Aging and transplant arteriosclerosis in absence of alloreactivity and immunosuppressive drugs in a rat aortic model: Recipient age's contribution

Transplantation

Volumn 79, Issue 12, 2005, Pages 1683-1690

  Calfa, Marian ^a   Aïtouche, Abdelouahab ^a   Vazquez Padron, Roberta I ^a   Gay Rabinstein, Carlota ^a   Lasko, David ^a   Badell, John ^a   Farji, Arie ^a   El Haddad, Ahmed ^a   Liotta, Carlos ^a   Louis, Louis B ^a   Simmonds, Alric ^a   Pestana, Ivo A ^a   Pang, Manhui ^a   Li, Sen ^a   Pham, Si M ^a,b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b Division of Transplantation   (United States)

Author keywords

Aorta artery; Arteriosclerosis; Graft transplant; Old aging young; Organ procurement; Recipient donor age

Indexed keywords

COLLAGEN; ELASTIN; IMMUNOSUPPRESSIVE AGENT;

AGE; AGING; ALLOIMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; AORTA GRAFT; ARTERIOSCLEROSIS; ARTERY INTIMA PROLIFERATION; ARTICLE; BLOOD VESSEL INJURY; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; ISCHEMIA; NONHUMAN; PRIORITY JOURNAL; RAT;

AGING; ANIMALS; AORTA; AORTA, THORACIC; ARTERIOSCLEROSIS; DISEASE MODELS, ANIMAL; FEMALE; GRAFT SURVIVAL; IMMUNOSUPPRESSIVE AGENTS; RATS; RATS, INBRED F344; TRANSPLANTATION, HOMOLOGOUS; TRANSPLANTATION, ISOGENEIC; TUNICA INTIMA;

EID: 21244463496     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000163467.93783.C8     Document Type: Article

References (40)

