-
1
-
-
0023849455
-
Autocrine generation and. requirement of BSF-2/IL-6 for human multiple myelomas
-
Kawano M, Hirano T, Matsuda T, Taga T, Horii Y, Iwato K, et al. Autocrine generation and. requirement of BSF-2/IL-6 for human multiple myelomas. Nature 1988; 332:83-5.
-
(1988)
Nature
, vol.332
, pp. 83-85
-
-
Kawano, M.1
Hirano, T.2
Matsuda, T.3
Taga, T.4
Horii, Y.5
Iwato, K.6
-
2
-
-
0037377190
-
Humanized anti-interleukin-6 receptor monoclonal antibody induced apoptosis of fresh and cloned human myeloma cells in vitro
-
Hirata T, Shimazaki C, Sumikuma T, Ashihara E, Goto H, Inaba T, et al. Humanized anti-interleukin-6 receptor monoclonal antibody induced apoptosis of fresh and cloned human myeloma cells in vitro. Leuk Res 2003; 27:343-9.
-
(2003)
Leuk Res
, vol.27
, pp. 343-349
-
-
Hirata, T.1
Shimazaki, C.2
Sumikuma, T.3
Ashihara, E.4
Goto, H.5
Inaba, T.6
-
3
-
-
0142250392
-
Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: A review of the rationale and clinical evidence
-
Trikha M, Corringham R, Klein B, Rossi JF. Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence. Clin Cancer Res 2003; 9:4653-65.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 4653-4665
-
-
Trikha, M.1
Corringham, R.2
Klein, B.3
Rossi, J.F.4
-
4
-
-
0024419152
-
Production of cytokines by bone marrow cells obtained from patients with multiple myeloma
-
Lichtenstein A, Berenson J, Norman D, Chang M P, Carlile A. Production of cytokines by bone marrow cells obtained from patients with multiple myeloma. Blood 1989; 74:1266-73.
-
(1989)
Blood
, vol.74
, pp. 1266-1273
-
-
Lichtenstein, A.1
Berenson, J.2
Norman, D.3
Chang, M.P.4
Carlile, A.5
-
5
-
-
0034893680
-
Expression of IL-6 and IL-6 receptors by circulating clonotypic B cells in multiple myeloma: Potential for autocrine and paracrine networks
-
Szczepek AJ, Belch AR, Pilarski LM. Expression of IL-6 and IL-6 receptors by circulating clonotypic B cells in multiple myeloma: potential for autocrine and paracrine networks. Exp Hematol 2001; 29:1076-81.
-
(2001)
Exp Hematol
, vol.29
, pp. 1076-1081
-
-
Szczepek, A.J.1
Belch, A.R.2
Pilarski, L.M.3
-
6
-
-
0035863942
-
Autocrine interleukin-6 production and highly malignant multiple myeloma: Relation with resistance to drug-induced apoptosis
-
Frassanito MA, Cusmai A, Iodice G, Dammacco F. Autocrine interleukin-6 production and highly malignant multiple myeloma: relation with resistance to drug-induced apoptosis. Blood 2001; 97:483-9.
-
(2001)
Blood
, vol.97
, pp. 483-489
-
-
Frassanito, M.A.1
Cusmai, A.2
Iodice, G.3
Dammacco, F.4
-
7
-
-
9444235088
-
Co-operative functions between nuclear factors NFκB and CCAT/enhancer-binding protein-beta (C/EBP-β) regulate the IL-6 promoter in autocrine human prostate cancer cells
-
In press
-
Xiao W, Hodge D, Wang L, Yang X, Zhang X, Farrar W. Co-operative functions between nuclear factors NFκB and CCAT/enhancer-binding protein-beta (C/EBP-β) regulate the IL-6 promoter in autocrine human prostate cancer cells. Prostate 2004; In press.
-
(2004)
Prostate
-
-
Xiao, W.1
Hodge, D.2
Wang, L.3
Yang, X.4
Zhang, X.5
Farrar, W.6
-
8
-
-
0033121314
-
Role of NF-κB in the rescue of multiple myeloma cells from glucocorticoid-induced apoptosis by bcl-2
-
Feinman R, Koury J, Thames M, Barlogie B, Epstein J, Siegel D S. Role of NF-κB in the rescue of multiple myeloma cells from glucocorticoid-induced apoptosis by bcl-2. Blood 1999; 93:3044-52.
-
(1999)
Blood
, vol.93
, pp. 3044-3052
-
-
Feinman, R.1
Koury, J.2
Thames, M.3
Barlogie, B.4
Epstein, J.5
Siegel, D.S.6
-
9
-
-
18544367201
-
NF-κB as a therapeutic target in multiple myeloma
-
Hideshima T, Chauhan D, Richardson P, Mitsiades C, Mitsiades N, Hayashi T, et al. NF-κB as a therapeutic target in multiple myeloma. J Biol Chem 2002; 277:16639-47.
-
(2002)
J Biol Chem
, vol.277
, pp. 16639-16647
-
-
Hideshima, T.1
Chauhan, D.2
Richardson, P.3
Mitsiades, C.4
Mitsiades, N.5
Hayashi, T.6
-
10
-
-
0035139792
-
Therapeutic potential of inhibition of the NF-κB pathway in the treatment of inflammation and cancer
-
Yamamoto Y, Gaynor R B. Therapeutic potential of inhibition of the NF-κB pathway in the treatment of inflammation and cancer. J Clin Invest 2001; 107:135-42.
