The management of elderly patients with T1-T2 breast cancer treated with or without radiotherapy

European Journal of Surgical Oncology

Volumn 31, Issue 5, 2005, Pages 473-478

  Livi, L ^a   Paiar, F ^a   Meldolesi, E ^a   Bianchi, S ^a   Cardona, G ^b   Cataliotti, L ^a   Crocetti, E ^c   Distante, V ^a   Simontacchi, G ^a   Scoccianti, S ^a   Talamonti, C ^a   Pallotta, S ^a   Biti, G P ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b CANCER RESEARCH AND PREVENTION INSTITUTE ISPO   (Italy)

^c Unita' Operativa Di Epidemiologia Clinica E Descrittiva   (Italy)

Author keywords

Breast cancer; Breast conserving surgery; Radiotherapy

Indexed keywords

ANTINEOPLASTIC AGENT; TAMOXIFEN;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; AXILLARY LYMPH NODE; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER GRADING; CANCER INCIDENCE; CANCER LOCALIZATION; CANCER RADIOTHERAPY; CANCER RELAPSE; CANCER RISK; CANCER STAGING; CLINICAL EXAMINATION; CONTROLLED STUDY; EVIDENCE BASED MEDICINE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; OUTCOMES RESEARCH; POSTOPERATIVE CARE; PRIORITY JOURNAL; RECURRENCE RISK; SEGMENTAL MASTECTOMY; STATISTICAL SIGNIFICANCE;

AGED; BREAST NEOPLASMS; CASE-CONTROL STUDIES; COMBINED MODALITY THERAPY; FEMALE; HUMANS; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RADIOTHERAPY, ADJUVANT; SURVIVAL ANALYSIS;

EID: 21144436650     PISSN: 07487983     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejso.2005.02.024     Document Type: Article

References (27)

