Patient and physician attitudes toward breast cancer clinical trials: Developing interventions based on understanding barriers

Clinical Breast Cancer

Volumn 6, Issue 1, 2005, Pages 45-54

  Melisko, Michelle E ^a   Hassin, Fern ^a   Metzroth, Lauren ^a   Moore, Dan H ^a   Brown, Beth ^a   Patel, Kiran ^b   Rugo, Hope S ^a   Tripathy, Debu ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Telik Inc   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Participation; Patient education; Randomization

Indexed keywords

ADULT; AGE DISTRIBUTION; ALTERNATIVE MEDICINE; ARTICLE; AWARENESS; BREAST CANCER; CANCER PATIENT; CANCER RECURRENCE; CANCER STAGING; CLINICAL PRACTICE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; COST BENEFIT ANALYSIS; DEMOGRAPHY; EXPERIMENTAL DESIGN; FEMALE; GEOGRAPHIC DISTRIBUTION; HEALTH CARE PLANNING; HEALTH PROGRAM; HEALTH SURVEY; HUMAN; MAJOR CLINICAL STUDY; MEDICAL SPECIALIST; MEDICAL STAFF; PATIENT ATTITUDE; PHYSICIAN ATTITUDE; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SUPPORT GROUP; TIME;

EID: 21044440296     PISSN: 15268209     EISSN: None     Source Type: Journal    
DOI: 10.3816/CBC.2005.n.008     Document Type: Article

References (22)

1. Friedman MA, Cain MF. National Cancer Institute sponsored cooperative clinical trials. Cancer 1990; 65(10 suppl):2376-2382.
2. Simon MS, Brown DR, Du W, et al. Accrual to breast cancer clinical trials at a university-affiliated hospital in metropolitan Detroit. Am J Clin Oncol 1999; 22:42-46.
3. Gotay CC. Accrual to cancer clinical trials: directions from the research literature. Soc Sci Med 1991; 33:569-577.
4. Kemeny MM, Peterson BL, Kornblith AB, et al. Barriers to clinical trial participation by older women with breast cancer. J Clin Oncol 2003; 21:2268-2275.
5. Lacher MJ. Patients and physicians as obstacles to a randomized trial. Semin Oncol 1981; 8:424-429.
6. Lara PN Jr, Higdon R, Lim N, et al. Prospective evaluation of cancer clinical trial accrual patterns: identifying potential barriers to enrollment. J Clin Oncol 2001; 19:1728-1733.
7. Cassileth BR, Lusk EJ, Miller DS, et al. Attitudes toward clinical trials among patients and the public. JAMA 1982; 248:968-708.
8. Taylor KM, Margolese RG, Soskolne CL. Physicians' reasons for not entering eligible patients in a randomized clinical trial of surgery for breast cancer. N Engl J Med 1984; 310:1363-1367.
9. Long DG. Clinical trials. A family physician's perspective. Cancer 1991; 67(6 suppl):1798-1799.
10. Farrar WB. Clinical trials. Access and reimbursement. Cancer 1991; 67(6 suppl):1779-1782.
11. Winn RJ, Kerner JF, et al. An evaluation of physician determinants in referral of patients for cancer clinical trials in the community setting. In: Engstrom PF, Mortenson LE, Anderson PN, eds. Advances in Cancer Control: Epidemiology and Research. New York: John Wiley & Sons; 1985.
12. Benson AB III, Pregler JP, Bean JA, et al. Oncologists' reluctance to accrue patients onto clinical trials: an Illinois Cancer Center study. J Clin Oncol 1991; 9:2067-2075.
13. Siminoff LA, Zhang A, Colabianchi N, et al. Factors that predict the referral of breast cancer patients onto clinical trials by their surgeons and medical oncologists. J Clin Oncol 2000; 18:1203-1211.
14. Millon-Underwood S, Sanders E, M. Davis. Determinants of participation in state-of-the-art cancer prevention, early detection/screening, and treatment trials among African-Americans. Cancer Nurs 1993; 16:25-33.
15. Advani AS, Atkeson B, Brown CL, et al. Barriers to the participation of African-American patients with cancer in clinical trials: a pilot study. Cancer 2003; 97:1499-1506.
16. Fleissig A, Jenkins V, Fallowfield L. Results of an intervention study to improve communication about randomised clinical trials of cancer therapy. Eur J Cancer 2001; 37:322-331.
17. Ellis PM, Butow PN, Tattersall MH, et al. Randomized clinical trials in oncology: understanding and attitudes predict willingness to participate. J Clin Oncol 2001; 19:3554-3561.
18. Fallowfield L, Ratcliffe D, Souhami R. Clinicians' attitudes to clinical trials of cancer therapy. Eur J Cancer 1997; 33:2221-2229.
19. Richardson MA, Post-White J, Singletary SE, et al. Recruitment for complementary/alternative medicine trials: who participates after breast cancer. Ann Behav Med 1998; 20:190-198.
20. Hyodo I, Eguchi K, Nishina T, et al. Perceptions and attitudes of clinical oncologists on complementary and alternative medicine: a nationwide survey in Japan. Cancer 2003; 97:2861-2868.
21. Ellis PM, Butow PN, Tattersall MH. Informing breast cancer patients about clinical trials: a randomized clinical trial of an educational booklet. Ann Oncol 2002; 13:1414-1423.
22. Paskett ED, Cooper MR, Stark N, et al. Clinical trial enrollment of rural patients with cancer. Cancer Pract 2002; 10:28-35.