Management of severe refractory adult autoimmune enteropathy with infliximab and tacrolimus

Digestion

Volumn 71, Issue 3, 2005, Pages 141-144

  Von Hahn, Thomas ^a   Stopik, Dieter ^a   Koch, Martin ^a   Wiedenmann, Bertram ^a   Dignass, Axel ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Autoimmune enteropathy; Infliximab; Tacrolimus; Tumor necrosis factor

Indexed keywords

AZATHIOPRINE; INFLIXIMAB; PREDNISOLONE; TACROLIMUS;

ADULT; ARTICLE; AUTOIMMUNE ENTEROPATHY; CASE REPORT; CLINICAL FEATURE; DIARRHEA; DISEASE SEVERITY; DRUG WITHDRAWAL; ENTEROPATHY; HUMAN; HUMAN TISSUE; HYPERSENSITIVITY REACTION; INTESTINE BIOPSY; LABORATORY DIAGNOSIS; MALE; PRIORITY JOURNAL; REMISSION; WEIGHT REDUCTION;

ADMINISTRATION, ORAL; ADULT; ANTIBODIES, MONOCLONAL; AUTOIMMUNE DISEASES; BIOPSY; DRUG THERAPY, COMBINATION; ENDOSCOPY, GASTROINTESTINAL; FOLLOW-UP STUDIES; GASTROINTESTINAL AGENTS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFUSIONS, INTRAVENOUS; INTESTINAL DISEASES; INTESTINAL MUCOSA; MALE; SEVERITY OF ILLNESS INDEX; TACROLIMUS; TREATMENT OUTCOME;

EID: 21344439111     PISSN: 00122823     EISSN: None     Source Type: Journal    
DOI: 10.1159/000084648     Document Type: Article

References (18)

1. Hill SM, Milla PJ, Bottazzo GF, et al: Autoimmune enteropathy and colitis: Is there a generalised autoimmune gut disorder? Gut 1991;32: 36-42.
2. Corazza GR, Biagi F, Volta U, et al: Autoimmune enteropathy and villous atrophy in adults. Lancet 1997;350:106-109.
3. Mirakian R, Richardson A, Milla PJ, et al: Protracted diarrhoea of infancy: Evidence in support of an autoimmune variant. Br Med J (Clin Res Ed) 1986;293:1132-1136.
4. Unsworth DJ, Walker-Smith JA: Autoimmunity in diarrhoeal disease. J Pediatr Gastroenterol Nutr 1985;4:375-380.
5. Carroccio A, Volta U, Di Prima L, et al: Autoimmune enteropathy and colitis in an adult patient. Dig Dis Sci 2003;48:1600-1606.
6. Bousvaros A, Leichtner AM, Book L, et al: Treatment of pediatric autoimmune enteropathy with tacrolimus (FK506). Gastroenterology 1996;111:237-243.
7. Oliva-Hemker MM, Loeb DM, Abraham SC, et al: Remission of severe autoimmune enteropathy after treatment with high-dose cyclophosphamide. J Pediatr Gastroenterol Nutr 2003;36:639-643.
8. Quiros-Tejeira RE, Ament ME, Vargas JH: Induction of remission in a child with autoimmune enteropathy using mycophenolate mofetil. J Pediatr Gastroenterol Nutr 2003;36: 482-485.
9. Seidman EG, Lacaille F, Russo P, et al: Successful treatment of autoimmune enteropathy with cyclosporine. J Pediatr 1990;117:929-932.
10. Vanderhoof JA, Young RJ: Autoimmune enteropathy in a child: Response to infliximab therapy. J Pediatr Gastroenterol Nutr 2002;34: 312-316.
11. Daum S, Sahin E, Jansen A, et al: Adult autoimmune enteropathy treated successfully with tacrolimus. Digestion 2003;68:86-90.
12. Gillett HR, Arnott ID, McIntyre M, et al: Successful infliximab treatment for steroid-refractory celiac disease: A case report. Gastroenterology 2002;122:800-805.
13. Targan SR, Hanauer SB, van Deventer SJ, et al: A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. N Engl J Med 1997;337:1029-1035.
14. Mirakian R, Collins P, Bottazzo GF: Autoimmune enteropathy in adults. Lancet 1997;350: 959-960.
15. Murch SH, Fertleman CR, Rodrigues C, et al: Autoimmune enteropathy with distinct mucosal features in T-cell activation deficiency: The contribution of T cells to the mucosal lesion. J Pediatr Gastroenterol Nutr 1999;28:393-399.
16. Lugering A, Schmidt M, Lugering N, et al: Infliximab induces apoptosis in monocytes from patients with chronic active Crohn's disease by using a caspase-dependent pathway. Gastroenterology 2001;121:1145-1157.
17. ten Hove T, van Montfrans C, Peppelenbosch MP, et al: Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease. Gut 2002;50:206-211.
18. Oberhuber G, Caspary WF, Kirchner T, Borchard F, Stolte M: Empfehlungen zur Sprue-/ Zöliakiediagnostik. Pathologe 2001;22:72-81.