Healing of dehiscence defects following root surface demineralization with tetracycline: A histologic study in monkeys

Journal of Periodontology

Volumn 76, Issue 6, 2005, Pages 908-914

  Nagata, Maria J H ^a,b   Bosco, Alvaro F ^a   Leite, Cristiane M ^a   Melo, Luiz G N ^a   Sundefeld, Maria L M M ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b NONE   (Brazil)

Author keywords

Animal studies; Bone, demineralized; Periodontal attachment; Periodontal regeneration; Tetracycline therapeutic use; Tooth anatomy and histology

Indexed keywords

SODIUM CHLORIDE; TETRACYCLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE REGENERATION; CEMENTUM; COMPUTER AIDED DESIGN; CONNECTIVE TISSUE; CONTROLLED STUDY; EPITHELIUM; EXPERIMENTAL DESIGN; HISTOPATHOLOGY; INCISOR; LAVAGE; MALE; MONKEY; MORPHOMETRICS; NONHUMAN; POSTOPERATIVE PERIOD; REPARATIVE DENTISTRY; STATISTICAL SIGNIFICANCE; SUTURING METHOD; TISSUE REGENERATION; TOOTH DISEASE; TOOTH ROOT; WOUND DEHISCENCE; WOUND HEALING;

ANIMALS; ANTI-BACTERIAL AGENTS; CEBUS; MALE; MODELS, ANIMAL; PERIODONTAL ATTACHMENT LOSS; SURFACE PROPERTIES; SURGICAL WOUND DEHISCENCE; TETRACYCLINE; TOOTH DEMINERALIZATION; TOOTH ROOT; WOUND HEALING;

EID: 21344466080     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2005.76.6.908     Document Type: Article

References (51)

