Interindividual variability in 5-fluorouracil metabolism and procainamide N-acetylation in human liver cytosol

Biological and Pharmaceutical Bulletin

Volumn 28, Issue 6, 2005, Pages 1071-1074

  Niwa, Toshiro ^a   Shiraga, Toshifumi ^a   Ohno, Yasuo ^b   Kagayama, Akira ^a  

^a ASTELLAS PHARMA INC   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

5 ffluorouracil; Dehydropyrimidine dehydrogenase; Human liver cytosol; N acetyltransferase 2; Procainamide

Indexed keywords

ACYLTRANSFERASE; ARYLAMINE ACETYLTRANSFERASE; DIHYDROPYRIMIDINE DEHYDROGENASE; FLUOROURACIL; PROCAINAMIDE; SULFADIMIDINE;

AGE; ARTICLE; CATALYSIS; DRUG ACETYLATION; DRUG CLEARANCE; DRUG HYDROLYSIS; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME KINETICS; GENDER; HUMAN; INTERINDIVIDUAL VARIATION; INTRASPECIFIC VARIATION; LIVER CYTOSOL; LIVER METABOLISM; LIVER MICROSOME;

ACETYLATION; ADOLESCENT; ADULT; AGED; CYTOSOL; FEMALE; FLUOROURACIL; HUMANS; LIVER; MALE; MIDDLE AGED; PROCAINAMIDE;

EID: 21144450065     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.28.1071     Document Type: Article

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