Histiocytoid breast carcinoma: Solid variant of invasive lobular carcinoma with decreased expression of both E-cadherin and CD44 epithelial variant

Pathology International

Volumn 55, Issue 6, 2005, Pages 353-359

  Fujiwara, Masachika ^a   Horiguchi, Miwa ^a   Mori, Satoshi ^a   Yokoyama, Koichi ^a   Horiguchi, Hisashi ^b   Fukazawa, Masakatsu ^c   Fujiwara, Hiromi ^c   Yano, Yukiko ^d   Satoh, Hiroaki ^d   Kamma, Hiroshi ^e  

^a Kensei General Hospital   (Japan)

^b Hitachi Mito General Hospital   (Japan)

^c UNIVERSITY OF TSUKUBA HOSPITAL   (Japan)

^d UNIVERSITY OF TSUKUBA   (Japan)

^e KYORIN UNIVERSITY   (Japan)

Author keywords

Aspiration cytology; Breast; CD44 epithelial variant; E cadherin; Histiocytoid carcinoma

Indexed keywords

CD44V ANTIGEN; CD44V10 ANTIGEN; CD44V8 ANTIGEN; CELL ADHESION MOLECULE; HERMES ANTIGEN; UNCLASSIFIED DRUG; UVOMORULIN;

AGED; ARTICLE; ASPIRATION BIOPSY; BREAST CARCINOMA; CANCER INVASION; CASE REPORT; FEMALE; GENE EXPRESSION; HISTIOCYTE; HISTIOCYTOSIS; HUMAN; IMMUNOHISTOCHEMISTRY; LUNG CARCINOMA; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AGED; ALTERNATIVE SPLICING; ANTIGENS, CD44; BREAST NEOPLASMS; CADHERINS; CARCINOMA, LOBULAR; FEMALE; HISTIOCYTES; HUMANS; IMMUNOHISTOCHEMISTRY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 21344459284     PISSN: 13205463     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1827.2005.01836.x     Document Type: Article

References (36)