1. Marshall JS. A remarkable case of pyorrhea alveolaris with reproduction of bone, occurring in the practice of Dr. Allport. JAMA 1883;1:641-646.
2. Younger WJ. Some of the latest phases in implantation and other operations. Dent Cosmos 1893;35:102-108.
3. Stewart HT. Partial removal of cementum and decalcification of tooth in the treatment of pyorrhea alveolaris. Dent Cosmos 1895;41:617-626.
4. Register AA, Burdick FA. Accelerated reattachment with cementogenesis to dentin, demineralized in situ. I. Optimum range. J Periodontol 1975;46:646-655.
5. Register AA, Burdick FA. Accelerated reattachment with cementogenesis to dentin, demineralized in situ II. Defect repair. J Periodontol 1976;47:497-505.
6. Caffesse RG, De La Rosa M, Garza M, Munne-Travers A, Mondragon JC, Weltman R. Citric acid demineralization and subepithelial connective tissue grafts. J Periodontol 2000;71:568-572.
7. Leidal TL, Eriksen HM. A scanning electron microscopic study of the effect of various cleansing agents on cavity walls in vitro. Scand J Dent Res 1979;87:443-449.
8. Zaman KU, Sugaya T, Hongo O, Kato H. A study of attached and oriented human periodontal ligament cells to periodontally diseased cementum and dentin after demineralizing with neutral and low pH etching solution. J Periodontol 2000;71:1094-1099.
9. Babay N. Attachment of human gingival fibroblasts to periodontally involved root surface following scaling and/or etching procedures: A scanning electron microscopy study. Braz Dent J 2001;12:17-21.
10. Wikesjö UME, Baker PJ, Christersson LA, et al. A biochemical approach to periodontal regeneration: Tetracycline treatment conditions dentin surfaces. J Periodontal Res 1986;21:322-329.
11. Trombelli L, Schincaglia GP, Zangari F, Griselli A, Scabbia A, Calura G. Effects of tetracycline HCl conditioning and fibrin-fibronectin system application in the treatment of buccal gingival recession with guided tissue regeneration. J Periodontol 1995;66:313-320.
12. Isik AG, Tarim B, Afees AA, Yalçin FS, Onan U, Cox CF. A comparative scanning electron microscopic study on the characteristics of demineralized dentin root surface using different tetracycline HCl concentrations and application times. J Periodontol 2000;71:219-225.
13. Trombelli L, Scabbia A, Zangari F, Griselli A, Wikesjö UME, Calura G. Effect of tetracycline HCl on periodontally-affected human root surfaces. J Periodontol 1995; 66:685-691.
14. Trombelli L, Scabbia A, Calura G. Nondiseased cementum and dentin root surface following tetracycline hydrochloride conditioning: SEM study of the effects of solution concentration and application time. Int J Periodontics Restorative Dent 1994;14:461-470.
15. Golub LM, Ramamurthy N, McNamara TF, et al. Tetracyclines inhibit tissue collagenase activity. A new mechanism in the treatment of periodontal disease. J Periodontal Res 1984;19:651-655.
16. Golub LM, Greenwald RA, Ramamurthy NS, McNamara TF, Rifkin BR. Tetracyclines inhibit connective tissue breakdown: New therapeutic implications for an old family of drugs. Crit Rev Oral Biol Med 1991;2:297-322.
17. Gomes BC, Golub LM, Ramamurthy NS. Tetracyclines inhibit parathyroid hormone-induced bone resorption in organ culture. Experientia 1984;40:1273-1275.
18. Rifkin BR, Vernillo AT, Golub LM. Blocking periodontal disease progression by inhibiting tissue-destructive enzymes: A potential therapeutic role for tetracyclines and their chemically-modified analogs. J Periodontol 1993;64:819-827.
19. Baker PJ, Evans RT, Coburn RA, Genco RJ. Tetracycline and its derivatives strongly bind to and are released from the tooth surface in active form. J Periodontol 1983;54:580-585.
20. Bjorvatn K. Scanning electron-microscopic study of pellicle and plaque formation on tetracycline-impregnated dentin. Scand J Dent Res 1986;94:89-94.
21. Glaber WL, Creamer HR. Suppression of human neutrophil functions by tetracyclines. J Periodontal Res 1991;26:52-58.
22. Terranova VP, Franzetti LC, Hic S, et al. A biochemical approach to periodontal regeneration: Tetracycline treatment of dentin promotes fibroblast adhesion and growth. J Periodontal Res 1986;21:330-337.
23. Trombelli L, Schincaglia G, Checchi L, Calura G. Combined guided tissue regeneration, root conditioning, and fibrin-fibronectin system application in the treatment of gingival recession. A 15-case report. J Periodontol 1994; 65:796-803.
24. Bouchard P, Nilveus R, Etienne D. Clinical evaluation of tetracycline HCl conditioning in the treatment of gingival recessions. A comparative study. J Periodontol 1997; 68:262-269.
25. Wang H, Hamilton RL, Castelli WA, Chiego DJ, Smith BA. Effect of root conditioning on periodontal wound healing with and without guided tissue regeneration: A pilot study. I. Histologic evaluation. Int J Periodontics Restorative Dent 1993;13:51-56.
