Helicobacter pylori infection in pediatric population: Epidemiology, pathophysiology, and therapy

Fetal and Pediatric Pathology

Volumn 23, Issue 1, 2004, Pages 11-28

  Wallis Crespo, M Carolina ^a   Crespo, Antonio ^b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b Florida Infectious Diseases Group   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; ANTIBIOTIC AGENT; CAGA PROTEIN; CLARITHROMYCIN; IMIDAZOLE; INACTIVATED VACCINE; MACROLIDE; OMEPRAZOLE; PENICILLIN G; BACTERIAL VACCINE;

ABDOMINAL PAIN; ANTIBIOTIC RESISTANCE; BACTERIAL GENOME; BACTERIAL TRANSMISSION; BACTERIUM CULTURE; CHILD; CHRONIC GASTRITIS; CLINICAL TRIAL; DIARRHEA; DRUG EFFICACY; DUODENUM ULCER; ENZYME ASSAY; FECES ANALYSIS; GASTROINTESTINAL ENDOSCOPY; GENE SEQUENCE; GRAM NEGATIVE BACTERIUM; HELICOBACTER HEILMANNII; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; IRON DEFICIENCY ANEMIA; NAUSEA; NONHUMAN; PATHOPHYSIOLOGY; PEPTIC ULCER; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; REVIEW; SEROLOGY; SIDE EFFECT; STOMACH ADENOCARCINOMA; STOMACH BIOPSY; STOMACH CANCER; STOMACH LYMPHOMA; UREA BREATH TEST; URTICARIA; VOMITING; ANTIBIOTIC THERAPY; ANTIGEN DETECTION; BACTERIAL COLONIZATION; CLINICAL FEATURE; CONFERENCE PAPER; DEVELOPING COUNTRY; DIAGNOSTIC PROCEDURE; ENZYME ACTIVITY; GASTRITIS; HISTOPATHOLOGY; MICROBIOLOGICAL EXAMINATION; PEDIATRICS; STOMACH ANTRUM;

ANTI-BACTERIAL AGENTS; BACTERIAL VACCINES; CHILD; GASTROINTESTINAL DISEASES; GENOME, BACTERIAL; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS;

EID: 20844461848     PISSN: 15227952     EISSN: None     Source Type: Journal    
DOI: 10.1080/15227950490494856     Document Type: Review

References (82)

1. Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1984; Jun 16:1 (8390):1311-1315.
2. Crespo A, Suh B. Helicobacter pylori infection: Epidemiology, pathophysiology and therapy. Arch Pharm Res 2001;24 (6):485-498.
3. Borody TJ, George L, Brandl S, Andrews P, Ostapowicz N, Hyland L, Devine M. Helicobacter pylori- negative duodenal ulcer. Am J Gastroenterol 1991;86:1154-1157.
4. Morgner A, Bayerdorffer E, Meining A, Stolte M, Kroher G. Helicobacter heilmnanii and gastric cancer. Lancet 1995;346:511-512.
5. Stolte M, Kroher G, Meining A, Morgner A, Bayerdoffer E, Bethke B. A comparison of Helicobacter pylori and Helicobacter heilmnanii gastritis. A matched control study involving 404 patients. Scand J Gastroenterol 1997;32:28-33.
6. Tomb JF, White O, Kerlavage AR, et al. The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature 1997;388 (6642):539-547.
7. Burnens AP, Stanley J, Schaad UB, Nicolet J. Novel Campylobacter-like organism resembling Helicobacter fennelliae isolated from a boy with gastroenteritis and from dogs. J Clin Microbiol 1993;31:1916-1917.
8. Stanley J, Linton D, Burnens AP, Dewhirst FE, Owen RJ, Porter A, On SL, Costas M. Helicobacter canis sp. Nov. a new species from dogs: An integrated study of phenotype and genotype. J Gen Microbiol 1993;139:2495-2504.
9. Fox JG, Dewhirts FE, Shen ZL, Feng Y, Taylord NS, Paster BJ, Ericson, R, Lau CN, Correa P, Araya JC, Roa I. Hepatic Helicobacter species identified in bile and gallbladder tissue from Chileans with chronic cholecystitis. Gastroenterology 1998;114:1016-1017.
10. Skirrow MB. Taxonomy, biotyping, isolation and detection: Report on the session. In Pearson DA, Skirrow MB, Rowe B, et al., eds. Campylobacter II. London: Public Health Laboratory Service, 1983:33-38.
11. Marshall BJ, Warren JR, Francis GJ, Langton SR, Goodwin CS, Blincow ED. Rapid urease test in the management of Campylobacter pyloridis- associated gastritis. Am J Gastroenterol 1987;82:200-210.
12. Hazell SL, Lee A, Brady L, Hennessy W. Campylobacter pyloridis and gastritis: Association with intercellular spaces and adaptation to an environment of mucus as important factors in colonization of the gastric epithelium. J Infect Dis 1986;153:658-663.
13. Krajden S, Bohnen J, Anderson J, Kempston J, Fuksa M, Matlow A, Marcon N, Haber G, Kortan P, Karmali M, Corey P, Petrea C, Babida C, Hayman S. Comparison of selective and non selective media for recobery of Campylobacter pylori from antral biopsies. J Clin Microbiol 1987;25:1117-1118.
14. Parsonnet J, Welch K, Compton C, Strauss R, Wang T, Kelsey P, Ferraro MJ. Simple microbiologic detection of Campylobacter pylori. J Clin Microbiol 1988;26:948-949.
15. Ansorg R, Von Recklinghausen G, Pomarius R, Schmid EN. Evaluation of techniques for isolation, subcultivation and preservation of Helicobacter pylori. J Clin Microbiol 1991;29:51-53.
16. Eaton KA, Brooks CL, Morgan DR, Krakowka S. Essential role of urease in pathogenesis of gastritis induced by Helicobacter pylori in gnotobiotic piglets. Infect Immun 1991;59:2470-2475.
17. Foxall PA, Hu L, Mobley HL. Use of polymerase chain reaction-amplified Helicobacter pylori urease structural genes for differentiation of isolates. J Clin Microbiol 1992;(30):739-741.
18. Blaser MJ, Berg D. Helicobacter pylori genetic diversity. J Clin Invest 2001;107(7):767-773.
19. Blaser M, Atherton J. Helicobacter pylori persistence. J Clin Invest 2004;113(3):321-333.
20. Wewer V, Kalach N. Helicobacter pylori infection in pediatrics review. Helicobacter 2003;8 suppl 1:61-67.
21. Dooley CP, Cohen H, Fitzgibbons PL, Bauer M, Appleman MD, Perez-Perez GI, Blaser MJ. Prevalence of Helicobacter pylori infection and histologic gastritis in asymptomatic persons. N Engl J Med 1989;321:1562-1566.
22. Bardhan, P. Epidemiological features of Helicobacter pylori infection in developing countries. Clin Infect Dis 1997;25:973-978.
23. Sathar MA, Gouws E, Simjee AE, Mayat AM. Seroepidemiological study of Helicobacter pylori infection in South African children. Trans Roy Soc Trop Med Hyg 1997;91:393-395.