1. U. Veronesi R. Saccozzi M. Del Vecchio A. Banfi C. Clemente M. De Lena et al. Comparing radical mastectomy with quadrantectomy, axillary dissection, and radiotherapy in patients with small cancers of the breast N Engl J Med 305 1981 6-11
2. B. Fischer C. Redmond R. Poisson R. Margolese N. Wolmark L. Wickerham et al. Eight-year results of a randomized clinical trial comparing total mastectomy and lumpectomy with or without irradiation in the treatment of breast cancer N Eng J Med 320 1989 822-828
3. G. Liljegren J. Holmberg A. Bergh A. Lindgren L. Tabar H.. Nordgren et al. Ten-year result after sector resection with or without postoperative radiotherapy for stage I breast cancer: A randomized trial J Clin Oncol 17 1999 2326-2333
4. U. Veronesi A. Luini M. Del Vecchio M. Greco V. Galimberti M. Merson et al. Radiotherapy after breast-preserving surgery in women with localized cancer of the breast N Engl J Med 328 1993 1587-1591
5. B. Fisher S. Anderson C.K. Redomod N. Wolmark D.L. Wickerham W.M. Cronin et al. Reanalysis and results after 12 years of follow-up in a randomized clinical trial comparing total mastectomy with lumpectomy with or without irradiaiton in the treatment of breast cancer N Engl J Med 333 1995 1456-1461
6. J.A. Van Dongen H. Bartelink I.S. Fentiman T. Lerut F. Mignolet G. Olthuis et al. Randomized clinical trial to assess the value of breast-conserving therapy for stage I and II breast cancer, EORTC 10801 trial In: National Institute of Health Consensus Development Conference on the treatment of early-stage breast cancer NCI monographs, No. 11 1992 Government Printing Office Washington, DC p. 15-18
7. N. Hebert-Croteau J. Brisson J. Latreille C. Blanchette L. Deschenes Compliance with consensus recommendations for the treatment of early stage breast carcinoma in elderly women Cancer 85 1999 1104-1113
8. T.E. Merchant B. McCormick J. Yahalom P. Borgen The influence of older age on breast cancer treatment decisions and outcome Int J Radiat Oncol Biol Phys 34 3 1996 565-570
9. B. Shank Ageism or Acumen - the treatment of older women with breast cancer Int J Radiat Oncol Biol Phys 34 3 1996 753-755
10. D.G. Richard A. Goldhirsch Radiotherapy to the conserved breast: Is it avoidable if the cancer is small? J Natl Cancer Inst 86 9 1994
11. A. Herd-Smith A. Russo M.G. Muraca M.R. Del Turco G. Cardona Prognostic factors for lymphedema after primary treatment of breast carcinoma Cancer 92 2001 1783-1787
12. R. Zucali M. Merson M. Placucci S. Di Palma U. Veronesi Soft-tissue sarcoma of the breast after conservative surgery and irradiation for early breast mammary cancer Radiother Oncol 30 1994 271-273
13. W.F. Athas M. Adams-Cameron W.C. Hunt A. Amir-Fazli C.R. Key Travel distance to radiation therapy and receipt of radiotherapy following breast-conserving surgery J Natl Cancer Inst 92 2000 269-271
14. B.L. Fowble Long-term results of conservative surgery and radiation for early stage breast cancer: What have we wrought? Int J Radiat Oncol Biol Phys 33 2 1995 535-537
15. K. Holli R. Saarisko J. Isola H. Joensuu M. Hakama Lumpectomy whit or without postoperative radiotherapy for breast cancer with favourable prognostic features: Results of a randomized study Br J Cancer 84 2 2001 164-169
16. P. Malmstrom L. Holmberg H. Anderson J. Mattsson P.E. Jonsson L. Tennvall-Nittby et al. Breast conservation surgery, with or without radiotherapy in women with lympho node negative breast cancer: A randomised clinical trial in a population with access to public mammography screening Eur J Cancer 39 12 2003 1690-1697
17. S.J. Schnitt Can we identify patients with invasive breast cancer adequately treated width breast-conserving surgery alone? Mod Pathol 11 2 1998 129-133
18. R. Kim N. Nishimoto A. Osaki J. Kojima S. Fujii K. Inai et al. An analysis of relapsed breast cancer in patients previously treated with breast conserving surgery Breast Cancer 8 2 2001 146-152
19. G. Liljegren L. Holmberg H.-O. Adami G. Westman S. Graffman J. Bergh et al. Sector resection with or without postoperative radiotherapy for stage I breast cancer: Five-year results of a randomized trial J Natl Cancer Inst 86 9 1994 717-722
20. U. Veronesi B. Salvadori A. Luini A. Banfi R. Zucali M. Del Vecchio et al. Conservative treatment of early breast cancer. Long-term result of 1232 cases treated with quadrantectomy, axillary dissection, and radiotherapy Ann Surg 211 3 1990 250-259
21. U. Veronesi E. Marubini L. Mariani V. Galimberti A. Luini P. Veronesi et al. Radiotherapy after breast conserving surgery in small breast carcinoma: Long-term results of a randomized trial Ann Oncol 12 2001 997-1003
22. The Uppsala-Orebro Breast cancer Study Group Sector resection with or without postoperative radiotherapy for stage I breast cancer: A randomized trial J Natl cancer Inst 82 1990 277-282
23. B. Fischer Lumpectomy versus quadrantectomy for breast conservation: A critical appraisal Eur J Cancer 31A 10 1995 1567-1569
24. K.I. Blank C.E. Scott-Conner H. Menck D.P. Winchester Axillary dissection in breast-conserving surgery for stage I and II breast cancer: A National Cancer Data Base study of patterns of omission and implications for survival J Am Coll Surg 188 6 1999 586-595
25. L.J. Solin D.J. Schultz B.L. Fowble Ten-year results of the treatment of early-stage breast carcinoma in elderly women using breast-conserving surgery and definitive breast irradiation Int J Radiat Oncol Biol Phys 33 1 1995 45-51
26. T. Gruenberg M. Gorlitzer T. Soliman M. Rudas M. Mittlboeck M. Gnant et al. It is possible to omit postoperative irradiation in a highly selected group of elderly breast cancer patients Breast Cancer Res Treat 50 1 1998 37-46
27. G. Liljegren A. Lindgren J. Bergh Risk factors for local recurrence after conservative treatment in stage I breast cancer. Definition of a subgroup not requiring radiotherapy Ann Oncol 8 1997 235-241