Hepatic adenocarcinoma expressing inhibin in a young patient on oral contraceptives

Virchows Archiv

Volumn 446, Issue 5, 2005, Pages 560-565

  Vrettou, Eleni ^a   Hytiroglou, Prodromos ^a   Sikas, Nikolaos ^b   Soultoyannis, Ioannis ^a   Goodman, Zachary D ^c  

^a ARISTOTLE UNIVERSITY MEDICAL SCHOOL   (Greece)

^b INTERBALKAN MEDICAL CENTER   (Greece)

^c ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

Author keywords

Adenocarcinoma; Cholangiocarcinoma; Inhibin; Liver

Indexed keywords

CA 19-9 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; CONTRAST MEDIUM; CYTOKERATIN 19; CYTOKERATIN 7; DESOGESTREL PLUS ETHINYLESTRADIOL; INHIBIN; ORAL CONTRACEPTIVE AGENT;

ADENOCARCINOMA; ADRENAL CORTEX TUMOR; ADULT; ANAMNESIS; ARTICLE; BILE DUCT CARCINOMA; CANCER GROWTH; CANCER LOCALIZATION; CASE REPORT; CELL DIFFERENTIATION; CELL HETEROGENEITY; CLINICAL FEATURE; FEMALE; GONAD TUMOR; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; LABORATORY TEST; LAPAROTOMY; LIVER CELL; LIVER CELL CARCINOMA; LIVER TUMOR; LOBECTOMY; MORPHOLOGY; OVARY TUMOR; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TROPHOBLASTIC TUMOR;

ABDOMINAL PAIN; ADENOCARCINOMA; ADULT; CA-19-9 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; CONTRACEPTIVES, ORAL, COMBINED; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INHIBINS; KERATIN-7; KERATINS; LIVER NEOPLASMS; MAGNETIC RESONANCE IMAGING; NAUSEA; TOMOGRAPHY, X-RAY COMPUTED; VOMITING;

EID: 21244455154     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-005-1241-3     Document Type: Article

References (13)

1. Altaee MY, Johnson PJ, Farrant JM, Williams R (1991) Etiologic and clinical characteristics of peripheral and hilar cholangiocarcinoma. Cancer 68:2051-2055
2. Anthony PP (2002) Tumours and tumour-like lesions of the liver and biliary tract: aetiology, epidemiology and pathology. In: MacSween RNM, Burt AD, Portmann BC, Ishak KG, Scheuer PJ, Anthony PP (eds) Pathology of the liver, 4th edn. Churchill Livingstone, London, pp 711-775
3. Azumi N, Czernobilsky B (2002) Immunohistochemistry. In: Kurman RJ (ed) Blaustein's pathology of the female genital tract, 5th edn. Springer, Berlin Heidelberg New York, pp 1251-1276
4. Ishak KG, Goodman ZD, Stocker JT (2001) Tumors of the liver and intrahepatic bile ducts. In: Atlas of tumor pathology, 3rd series, Fascicle 31. Armed Forces Institute of Pathology, Washington, pp 185-198
5. Kommoss F, Oliva E, Bhan AK, Young RH, Scully RE (1998) Inhibin expression in ovarian tumors and tumor-like lesions: an immunohistochemical study. Mod Path 11:656-664
6. Pelkey TJ, Frierson HF Jr, Mills SE, Stoler MH (1998) The alpha subunit of inhibin in adrenal cortical neoplasia. Mod Path 11:516-524
7. Shih IM, Kurman RJ (1999) Immunohistochemical localization of inhibin-alpha in the placenta and gestational trophoblastic lesions. Int J Gynecol Pathol 18:144-150
8. Yen S, Hsieh CC, MacMahon B (1987) Extrahepatic bile duct cancer and smoking, beverage consumption, past medical history, and oral contraceptive use. Cancer 59:2112-2116
9. Zhang PJ, Genega EM, Tomaszewski JE, Pasha TL, LiVolsi VA (2003) The role of calretinin, inhibin, melan-A, BCL-2, and C-kit in differentiating adrenal cortical and medullary tumors: an immunohistochemical study. Mod Path 16:591-597
10. Van Den Heuvel MC, Sloof MJH, Visser L, Muller M, De Jong KP, Poppema S, Gouw ASH (2001) Expression of anti-OV6 antibody and anti-N-CAM antibody along the biliary line of normal and diseased human livers. Hepatology 33:1387-1393
11. Renshaw AA, Granter SR (1998) A comparison of A103 and inhibin reactivity in adrenal cortical tumors: distinction from hepatocellular carcinoma and renal tumors. Mod Path 11:1160-1164
12. Iezzoni JC, Mills SE, Pelkey TJ, Stoler MH (1999) Inhibin is not an immunohistochemical marker for hepatocellular carcinoma. An example of the potential pitfall in diagnostic immunohistochemistry caused by endogenous biotin. Am J Clin Pathol 111:229-234
13. Lau SK, Prakash S, Geller SA, Alsabeh A (2002) Comparative immunohistochemical profile of hepatocellular carcinoma, cholangiocarcinoma, and metastatic adenocarcinoma. Hum Pathol 33:1175-1181