26. Parashis AO, Mitsis FJ. Clinical evaluation of the effect of tetracycline root preparation on guided tissue regeneration in the treatment of Class II furcation defects. J Periodontol 1993;64:133-136.
27. Machtei EE, Dunford RG, Norderyd OM, Zambon JJ, Genco RJ. Guided tissue regeneration and anti-infective therapy in the treatment of Class II furcation defects. J Periodontol 1993;64:968-973.
28. Sammons PR, Wang H, Chiego DJ Jr, Castelli WA, Smith BA. Effect of root conditioning on periodontal wound healing with and without guided tissue regeneration: A pilot study. II. Autoradiographic evaluation. Int J Periodontics Restorative Dent 1994;14:63-69.
29. Polson AM, Proye MP. Fibrin linkage: A precursor for new attachment. J Periodontol 1983;54:141-147.
30. Wikesjö UME, Claffey N, Egelberg J. Periodontal repair in dogs: Effect of heparin treatment of the root surface. J Clin Periodontol 1991;18:60-64.
31. Wikesjö UME, Crigger M, Nilvéus RE, Selvig KA. Early healing events at the dentin-connective tissue interface. Light and transmission electron microscopy observations. J Periodontol 1991;62:5-14.
32. Wikesjö UME, Nilvéus RE, Selvig KA. Significance of early healing events on periodontal repair: A review. J Periodontol 1992;63:158-165.
33. Madison JG, Hokett SD. The effects of different tetracyclines on the dentin root surface of instrumented, periodontally involved human teeth: A comparative scanning electron microscope study. J Periodontol 1997;68:739-745.
34. Baker PJ, Rotch HA, Trombelli L, Wikesjö UME. An in vitro screening model to evaluate root conditioning protocols for periodontal regenerative procedures. J Periodontol 2000;71:1139-1143.
35. Rompen EH, Kohl J, Nusgens B, Lapière CM. Kinetic aspects of gingival and periodontal ligament fibroblast attachment to surface-conditioned dentin. J Dent Res 1993;72:607-612.
36. Alger FA, Salt CW, Vuddhakanok S, Miles K. The histologic evaluation of new attachment in periodontally-diseased human roots treated with tetracycline-hydrochloride and fibronectin. J Periodontol 1990;61:447-455.
37. Wikesjö UME, Selvig KA. Periodontal wound healing and regeneration. Periodontol 2000 1999;19:21-39.
38. Haney JM, Zimmerman GJ, Wikesjö UME. Periodontal repair in dogs: Evaluation of the natural disease model. J Clin Periodontol 1995;22:208-213.
39. Wikesjö UME, Selvig KA, Zimmerman G, Nilvéus RE. Periodontal repair in dogs: Healing in experimentally created chronic periodontal defects. J Periodontol 1991; 62:258-263.
40. Jones WA, O'Leary TJ. The effectiveness of in vitro root planing in removing bacterial endotoxin from the roots of periodontally involved teeth. J Periodontol 1978;49: 337-342.
41. Frantz B, Polson A. Tissue interactions with dentin specimens after demineralization using tetracycline. J Periodontol 1988;59:714-721.
42. Hanes PJ, O'Brien NJ, Garnick JJ. A morphological comparison of radicular dentin following root planing and treatment with citric acid and tetracycline HCl. J Clin Periodontol 1991;18:660-668.
43. Claffey N, Bogle G, Björvatn K, Selvig KA, Egelberg J. Topical application of tetracycline in regenerative periodontal surgery in beagles. Acta Odontol Scand 1987; 45:141-146.
44. Lafferty A, Gher ME, Gray JI. Comparative SEM study on the effect of acid etching with tetracycline HCl or citric acid on instrumented periodontally-involved human root surfaces. J Periodontol 1993;64:689-693.
45. Stabholz A, Kettering J, Aprecio R, Zimmerman G, Baker PJ, Wikesjö UME. Retention of antimicrobial activity by human root surfaces after in situ subgingival irrigation with tetracycline HCl or chlorhexidine. J Periodontol 1993;64:137-141.
46. Stabholz A, Kettering J, Aprecio R, Zimmerman G, Baker PJ, Wikesjö UME. Antimicrobial properties of human dentin impregnated with tetracycline HCl or chlorhexidine. An in vitro study. J Clin Periodontol 1993;20:557-562.
47. Sterrett JD, Simons J, Whitford G, Russell CM. Tetracycline demineralization of dentin: The effects of concentration and application time. J Clin Periodontol 1997; 24:457-463.
48. Trombelli L, Scabbia A, Wikesjö UME, Calura G. Fibrin glue application in conjunction with tetracycline root conditioning and coronally positioned flap procedure in the treatment of human gingival recession defects. J Clin Periodontol 1996;23:861-867.
49. Wikesjö UME, Claffey N, Christersson LA, et al. Repair of periodontal furcation defects in beagle dogs following reconstructive surgery including root surface demineralization with tetracycline hydrochloride and topical fibronectin application. J Clin Periodontol 1988;15:73-80.
50. Ben-Yehouda, A. Progressive cervical root resorption related to tetracycline root conditioning. J Periodontol 1997;68:432-435.
51. Dyer BL, Caffesse RG, Nasjleti CE, Morrison EC. Guided tissue regeneration with dentin biomodification. J Periodontol 1993;64:1052-1060.