A subchronic toxicity study in rats and genotoxicity tests with an aqueous ethylcellulose dispersion

Food and Chemical Toxicology

Volumn 43, Issue 9, 2005, Pages 1355-1364

  DeMerlis, C C ^a   Schoneker, D R ^a   Borzelleca, J F ^b  

^a Colorcon ^*  (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Ethylcellulose; Ethylcellulose aqueous dispersion; Excipient; Excipient safety; Modified release coating; Polymeric dispersion; Surelease; Sustained release coating; Taste masking coating

Indexed keywords

ETHYL CELLULOSE; EXCIPIENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; BLOOD CHEMISTRY; BLOOD CLOTTING; BODY WEIGHT; BONE MARROW TOXICITY; CHROMOSOME DAMAGE; CONTROLLED STUDY; DRUG FORMULATION; DRUG SAFETY; FEMALE; FOOD INTAKE; GENOTOXICITY; HISTOPATHOLOGY; IN VIVO CULTURE; IN VIVO STUDY; MALE; METABOLIC ACTIVATION; MICRONUCLEUS TEST; MOTOR ACTIVITY; MOUSE; MUTAGENESIS; MUTAGENIC ACTIVITY; MUTATIONAL ANALYSIS; NEUROPATHOLOGY; NONHUMAN; ORGAN WEIGHT; RAT; TISSUE SECTION; TOXICITY TESTING; URINALYSIS;

ANIMALS; BEHAVIOR, ANIMAL; BLOOD COAGULATION; BODY WEIGHT; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; DIET; EATING; EXCIPIENTS; FEMALE; LYMPHOMA; MALE; MICE; MICRONUCLEUS TESTS; MUTAGENICITY TESTS; MUTAGENS; NERVOUS SYSTEM DISEASES; ORGAN SIZE; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; SALMONELLA TYPHIMURIUM;

ANIMALIA;

EID: 21244440195     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2005.03.008     Document Type: Article

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