Proteasomal degradation of Kir6.2 channel protein and its inhibition by a Na+ channel blocker aprindine

Biochemical and Biophysical Research Communications

Volumn 331, Issue 4, 2005, Pages 1001-1006

  Tanaka, Hiroaki ^a   Miake, Junichiro ^b   Notsu, Tomomi ^b   Sonyama, Kazuhiko ^a   Sasaki, Norihito ^b   Iitsuka, Kazuhiko ^a   Kato, Masaru ^a   Taniguchi, Shin Ichi ^a   Igawa, Osamu ^a   Yoshida, Akio ^a   Shigemasa, Chiaki ^a   Hoshikawa, Yoshiko ^b   Kurata, Yasutaka ^c   Kuniyasu, Akihiko ^d   Nakayama, Hitoshi ^d   Inagaki, Nobuo ^e   Nanba, Eiji ^f   Shiota, Goshi ^f   Morisaki, Takayuki ^g   Ninomiya, Haruaki ^a   Kitakaze, Masafumi ^g   Hisatome, Ichiro ^b   more..

^a TOTTORI UNIVERSITY   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

^c KANAZAWA MEDICAL UNIVERSITY   (Japan)

^d KUMAMOTO UNIVERSITY   (Japan)

^e AKITA UNIVERSITY   (Japan)

^f TOTTORI UNIVERSITY   (Japan)

^g NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Aprindine; Kir6.2; Proteasome

Indexed keywords

APRINDINE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CHLOROQUINE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; LACTACYSTIN; MEMBRANE PROTEIN; NICORANDIL; PROTEASOME INHIBITOR; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ENDOPLASMIC RETICULUM; FOREBRAIN; GOLGI COMPLEX; HEART MUSCLE CELL; IN VITRO STUDY; MONKEY; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; UBIQUITINATION;

ANIMALS; APRINDINE; CELLS, CULTURED; ENDOPLASMIC RETICULUM; GOLGI APPARATUS; HYDROLYSIS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; SODIUM CHANNEL BLOCKERS; UBIQUITIN;

EID: 21044456875     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.04.011     Document Type: Article

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