Apoptosis-resistant phenotype of classical Hodgkin's lymphoma is not mediated by somatic mutations within genes encoding members of the death-inducing signaling complex (DISC) [3]

Leukemia

Volumn 19, Issue 6, 2005, Pages 1079-1082

  Thomas, R K ^a,b,e   Schmitz, R ^c   Harttrampf, A C ^a   Abdil Hadi, A ^a   Wickenhauser, C ^a   Distler, V ^c,d   Hansmann, M L ^d   Schultze, J L ^a,b   Kuppers R ^c   Wolf, Juerge ^a,b  

^a UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

^c UNIVERSITY OF ESSEN MEDICAL SCHOOL   (Germany)

^d GOETHE UNIVERSITY   (Germany)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 10; CASPASE 8; DEATH RECEPTOR; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN;

ALLELE; APOPTOSIS; CANCER CLASSIFICATION; CANCER RISK; EXON; GENE AMPLIFICATION; GENE FREQUENCY; GENE MUTATION; GENE SEQUENCE; GENETIC CODE; HODGKIN DISEASE; HUMAN; LETTER; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION; GENETICS; MUTATION; PATHOLOGY; SIGNAL TRANSDUCTION;

APOPTOSIS; HODGKIN DISEASE; HUMANS; MUTATION; PHENOTYPE; SIGNAL TRANSDUCTION;

EID: 20844463227     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2403747     Document Type: Letter

References (8)

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4. Müschen M, Re D, Bräuninger A, Wolf J, Hansmann ML, Diehl V et al. Somatic mutations of the CD95 gene in Hodgkin and Reed-Sternberg cells. Cancer Res 2000; 60: 5640-5643.
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7. Thomas RK, Kallenborn A, Wickenhauser C, Schultze JL, Draube A, Vockerodt M et al. Constitutive expression of c-FLIP in Hodgkin and Reed-Sternberg cells. Am J Pathol 2002; 160: 1521-1528.
8. Dutton A, O'Neil JD, Milner AE, Reynolds GM, Starczynski J, Crocker J et al. Expression of the cellular FLICE-inhibitory protein (c-FLIP) protects Hodgkin's lymphoma cells from autonomous Fas-mediated death. Proc Natl Acad Sci USA 2004; 101: 6611-6616.