1. Oppenheimer F, Aljama P, Asensio Peinado C, et al. The impact of donor age on the results of renal transplantation. Nephrol Dial Transplant 2004; 19 (suppl 3): iii11.
2. Terasaki PI, Gjertson DW, Cecka JM, et al. Significance of the donor age effect on kidney transplants. Clin Transplant 1997; 11: 366.
3. Blanche C, Kamlot A, Blanche DA, et al. Heart transplantation with donors fifty years of age and older. J Thorac Cardiovasc Surg 2002; 123: 810.
4. Stemerman MB, Weinstein R, Rowe JW, et al. Vascular smooth muscle cell growth kinetics in vivo in aged rats. Proc Natl Acad Sci USA 1982; 79: 3863.
5. Spagnoli LG, Sambuy Y, Palmieri G, et al. Age-related modulation of vascular smooth muscle cells proliferation following arterial wall damage. Artery 1985; 13: 187.
6. Hariri RJ, Alonso DR, Hajjar DP, et al. Aging and arteriosclerosis. I. Development of myointimal hyperplasia after endothelial injury. J Exp Med 1986; 164: 1171.
7. Ciancio G, Burke GW, Gaynor JJ, et al. A randomized long-term trial of tacrolimus/sirolimus versus tacrolimus/mycophenolate mofetil versus cyclosporine (NEORAL)/sirolimus in renal transplantation. II. Survival, function, and protocol compliance at 1 year. Transplantation 2004; 77: 252.
8. Waller JR, Brook NR, Bicknell GR, et al. Differential effects of modern immunosuppressive agents on the development of intimal hyperplasia. Transpl Int 2004; 17: 9.
9. Cecka JM. The UNOS Scientific Renal Transplant Registry. Clin Transpl 1999; 1.
10. Liu S, Lutz J, Antus B, et al. Recipient age and weight affect chronic renal allograft rejection in rats. J Am Soc Nephrol 2001; 12: 1742.
11. Moreso F, Ortega F, Mendiluce A. Recipient age as a determinant factor of patient and graft survival. Nephrol Dial Transplant 2004; 19 (suppl 3): iii16.
12. Indolfi C, Piscione F, Ceravolo R, et al. Limb vasoconstriction after successful angioplasty of the left anterior descending coronary artery. Circulation 1995; 92: 2109.
13. Capron L, Bruneval P. Influence of applied stress on mitotic response of arteries to injury with a balloon catheter: quantitative study in rat thoracic aorta. Cardiovasc Res 1989; 23: 941.
14. Masseroli M, O'Valle F, Andujar M, et al. Design and validation of a new image analysis method for automatic quantification of interstitial fibrosis and glomerular morphometry. Lab Invest 1998; 78: 511.
15. Fukada J, Schena S, Tack I, et al. FK409, a spontaneous nitric oxide releaser, attenuates allograft vasculopathy in a rat aortic transplant model. Circ Res 2000; 87: 66.
16. Carayon P, Bord A. Identification of DNA-replicating lymphocyte subsets using a new method to label the bromo-deoxyuridine incorporated into the DNA. J Immunol Methods 1992; 147: 225.
17. Akyurek LM, Johnsson C, Lange D, et al. Tolerance induction ameliorates allograft vasculopathy in rat aortic transplants. Influence of Fas-mediated apoptosis. J Clin Invest 1998; 101: 2889.
18. Muramatsu K, Kurokawa Y, Ihara K, et al. Behavior of male-specific minor histocompatibility antigen in skin and limb transplantation. J Surg Res 2003; 115: 106.
19. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993; 362: 801.
20. Haudenschild CC, Schwartz SM. Endothelial regeneration. II. Restitution of endothelial continuity. Lab Invest 1979; 41: 407.
21. Forrester JS, Fishbein M, Helfant R, et al. A paradigm for restenosis based on cell biology: clues for the development of new preventive therapies. J Am Coll Cardiol 1991; 17: 758.
22. McCaffrey TA, Agarwal LA, Weksler BB. A rapid fluorometric DNA assay for the measurement of cell density and proliferation in vitro. In Vitro Cell Dev Biol 1988; 24: 247.
23. Bierman EL, Albers JJ, Chait A. Effect of donor age on the binding and degradation of low density lipoproteins by cultured human arterial smooth muscle cells. J Gerontol 1979; 34: 483.
24. Grunwald J, Mey J, Schonleben W, et al. Cultivated human arterial smooth muscle cells. The effect of donor age, blood pressure, diabetes and smoking on in vitro cell growth. Pathol Biol 1983; 31: 819.
25. Bilato C, Crow MT. Atherosclerosis and the vascular biology of aging. Aging (Milano) 1996; 8: 221.
26. Gregory CR, Huie P, Billingham ME, et al. Rapamycin inhibits arterial intimal thickening caused by both alloimmune and mechanical injury. Its effect on cellular, growth factor, and cytokine response in injured vessels. Transplantation 1993; 55: 1409.
27. Vazquez-Padron RI, Lasko D, Louis LB, et al. Aging exacerbates neointimal formation, increases the proliferation, and reduces susceptibility to apoptosis, of vascular smooth muscle cells in mice J Vasc Surg 2004; 40: 1199.
28. Fukagawa NK, Li M, Timblin CR, et al. Modulation of cell injury and survival by high glucose and advancing age. Free Radic Biol Med 2001; 31: 1560.
29. Wang E. Regulation of apoptosis resistance and ontogeny of age-dependent diseases. Exp Gerontol 1997; 32: 471.
30. Alexander RW. Atherosclerosis as disease of redox-sensitive genes. Trans Am Clin Climatol Assoc 1998; 109: 129; discussion 145.
31. Csiszar A, Ungvari Z, Koller A, et al. Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging. Physiol Genomics 2004; 17: 21.
32. Belmin J, Bernard C, Corman B, et al. Increased production of tumor necrosis factor and interleukin-6 by arterial wall of aged rats. Am J Physiol 1995; 268: H2288.
33. Li M, Mossman BT, Kolpa E, et al. Age-related differences in MAP kinase activity in VSMC in response to glucose or TNF-alpha. J Cell Physiol 2003; 197: 418.
34. Gaballa MA, Jacob CT, Raya TE, et al. Large artery remodeling during aging: biaxial passive and active stiffness. Hypertension 1998; 32: 437.
35. Li Z, Froehlich I, Galis ZS, et al. Increased expression of matrix metalloproteinase-2 in the thickened intima of aged rats. Hypertension 1999; 33: 116.
36. Chang KC, Hsu KL, Peng YI, et al. Aminoguanidine prevents age-related aortic stiffening in Fisher 344 rats: aortic impedance analysis. Br J Pharmacol 2001; 140: 107.
37. Wei JY, Mendelowitz D, Anastasi N, et al. Maintenance of carotid baroreflex function in advanced age in the rat. Am J Physiol 1986; 250: R1047.
38. Schwartz RS, Holmes DR Jr, Topol EJ. The restenosis paradigm revisited: an alternative proposal for cellular mechanisms [editorial]. J Am Coll Cardiol 1992; 20: 1284.
39. Han CI, Campbell GR, Campbell JH. Circulating bone marrow cells can contribute to neointimal formation. J Vasc Res 2001; 38: 113.
40. Shimizu K, Sugiyama S, Aikawa M, et al. Host bone-marrow cells are a source of donor intimal smooth- muscle-like cells in murine aortic transplant arteriopathy. Nat Med 2001; 7: 738.