Reduction of conjunctival bacterial flora by povidone-iodine, ofloxacin and chlorhexidine in an outpatient setting

Acta Ophthalmologica Scandinavica

Volumn 83, Issue 3, 2005, Pages 360-363

  Barkana, Yaniv ^a   Almer, Zina ^a   Segal, Ori ^a   Lazarovitch, Zipora ^a   Avni, Issac ^a   Zadok, David ^a  

^a ASSAF HAROFEH MEDICAL CENTER   (Israel)

Author keywords

Chlorhexidine; Endophthalmitis; Ofloxacin; Povidone iodine; Prophylaxis; Suture

Indexed keywords

CHEX; CHLORHEXIDINE; OFLOX; OFLOXACIN; POVIDONE IODINE;

ANTISEPSIS; ARTICLE; BACTERIAL COUNT; BACTERIAL FLORA; BACTERIUM COLONY; BACTERIUM CULTURE; COLONY FORMING UNIT; COMMENSALISM; CONJUNCTIVITIS; CONTROLLED STUDY; DISINFECTION; ENDOPHTHALMITIS; HUMAN; INCUBATION TEMPERATURE; INCUBATION TIME; KRUSKAL WALLIS TEST; MAJOR CLINICAL STUDY; NONHUMAN; OUTPATIENT DEPARTMENT; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; SUTURE REMOVAL; VISUAL SYSTEM EXAMINATION; WILCOXON SIGNED RANKS TEST;

ANTI-INFECTIVE AGENTS, LOCAL; ANTIBIOTIC PROPHYLAXIS; BACTERIA; CHLORHEXIDINE; COLONY COUNT, MICROBIAL; CONJUNCTIVA; ENDOPHTHALMITIS; EYE INFECTIONS, BACTERIAL; HUMANS; OFLOXACIN; OPHTHALMIC SOLUTIONS; OUTPATIENTS; POVIDONE-IODINE;

EID: 21044457866     PISSN: 13953907     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0420.2005.00414.x     Document Type: Article

References (30)