1. Hood CI, Font RL, Zimmerman LE. Metastatic mammary carcinoma in the eyelid with histiocytoid appearance. Cancer 1973; 31: 793-800.
2. Filotico M, Trabucco M, Gallone D, Buonsanto A, Senatore S. Histiocytoid carcinoma of the breast. A problem of differential diagnosis for the pathologist. Report of a case. Pathologica 1983; 75: 429-33.
3. Eusebi V, Betts C, Haagensen DE Jr, Gugliotta P, Bussolati G, Azzopardi JG. Apocrine differentiation in lobular carcinoma of the breast: A morphologic, immunologic, and ultrastructural study. Hum Pathol 1984; 15: 134-40.
4. Dabski K, Milgrom H, Stoll HL Jr. Breast carcinoma metastatic to eyelids: Case report and review of the literature. J Surg Oncol 1985; 29: 233-6.
5. Allenby PA, Chowdhury LN. Histiocytic appearance of metastatic lobular breast carcinoma. Arch Pathol Lab Med 1986; 110:759-60.
6. Walford N, ten Velden J. Histiocytoid breast carcinoma: An apocrine variant of lobular carcinoma. Histopathology 1989; 14: 515-22.
7. Kitamura H, Kitamura H, Shimizu S, Matsukawa H, Arita E. Histiocytoid breast carcinoma: A case report with immunohistochemical and ultrastructural studies. Breast Cancer 1996; 3: 57-63.
8. Shimizu S, Kitamura H, Ito T, Nakamura T, Fujisawa J, Matsukawa H. Histiocytoid breast carcinoma: Histological, immunohistochemical, ultrastructural, cytological and clinicopathological studies. Pathol Int 1998; 48: 549-56.
9. Senatore S, Trabucco M, Gallone D, Filotico M. Metastatic histiocytoid carcinoma of the breast. Immunocytochemical report of a case. Pathologica 1986; 78: 71-8.
10. Eusebi V, Foschini MP, Bussolati G, Rosen PP. Myoblastomatoid (histiocytoid) carcinoma of the breast. A type of apocrine carcinoma. Am J Surg Pathol 1995; 19: 553-62.
11. Cohen H, Szvalb S, Bickel A, Maly B, Munichor M. Myoblastomatoid carcinoma of the breast: An unusual variant of apocrine carcinoma: report of a case with fine-needle aspiration cytology and immunohistochemical study. Diagn Cytopathol 1997; 16: 145-8.
12. Gupta D, Croitoru CM, Ayala AG, Sahin AA, Middleton LP. E-cadherin immunohistochemical analysis of histiocytoid carcinoma of the breast. Ann Diagn Pathol 2002; 6: 141-7.
13. Reis-Filho JS, Fulford LG, Freeman A, Lakhani SR. Pathologic quiz case: A 93-year-old woman with an enlarged and tender left breast. Histiocytoid variant of lobular breast carcinoma. Arch Pathol Lab Med 2003; 127: 1626-8.
14. Mazoujian G, Pinkus GS, Davis S, Haagensen DE Jr. Immunohistochemistry of a gross cystic disease fluid protein (GCDFP-15) of the breast. A marker of apocrine epithelium and breast carcinomas with apocrine features. Am J Pathol 1983; 110: 105-12.
15. Eusebi V, Millis RR, Cattani MG, Bussolati G, Azzopardi JG. Apocrine carcinoma of the breast. A morphologic and immunocytochemical study. Am J Pathol 1986; 123: 532-41.
16. Jackson DG, Buckley J, Bell JI. Multiple variants of the human lymphocyte homing receptor CD44 generated by insertions at a single site in the extracellular domain. J Biol Chem 1992; 267: 4732-9.
17. Screaton GR, Bell MV, Jackson DG, Cornells FB, Gerth U, Bell Jl. Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons. Proc Natl Acad Sci USA 1992; 89: 12160-4.
18. Stamenkovic I, Aruffo A, Amiot M, Seed B. The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate-bearing cells. EMBO J 1991; 10: 343-8.
19. Okamoto I, Morisaki T, Sasaki J et al. Molecular detection of cancer cells by competitive reverse transcription-polymerase chain reaction analysis of specific CD44 variant RNAs. J Natl Cancer Inst 1998; 90: 307-15.
20. Rodriguez C, Monges G, Rouanet P, Dutrillaux B, Lefrancois D, Theillet C. CD44 expression patterns in breast and colon tumors: A PCR-based study of splice variants. Int J Cancer 1995; 64: 347-54.
21. Lyzak JS, Yaremko ML, Recant W, Baunoch DA, Joseph L. Role of CD44 in nonpalpable T1a and T1b breast cancer. Hum Pathol 1997; 28: 772-8.
22. Kinoshita J, Haga S, Shimizu T, Imamura H, Watanabe O, Kajiwara T. The expression of variant exon v7-v8 CD44 antigen in relation to lymphatic metastasis of human breast cancer. Breast Cancer Res Treat 1999; 53: 177-83.
23. Eisenberg BL, Bagnall JW, Harding CT III. Histiocytoid carcinoma: A variant of breast cancer. J Surg Oncol 1986; 31: 271-4.
24. Cangiarella J, O'Connell Mazzei E, Weg N, Limaye A, Waisman J. Aspiration biopsy in a case of apocrine adenocarcinoma with foam cells (myoblastomatoid or histiocytoid adenocarcinoma). Diagn Cytopathol 2002; 26: 320-23.
25. Mazoujian G, Bodian C, Haagensen DE Jr, Haagensen CD. Expression of GCDFP-15 in breast carcinomas. Relationship to pathologic and clinical factors. Cancer 1989; 63: 2156-61.
26. Raju U, Ma CK, Shaw A. Signet ring variant of lobular carcinoma of the breast: A clinicopathologic and immunohistochemical study. Mod Pathol 1993; 6: 516-20.
27. Sapino A, Righi L, Cassoni P, Papotti M, Gugliotta P, Bussolati G. Expression of apocrine differentiation markers in neuroendocrine breast carcinomas of aged women. Mod Pathol 2001; 14: 768-76.
28. Takeichi M. Morphogenetic roles of classic cadherins. Curr Opin Cell Biol 1995; 7: 619-27.
29. Nelson WJ. Regulation of cell adhesion and development of epithelial cell surface polarity. Curr Top Membranes 1994; 41: 123-42.
30. Gumbiner BM. Cell adhesion: The molecular basis of tissue architecture and morphogenesis. Cell 1996; 84: 345-57.
31. Rasbridge SA, Gillett CE, Sampson SA, Walsh FS, Millis RR. Epithelial (E-) and placental (P-) cadherin cell adhesion molecule expression in breast carcinoma. J Pathol 1993; 169: 245-50.
32. Gamallo C, Palacios J, Suarez A et al. Correlation of E-cadherin expression with differentiation grade and histological type in breast carcinoma. Am J Pathol 1993; 142: 987-93.
33. Moll R, Mitze M, Frixen UH, Birchmeier W. Differential loss of E-cadherin expression in infiltrating ductal and lobular breast carcinomas. Am J Pathol 1993; 143: 1731-42.
34. Fechner RE. Histologic variants of infiltrating lobular carcinoma of the breast. Hum Pathol 1975; 6: 373-8.
35. Leach C, Howell LP. Cytodiagnosis of classic lobular carcinoma and its variants. Acta Cytol 1992; 36: 199-202.
36. Greeley CF, Frost AR. Cytologic features of ductal and lobular carcinoma in fine needle aspirates of the breast. Acta Cytol 1997; 41: 333-40.