Damage of cutaneous peripheral nervous system evolves differently according to the disease phase and subset of systemic sclerosis

Rheumatology

Volumn 44, Issue 5, 2005, Pages 607-613

  Manneschi, L Ibba ^a,c   Del Rosso, A ^a   Milia, A F ^a   Tani, A ^a   Nosi, D ^a   Pignone, A ^a   Generini, S ^a   Giacomelli, R ^b   Cerinic, M Matucci ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF L'AQUILA   (Italy)

^c Department of Anatomy Histology and Forensic Medicine ^*  (Italy)

Author keywords

Peripheral nervous system; Skin; Systemic sclerosis; Transmission electron microscopy

Indexed keywords

ADULT; ARTICLE; BLOOD VESSEL WALL; CLINICAL ARTICLE; CONTROLLED STUDY; DERMIS; DISEASE CLASSIFICATION; DISEASE COURSE; DISEASE SEVERITY; ENDOTHELIUM CELL; FEMALE; FIBROSIS; FOREARM; HUMAN; HUMAN TISSUE; HYPERTROPHY; INFLAMMATION; MALE; MICROVASCULATURE; NERVE FIBER; NERVOUS SYSTEM INJURY; PATHOGENESIS; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; SKIN BIOPSY; SKIN DEFECT; SKIN NERVE; SYSTEMIC SCLEROSIS; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE; BIOPSY; DIFFUSE SCLERODERMA; INNERVATION; LIMITED SCLERODERMA; MIDDLE AGED; PATHOLOGY; PERIPHERAL NEUROPATHY; SKIN;

ADULT; BIOPSY; DISEASE PROGRESSION; FEMALE; HUMANS; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; MIDDLE AGED; PERIPHERAL NERVOUS SYSTEM DISEASES; SCLERODERMA, DIFFUSE; SCLERODERMA, LIMITED; SCLERODERMA, SYSTEMIC; SKIN;

EID: 21244461966     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/keh559     Document Type: Article

References (42)

