation; Nitric oxide; Portal hypertension; Trace metals

Indexed keywords

CATALASE; COPPER; GLUTATHIONE; HYDROGEN PEROXIDE; MALONALDEHYDE; NITRATE REDUCTASE; NITRIC OXIDE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID; XANTHINE; XANTHINE OXIDASE; ZINC;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; CONTROLLED STUDY; COPPER BLOOD LEVEL; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER CIRRHOSIS; MALE; NITROBLUE TETRAZOLIUM TEST; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PORTAL HYPERTENSION; PORTAL VEIN BLOOD PRESSURE; PRECIPITATION; RANK SUM TEST; RAT; RAT STRAIN; STATISTICAL SIGNIFICANCE; STUDENT T TEST; TISSUE LEVEL; VEIN LIGATION; ZINC BLOOD LEVEL;

EID: 21344467235     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i23.3570     Document Type: Article

References (29)

1. Huang YT, Hsu YC, Chen CJ, Liu CT, Wei YH. Oxidative-stress-related changes in the livers of bile-duct-ligated rats. J Biomed Sci 2003; 10: 170-178
2. Bomzon A, Ljubuncic P. Oxidative stress and vascular smooth muscle cell function in liver disease. Pharmacol Ther 2001; 89: 295-308
3. Wang H, Chen XP, Qiu FZ. Salviae miltiorrhizae ameliorates cirrhosis and portal hypertension by inhibiting nitric oxide in cirrhotic rats. Hepatobiliary Pancreat Dis Int 2003; 2: 391-396
4. Chetri K, Choudhuri G. Role of trace elements in hepatic encephalopathy: zinc and manganese. Indian J Gastroenterol 2003; 22(Suppl 2): S28-30
5. Hiiemae K, Rozmiarek H, Williams JF, LeBeau JE, Ross M. Report of a panel discussion on how to run an effective Animal Care and Use Committee. Lab Anim Sci 1987; 37: 39-44
6. Hsieh JS, Huang TJ. The effect of portal hypertension on gastric epithelial proliferation in rats. Eur Surg Res 1993; 25: 98-103
7. Angel MF, Ramasastry SS, Swartz WM, Narayanan K, Kuhns DB, Basford RE, Futrell JW. The critical relationship between free radicals and degrees of ischemia: Evidence for tissue intolerance of marginal perfusion. Plastic Reconstructive Surg 1988; 81: 233-259
8. Lowry OH, Rosenbrough NJ, Farr AC, Randall RJ. Protein measurement with the folin phenol regent. J Biol Chem 1951; 913: 265-275
9. Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR. Analysis of nitrate, nitrite and [15N] nitrate in biological fluids. Anal Biochem 1982; 126: 131-138
10. Sun Y, Oberly LW, Ying LA. Simple method for clinical assay of superoxide dismutase. Clin Chem 1988; 34: 497-500
11. Yasmineh WG, Kaur TP, Blazar BR, Theologides A. Serum catalase as marker of Graft-Versus-Host Disease in allogenic bone marrow transplant recipients: pilot study. Clin Chem 1995; 41: 1574-1580
12. Beutler E, Duran O, Kelly BM. Improved method for the determination of blood glutathione. J Lab Clin Med 1963; 51: 882-888
13. Evelson P, Llesuy S, Filinger E, Rodriguez RR, Lemberg A, Scorticati C, Susemihl M, Villareal I, Polo JM, Peredo H, Perazzo JC. Decreased oxidative stress in prehepatic portal hypertensive rat livers following the induction of diabetes. Clin Exp Pharmacol Physiol 2004; 31: 169-173
14. Huang HC, Wang SS, Chan CC, Lee FY, Chang FY, Lin HC, Hou MC, Tai CC, Lai IN, Lee SD. Chronic inhibition of nitric oxide increases the collateral vascular responsiveness to vasopressin in portal hypertensive rats. J Hepatol 2004; 40: 234-238
15. Ozturk H, Yagmur Y, Buyukbayram H, Dokucu AL, Gurel A. Effects of the nitric oxide donor molsidomine on the early stages of liver damage in rats with bile duct ligation: a biochemical and immunohistochemical approach. Eur Surg Res 2002; 34: 285-290
16. Gonzalez-Abraldes J, Garcia-Pagan JC, Bosch J. Nitric oxide and portal hypertension. Metab Brain Dis 2002; 17: 311-324
17. Bhimani EK, Serracino-Inglott F, Sarela AI, Batten JJ, Mathie RT. Hepatic and mesenteric nitric oxide synthase expression in a rat model of CCl(4)-induced cirrhosis. J Surg Res 2003; 113: 172-178
18. Goksu N, Ozsoylu S. Hepatic and serum levels of zinc, copper, and magnesium in childhood cirrhosis. J Pediatr Gastroenterol Nutr 1986; 5: 459-462
19. Scholmerich J, Becher MS, Kottgen E, Rauch N, Haussinger D, Lohle E, Vuilleumier JP, Gerok W. The influence of portosystemic shunting on zinc and vitamin A metabolism in liver cirrhosis. Hepatogastroenterology 1983; 30: 143-147
20. Kaur S, Kaur U, Tandon C, Dhawan V, Ganguly NK, Majumdar S. Gastropathy and defense mechanisms in common bile duct ligated portal hypertensive rats. Mol Cell Biochem 2000; 203: 79-85
21. Naito Y, Yoshikawa T, Boku Y, Fujii T, Masui Y, Tanaka Y, Fujita N, Yoshida N, Kondo M. Protective role of intracellular glutathione against nitric oxide-induced necrosis in rat gastric mucosal cells. Aliment Pharmacol Ther 2000; 14(Suppl 1): 145-152
22. Loguercio C, Taranto D, Vitale LM, Beneduce F, Del Vecchio Blanco C. Effect of liver cirrhosis and age on the glutathione concentration in the plasma, erythrocytes, and gastric mucosa of man. Free Radic Biol Med 1996; 20: 483-488
23. Shams V, Erkan T, Gumustas MK, Cullu F, Kutlu T, Kaya H, Aydin S, Tumay G. The role of nitric oxide in pediatric patients with portal hypertension. J Trop Pediatr 2003; 49: 33-36
24. Farzaneh-Far R, Moore K. Nitric oxide and the liver. Liver 2001; 21: 161-174
25. Yang W, Benjamin IS, Moore K, Portmann B, Alexander B. The action of nitric oxide on hepatic haemodynamics during secondary biliary cirrhosis in the rat. Eur J Pharmacol 2003; 461: 41-48
26. Kiefer FN, Neysari S, Humar R, Li W, Munk VC, Battegay EJ. Hypertension and angiogenesis. Curr Pharm Des 2003; 9: 1733-1744
27. Arkenau HT, Stichtenoth DO, Frolich JC, Manns MP, Boker KH. Elevated nitric oxide levels in patients with chronic liver disease and cirrhosis correlate with disease stage and parameters of hyperdynamic circulation. Gastroenterology 2002; 40: 907-913
28. Ebara M, Fukuda H, Hatano R, Yoshikawa M, Sugiura N, Saisho H, Kondo F, Yukawa M. Metal contents in the liver of patients with chronic liver disease caused by hepatitis C virus. Reference to hepatocellular carcinoma. Oncology 2003; 65: 323-330
29. Stehbens WE. Oxidative stress, toxic hepatitis, and antioxidants with particular emphasis on zinc. Exp Mol Pathol 2003; 75: 265-276