1. Akkan AG, Mutlu I, Ozyazgan S et al. (1997a): Comparative tear concentrations of topically applied ciprofloxacin, ofloxacin and norfloxacin in human eyes. Int J Clin Pharmacol Ther 35: 214-217.
2. Akkan AG, Mutlu I, Ozyazgan S et al. (1997b): Penetration of topically applied ciprofloxacin, norfloxacin and ofloxacin into the aqueous humour of the uninflamed human eye. J Chemother 9: 257-262.
3. Apt L, Isenberg SJ, Yoshimori R et al. (1985): The effect of povidone-iodine solution applied at the conclusion of ophthalmic surgery. Am J Ophthalmol 119: 701-705.
4. Apt L, Isenberg S, Yoshimori R & Paez JH (1984): Chemical preparation of the eye in ophthalmic surgery. III. Effect of povidone-iodine on the conjunctiva. Arch Ophthalmol 102: 728-729.
5. Apt L, Isenberg SJ, Yoshimori R & Spierer A (1989): Outpatient topical use of povidone-iodine in preparing the eye for surgery. Ophthalmology 96: 289-292.
6. Bannerman TL, Rhoden DL, McAllister SK et al. (1997): The source of coagulase-negative staphylococci in the Endophthalmitis Vitrectomy Study. A comparison of eyelid and intraocular isolates using pulsed-field gel electrophoresis. Arch Ophthalmol 115: 357-361.
7. Boes DA, Lindquist TD, Fritsche TR & Kalina RE (1992): Effects of povidone-iodine chemical preparation and saline irrigation on the perilimbal flora. Ophthalmology 99: 1569-1574.
8. Bower KS, Kowalski RP & Gordon YJ (1996): Fluoroquinolones in the treatment of bacterial keratitis. Am J Ophthalmol 121: 712-715.
9. Cantor LB, Donnenfeld E, Katz LJ et al. (2001): Penetration of ofloxacin and ciprofloxacin into the aqueous humour of eyes with functioning filtering blebs: a randomized trial. Arch Ophthalmol 119: 1254-1257.
10. Cekic O, Batman C, Totan Y et al. (1999): Penetration of ofloxacin and ciprofloxacin in aqueous humour after topical administration. Ophthalmic Surg Lasers 30: 465-468.
11. Ciulla TA, Starr MB & Masket S (2002): Bacterial endophthalmitis prophylaxis for cataract surgery: an evidence-based update. Ophthalmology 109: 13-24.
12. Connel JF & Rousselot LM (1964): Povidone-iodine: extensive surgical evaluation of a new antiseptic agent. Am J Surg 108: 849-855.
13. Culbert RB & Devenyi RG (1999): Bacterial endophthalmitis after suture removal. J Cataract Refract Surg 25: 725-727.
14. Das T, Sharma S & Singh J (2001): Evaluation of glutaraldehyde and povidone-iodine for sterilization of wide-field contact vitrectomy lenses. Ophthalmic Surg Lasers 32: 300-304.
15. Illingworth CD & Cook SD (1998): Acanthamoeba keratitis. Surv Ophthalmol 42: 493-508.
16. Kosrirukvongs P, Wanachiwanawin D & Visvesvara GS (1999): Treatment of acanthamoeba keratitis with chlorhexidine. Ophthalmology 106: 798-802.
17. Mindrup EA, Dubbel PA & Doughman DJ (1993): Betadine decontamination of donor globes. Cornea 12: 324-329.
18. Montan PG, Setterquist H, Marcusson E et al. (2000): Preoperative gentamicin eye drops and chlorhexidine solution in cataract surgery. Experimental and clinical results. Eur J Ophthalmol 10: 286-292.
19. Montan PG, Wejde G, Koranyi G & Rylander M (2002): Prophylactic intracameral cefuroxime. Efficacy in preventing endophthalmitis after cataract surgery. J Cataract Refract Surg 28: 977-981.
20. Neu HC (1991): Microbiologic aspects of fluoroquinolones. Am J Ophthalmol 112: 15S-24S.
21. Phinney RB, Mondino BJ, Hofbauer JD et al. (1988): Corneal oedema related to accidental Hibiclens exposure. Am J Ophthalmol 106: 210-215.
22. Pierard GE, Pierard-Franchimont C & Arrese JE (1997): Povidone-iodine wash solutions in the prevention of superficial fungal infections; predictive evaluation using the corneofungimetry bioassay. Eur J Clin Pharmacol 53: 101-104.
23. Prajna NV, George C, Selvaraj S et al. (2001): Bacteriologic and clinical efficacy of ofloxacin 0.3% versus ciprofloxacin 0.3% ophthalmic solutions in the treatment of patients with culture-positive bacterial keratitis. Cornea 20: 175-8.
24. Snyder-Perlmutter LS, Katz HR & Melia M (2000): Effect of topical ciprofloxacin 0.3% and ofloxacin 0.3% on the reduction of bacterial flora on the human conjunctiva. J Cataract Refract Surg 26: 1620-1625.
25. Speaker MG, Milch FA, Shah MK et al. (1991): Role of external bacterial flora in the pathogenesis of acute postoperative endophthalmitis. Ophthalmology 98: 639-649.
26. Spigelman AV, Doughman DJ, Lindstrom RL & Nelson JD (1988): Visual loss following suture removal postkeratoplasty. Cornea 7: 214-217.
27. Tabor E, Bostwick DC & Evans CC (1989): Corneal damage due to eye contact with chlorhexidine gluconate. JAMA 261: 557-558.
28. Varley GA, Meisler DM, Benes SC et al. (1990): Hibiclens keratopathy. A clinico-pathologic case report. Cornea 9: 341-346.
29. Weiss JL, Nelson JD, Lindstrom RL & Doughman DJ (1985): Bacterial endophthalmitis following penetrating keratoplasty suture removal. Cornea 3: 278-280.
30. Wille H (1982): Assessment of possible toxic effects of polyvinylpyrrolidone-iodine upon the human eye in conjunction with cataract extraction. An endothelial specular microscope study. Acta Ophthalmol (Copenh) 60: 955-960.