Constituents of Zingiber aromaticum and their CYP3A4 and CYP2D6 inhibitory activity

Chemical and Pharmaceutical Bulletin

Volumn 53, Issue 3, 2005, Pages 333-335

  Subehan, ^a   Usia, Tepy ^a   Kadota, Shigetoshi ^a   Tezuka, Yasuhiro ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Cytochrome P450 2D6 (CYP2D6); Cytochrome P450 3A4 (CYP3A4); Drug herb interaction; Human liver microsome; Indonesian medicinal plant; Zingiber aromaticum

Indexed keywords

2,9 HUMULADIEN 6 OL 8 ONE; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; KETOCONAZOLE; METHANOL; PLANT EXTRACT; QUINIDINE; SESQUITERPENE; UNCLASSIFIED DRUG; ZINGIBER AROMATICUM EXTRACT;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG ISOLATION; DRUG METABOLISM; DRUG STRUCTURE; ENZYME INHIBITION; HERB DRUG INTERACTION; HUMAN; INDONESIA; LIVER MICROSOME; MEDICINAL PLANT; NONHUMAN; SPECTROSCOPY; ZINGIBER AROMATICUM; ZINGIBERACEAE;

CYTOCHROME P-450 CYP2D6; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INHIBITORS; METHANOL; MICROSOMES, LIVER; PLANTS, MEDICINAL; RHIZOME; SESQUITERPENES; SOLUTIONS; ZINGIBERACEAE;

EID: 21144456408     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.53.333     Document Type: Article

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