-
(2001)
J Clin Invest
, vol.107
, pp. 135-142
-
-
Yamamoto, Y.1
Gaynor, R.B.2
-
11
-
-
0035933772
-
Inhibition of NF-κB activity by thalidomide through suppression of IκB kinase activity
-
Keifer J A, Guttridge D C, Ashburner B P, Baldwin A S, Jr. Inhibition of NF-κB activity by thalidomide through suppression of IκB kinase activity. J Biol Chem 2001; 276:22382-7.
-
(2001)
J Biol Chem
, vol.276
, pp. 22382-22387
-
-
Keifer, J.A.1
Guttridge, D.C.2
Ashburner, B.P.3
Baldwin Jr., A.S.4
-
12
-
-
21244489945
-
NK-κB activates IL-6 expression through cooperation with c-Jun and IL6-AP1 site, but is independent of its IL6-NFκB regulatory site in autocrine human multiple myeloma cells
-
In press
-
Xiao W, Hodge D, Wang L, Yang X, Zhang X, Farrar W. NK-κB activates IL-6 expression through cooperation with c-Jun and IL6-AP1 site, but is independent of its IL6-NFκB regulatory site in autocrine human multiple myeloma cells. Cancer Biol Ther 2004; In press.
-
(2004)
Cancer Biol Ther
-
-
Xiao, W.1
Hodge, D.2
Wang, L.3
Yang, X.4
Zhang, X.5
Farrar, W.6
-
13
-
-
4544342570
-
Nuclear factor-kappaB: The enemy within
-
Aggarwal BB. Nuclear factor-kappaB: the enemy within. Cancer Cell 2004; 6:203-8.
-
(2004)
Cancer Cell
, vol.6
, pp. 203-208
-
-
Aggarwal, B.B.1
-
14
-
-
0036007233
-
Regulation of TNF-α-induced IL-6 production in MG-63 human osteoblast-like cells
-
Webb S J, McPherson J R, Pahan K, Koka S. Regulation of TNF-α-induced IL-6 production in MG-63 human osteoblast-like cells. J Dent Res 2002; 81:17-22.
-
(2002)
J Dent Res
, vol.81
, pp. 17-22
-
-
Webb, S.J.1
McPherson, J.R.2
Pahan, K.3
Koka, S.4
-
15
-
-
0036040166
-
Transcriptional control of the inflammatory response: A role for the CREB-binding protein (CBP)
-
Matt T. Transcriptional control of the inflammatory response: a role for the CREB-binding protein (CBP). Acta Med Austriaca 2002; 29:77-9.
-
(2002)
Acta Med Austriaca
, vol.29
, pp. 77-79
-
-
Matt, T.1
-
16
-
-
0028033909
-
Heterogeneous chromosomal aberrations generate 3′ truncations of the NFKB2/lyt-10 gene in lymphoid malignancies
-
Migliazza A, Lombardi L, Rocchi M, Trecca D, Chang CC, Antonacci R, et al. Heterogeneous chromosomal aberrations generate 3′ truncations of the NFKB2/lyt-10 gene in lymphoid malignancies. Blood 1994; 84:3850-60.
-
(1994)
Blood
, vol.84
, pp. 3850-3860
-
-
Migliazza, A.1
Lombardi, L.2
Rocchi, M.3
Trecca, D.4
Chang, C.C.5
Antonacci, R.6
-
17
-
-
11144355586
-
BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone
-
Moreaux J, Legouffe E, Jourdan E, Quittet P, Reme T, Lugagne C, et al. BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone. Blood 2004; 103:3148-57.
-
(2004)
Blood
, vol.103
, pp. 3148-3157
-
-
Moreaux, J.1
Legouffe, E.2
Jourdan, E.3
Quittet, P.4
Reme, T.5
Lugagne, C.6
-
18
-
-
0036546501
-
NF-κB in cancer: From innocent bystander to major culprit
-
Karin M, Cao Y, Greten F R, Li Z W. NF-κB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2002; 2:301-10.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 301-310
-
-
Karin, M.1
Cao, Y.2
Greten, F.R.3
Li, Z.W.4
-
19
-
-
0037973279
-
A phase 2 study of bortezomib in relapsed, refractory myeloma
-
Richardson P G, Barlogie B, Berenson J, Singhai S, Jagannath S, Irwin D, et al. A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med 2003; 348:2609-17.
-
(2003)
N Engl J Med
, vol.348
, pp. 2609-2617
-
-
Richardson, P.G.1
Barlogie, B.2
Berenson, J.3
Singhai, S.4
Jagannath, S.5
Irwin, D.6
-
20
-
-
0032748385
-
Antitumor activity of thalidomide in refractory multiple myeloma
-
Singhal S, Mehta J, Desikan R, Ayers D, Roberson P, Eddlemon P, et al. Antitumor activity of thalidomide in refractory multiple myeloma. N Engl J Med 1999; 341:1565-71.
-
(1999)
N Engl J Med
, vol.341
, pp. 1565-1571
-
-
Singhal, S.1
Mehta, J.2
Desikan, R.3
Ayers, D.4
Roberson, P.5
Eddlemon, P.6
-
21
-
-
0036843032
-
Combination therapy with thalidomide plus dexamethasone for newly diagnosed myeloma
-
Rajkumar SV, Hayman S, Gertz MA, Dispenzieri A, Lacy M Q, Greipp PR, et al. Combination therapy with thalidomide plus dexamethasone for newly diagnosed myeloma. J Clin Oncol 2002; 20:4319-23.
-
(2002)
J Clin Oncol
, vol.20
, pp. 4319-4323
-
-
Rajkumar, S.V.1
Hayman, S.2
Gertz, M.A.3
Dispenzieri, A.4
Lacy, M.Q.5
Greipp, P.R.6
|