Chemistry of N-phosphorylated nitrogen mustards: The effect of a second nitrogen substituent at phosphorus on the stability of the system

Phosphorus, Sulfur and Silicon and Related Elements

Volumn 108, Issue 1-4, 1996, Pages 155-168

  Wan, Huijie ^a   Modro, Tomasz A ^a  

^a UNIVERSITY OF PRETORIA   (South Africa)

Author keywords

Dimethyl N,N diethyl phosphoramidate; Methyl N,N,N ,N tetraetnylphosphordiamidate; Methyl N,N diethyl N ,N bis(2 chloroethyl)phosphordiamidate; Methyl N,N diethyl N ,N bis 2 (mercaptophenyl)ethyl phosphordiamidate

Indexed keywords

EID: 21344451821     PISSN: 10426507     EISSN: None     Source Type: Journal    
DOI: 10.1080/10426509608029648     Document Type: Article

References (13)

1. C. le Roux, A. M. Modro and T. A. Modro, J. Org. Chem., 60, 3832 (1995).
2. W. J. Stec, in "Organophosphorus Chemistry," The Royal Society of Chemistry, London, Vol. 13, Chap. 8, 1982.
3. See, for example: C. C. Orji and A. G. Pinkus, OPPI Briefs, 26, 691 (1994).
4. L. D. Quin, J. Szewczyk, K. M. Szewczyk and A. T. McPhail, J. Org. Chem., 51, 3341 (1986); L. D. Quin, N. D. Sadanani, C. Bourdieu, X.-P. Wu, G. S. Quin and R. Bodalski, Phosphorus, Sulfur, and Silicon, 49/50, 313 (1990); L. D. Quin, C. Bourdieu and G. S. Quin, Phosphorus, Sulfur, and Silicon, 63, 349 (1991).
5. L. D. Quin, J. Szewczyk, K. M. Szewczyk and A. T. McPhail, J. Org. Chem., 51, 3341 (1986); L. D. Quin, N. D. Sadanani, C. Bourdieu, X.-P. Wu, G. S. Quin and R. Bodalski, Phosphorus, Sulfur, and Silicon, 49/50, 313 (1990); L. D. Quin, C. Bourdieu and G. S. Quin, Phosphorus, Sulfur, and Silicon, 63, 349 (1991).
6. L. D. Quin, J. Szewczyk, K. M. Szewczyk and A. T. McPhail, J. Org. Chem., 51, 3341 (1986); L. D. Quin, N. D. Sadanani, C. Bourdieu, X.-P. Wu, G. S. Quin and R. Bodalski, Phosphorus, Sulfur, and Silicon, 49/50, 313 (1990); L. D. Quin, C. Bourdieu and G. S. Quin, Phosphorus, Sulfur, and Silicon, 63, 349 (1991).
7. R. S. Edmundson, in "CRC Handbook of Phosphorus-31 Nuclear Magnetic Resonance Data," Ed. J. C. Tebby, CRC Press, Boca Raton, 1991, p. 268.
8. A. M. Modro and T. A. Modro, J. Phys. Org. Chem., 2, 377 (1989).
9. G. W. Daub and E. E. van Tamelen, J. Am. Chem. Soc., 99, 3526 (1977).
10. G. W. Klump, "Reactivity in Organic Chemistry," Wiley-Interscience, New York, 1982, Chap. 3.2.
11. M. Colvin, M. N. Brundrett, N. Kan, I. Jardine and C. Fenselau, Cancer Res., 36, 1121 (1976).
12. O. M. Friedman, Cancer Treat. Rep., 51, 347 (1967).
13. C. Mcguigan and P. Narashiman, Synthesis, 311 (1993).