1. Clements PJ, Furst DE. Systemic sclerosis. Baltimore (MD): Williams & Wilkinson, 2003.
2. LeRoy EC, Black C, Fleishmajer R et al. Scleroderma (systemic sclerosis): Classification, subsets and pathogenesis. J Rheumatol 1988; 15:202-5.
3. Hashimoto K, Niizuma K. Skin pathology by light and electron microscopy. New York: Igaku-Shoin, 1983:62-70.
4. Trotta F, Biagini G, Cenacchi G et al. Microvascular changes in progressive systemic sclerosis: Immunohistochemical and ultrastructural study. Clin Exp Rheumatol 1984;2:209-15.
5. Prescott RJ, Freemont AJ, Jones CJP, Hoyland J, Fielding P. Sequential dermal microvascular and perivascular changes in the development of scleroderma. J Pathol 1992;166:255-63.
6. Von Bierbrauer A, Barth P, Willert J, Baerwald C, Mennel HD, Schmidt JA. Electron microscopy and capillaroscopically guided nailfold biopsy in connective tissue diseases: Detection of ultrastructural changes of the microcirculatory vessels. Br J Rheumatol 1998; 37:1272-8.
7. Badakov S. Ultrastructural changes of cutaneous nerves in scleroderma. Folia Med (Plovdiv) 1992;34:57-64.
8. Di Trapani G, Pocchiari M, Masullo C, Albanese A, Tulli A. Peripheral neuropathy in the course of progressive systemic sclerosis: Light and ultrastructural study. Ital J Neurol Sci 1982;3:341-8.
9. Matucci Cerinic M, Generini S, Pignone A, Casale R. The nervous system in systemic sclerosis (scleroderma). Clinical features and pathogenetic mechanism. Rheum Dis Clin North Am 1996; 22:879-91.
10. Kennedy WR, Wendelschafer-Crabb G. The innervation of human epidermis. J Neurol Sci 1993;115:184-90.
11. Hilliges M, Wang L, Johansson O. Ultrastructural evidence for nerve fibres within all vital layer of the human epidermis. J Invest Dermatol 1995;104:134-7.
12. Knupp-Oliveira S, Matucci-Cerinic M. Polyneuropathy as initial manifestation of systemic sclerosis (scleroderma). Scand J Rheumatol 1999;28:260-261.
13. Lori S, Matucci Cerinic M, Casale R et al. Peripheral nervous system involvement in systemic sclerosis: The median nerve as target structure. Clin Exp Rheumatol 1996;14:601-5.
14. Generini S, Fiori G, Moggi Pignone A, Matucci Cerinic M, Cagnoni M. Systemic sclerosis. A clinical overview. Adv Exp Med Biol 1999;455:73-83.
15. Bertinotti L, Bracci S, Nacci F et al. The autonomic nervous system in systemic sclerosis. A review. Clin Rheumatol 2004;23:1-5.
16. Ormea F. Comparative studies of the peripheral autonomous nervous system in diffuse sclerodermia and in connective tissue changed by various skin diseases. Dermatologica 1952;105:8-17.
17. Rossi R, Johansson O. Cutaneous innervation and the role of neuronal peptides in cutaneous inflammation: A minireview. Eur J Dermatol 1998;8:299-306.
18. Terenghi G, Bunker CB, Liu YF et al. Image analysis quantification of peptide-immunoreactive nerves in the skin of patients with Raynaud phenomenon and systemic sclerosis. J Pathol 1991;164: 245-52.
19. Kahaleh B, Matucci Cerinic M. Raynaud's phenomenon and scleroderma. Dysregulated neuroendothelial control of vascular tone. Arthritis Rheum 1995;38:1-4.
20. Lock G, Holtstege A, Lang B, Schoelmeric J. Gastrointestinal manifestation of progressive systemic sclerosis. Am J Gastroenterol 1997;92:763-71.
21. Franchini KG, Cowley AW. Autonomic control of cardiac function. In: Robertson D, Low PA, Polinski RJ, eds. Primer on the autonomic nervous system. San Diego, CA: Academic Press, 1996:42-9.
22. Bertinotti L, Pietrini U, Del Rosso A et al. The use of pupillometry in joint and connective tissue diseases. Ann NY Acad Sci 2002; 966:446-55.
23. Del Rosso A, Bertinotti L, Pietrini U et al. Pupillocynetic activity of substance P in systemic sclerosis. J Rheumatol 2003;30:1231-7.
24. Matucci-Cerinic M. D'Angelo S, Denton CP, Vlachoyiannopoulos P, Silver R. Assessment of lung involvement. Clin Exp Rheumatol 2003;21:S19-23.
25. Di Trapani G, Tulli A, La Cara A, Laurenzio P, Mazza S, David P. Peripheral neuropathy in the course of progressive systemic sclerosis: light and ultrastructural study. Acta Neuropathol (Berl) 1986;72: 103-10.
26. Medsger TA Jr, Steen VD. Classification, prognosis. In: Clements PJ, Furst DE, eds. Systemic sclerosis. Baltimore (MD): Williams & Wilkins. 1996:51-79.
27. The assessment of the patient with systemic sclerosis. Proceedings of a symposium, Portonovo (Italy), February 7-9 2002. Clin Exp Rheumatol 2003;21(Suppl. 29).
28. Cutolo M, Sulli A, Pizzorni C et al. Nailfold videocapillaroscopy assessment of microvascular damage in systemic sclerosis. J Rheumatol 2000;27:155-60.
29. Clements P, Lachenbruch P, Seibold J et al. Inter and intraobserver variability of total skin thickness score (modified Rodnan TSS) in systemic sclerosis. J Rheumatol 1995;22:1281-5.
30. Fernandez F, Ramires FJA, Arteaga E, Ianni BM, Dutra Oliveira Bonfa EF. Cardiac remodeling in patients with systemic sclerosis with no signs or symptoms of heart failure: An endomyocardial biopsy study. J Card Fail 2003;9:311-7.
31. Follansbee WP, Miller TR, Curtiss EI et al. A controlled clinico-pathologic study of myocardial fibrosis in systemic sclerosis (scleroderma). J Rheumatol 1990;17:656-62.
32. Malandrini A, Selvi E, Villanova M et al. Autonomic nervous system and smooth muscle cell involvement in systemic sclerosis: Ultrastructural study of three cases. J Rheumatol 2000; 27:1203-6.
33. Ibba Manneschi L, Del Rosso A, Pacini S, Tani A, Bechi P, Matucci Cerinic M. Ultrastructural study of the muscle coat of the gastric wall in a case of systemic sclerosis. Ann Rheum Dis 2002;61: 754-6.
34. Corbo M, Nemni R, Iannaccone S. Peripheral neuropathy in scleroderma. Clin Neuropathol 1993;12:63-7.
35. Sukenik S, Abarbanel JM, Buskila D, Potashnik G, Horowitz J. Impotence, carpal tunnel syndrome and peripheral neuropathy as presenting symptoms in progressive systemic sclerosis. J Rheumatol 1987;14:641-3.
36. Oddis CV, Eisenbeis CH Jr, Reidbord HE, Steen VD, Medsger TA Jr. Vasculitis in systemic sclerosis: Association with Sjogren's syndrome and the CREST syndrome variant. J Rheumatol 1987;14: 942-8.
37. Luse SA. Electron microscopic studies of brain tumors. Neurology 1960;10:881-905.
38. Luse SA, Zopf D, Cox JW. An electron microscopic study of in vitro and in vivo long-spacing collagen. Anat Rec 1963;145:254-8.
39. Matucci-Cerinic, Cinti S. Morroni M et al. Pachydermoperiostosis (primary hypertrophic osteoarthropathy): Report of a case with evidence endothelial and connective tissue involvement. Ann Rheum Dis 1989;48:240-6.
40. Tohgi H, Tabuchi M, Tomonaga M, Izumivama N. Spindle-shape, cross-banded structure in human peripheral nerves. Acta Neuropathol 1977;40:51-4.
41. Pillai PA. A banded structure in the connective tissue of nerve. J Ultrastruct Res 1964;11:455-68.
42. Richter RB. Peripheral neuropathy and connective tissue disease. J Neuropathol Exp Neurol 1954;13:168-80.