24. Graham DY, Malaty HM, Evans DG, Evans DJ Jr, Klein PD, Adam E. Epidemiology of Helicobacter pylori in an asymptomatic population in the United States. Effect of age, race, and socioeconomic status. Gastroenterology 1991;100:1495-1501.
25. Everhart JE. Recent developments in the epidemiology of Helicobacter pylori. Gastroenterol Clin North Am 2000;29:559-578.
26. Robinson LG, Black FL, Lee FK, et al. Helicobacter pylori prevalence among indigenous peoples of South America. J Infect Dis 2002;186:1131-1137.
27. Glynn MK, Friedman CR, Gold BD, et. al. Seroincidence of Helicobacter pylori infection in a cohort of rural Bolivian children: Acquisition and analysis of possible risk factors. Clin Infect Dis 2002;35:1059-1065.
28. Rothenbacher D, Bode G, Brenner H. Dynamics of Helicobacter pylori infection in early childhood in a high risk group living in Germany: Loss of infection higher than acquisition. Aliment Pharmacol Ther 2002;16:1663-1668.
29. Seo JK, Ko JS, Choi KD. Serum ferritin and Helicobacter pylori infection in children: a seroepidemilogic study in Korea. J Gastroenterol Hepatol 2002;17:754-757.
30. Rothenbacher D, Bode G, Brenner H. History of breastfeeding and Helicobacter pylori infection in preschool children: Result of a population-based study from Germany. Int J Epidemiol 2002;31:632-637.
31. Rothenbacher D, Winkler M, Gonser T, Adler G, Brenner H. Role of infected parents in transmission of Helicobacter pylori to their children. Pediatr Infect Dis J 2002;21:674-679.
32. Matsuda R, Morizane T, Tsunematsu S, Kawana I, Tomiyama M. Helicobacter pylori prevalence in dentists in Japan: a seroepidemiological study. J Gastroenterol 2002;37(4):255-259.
33. De Giacomo C, Valdambrini V, Lizzoli F, Gissi A, Palestra, M, Tinelli C, Zagan M, Bazzoli F. A population-based survey on gastrointestinal tract symptoms and Helicobacter pylori infection in children and adolescents. Helicobacter 2002;7:356.
34. Gold B, Coletti R, Abbott M, et al. Evidence-based guidelines for an approach to the diagnosis and treatment of Helicobacter pylori infection in children: Recommendation for diagnosis and treatment. J Pediatr Gastroenterol Nutr 2000;31:490-497.
35. Ozgenc F, Akman SA, Arikan C, Alkanat MB, Aydogdu Y. Treatment of Helicobacter pylori gastritis improves dyspeptic symptoms in Turkish children. J Pediatr Gastroenterol Nutr 2003;36:507.
36. Gottrand F. Helicobacter pylori infection: What are the specific questions in childhood? Gastroenterol Clin Biol 2003;27:484-487.
37. Takahashi M, Kimura H, Watanabe K. Helicobacter pylori infection in patients with idiopathic short stature. Pediatr Int 2002;44:277-280.
38. Özcay F, Demir H, Özen H, et al. Normal growth in young children with Helicobacter pylori infection. J Pediatr Gastroenterol Nutr 2002;35:102.
39. Sykora J, Varvarovska K, Kuntscherova J, et al. Symptomatology and specific characteristics of chronic gastritis caused by Helicobacter pylori infection in children in the Czech population-epidemiologic, clinical, endoscopic and histomorphologic study. Cas Lek Cesk 2002;141:615-621.
40. Kostaki M, Fessatou S, Karpathios T. Refractory iron-defiency anaemia due to silent Helicobacter pylori gastritis in children. Eur J Peditr 2003;162:177-179.
41. Parsonnet J, Friedman GD, Vandersteen DP, Chang Y, Vogelman JH, Orentriech N, Sibley RK. Helicobacter pylori infection and the risk of gastric carcinoma. N Engl J Med 1991;325:1127-1131.
42. Graham DY, Lew GM, Klein PD, Evans DJ Jr, Saeed ZA, Malaty HM. Effect of treatment of Helicobacter pylori infection on the long-term recurrence of gastric or duodenal ulcer. A randomized, controlled study. Ann Intern Med 1992;116:705-708.
43. Hopkins RJ, Girardi L, Turney EA. Relationship between Helicobacter pylori eradication and reduced duodenal and gastric ulcer recurrence: A review. Gastroenterology 1996;110:1244-1252.
44. Bontems P, Robert F, Van Gossum A, Cadranel S, Marcart F. Helicobacter pylori modulation of gastric and duodenal mucosal T cell cytokine secretions in children compared with adults. Helicobacter 2003;8(3):216-226.
45. Tsang KW, Lam SK. Extragastroduodenal conditions associated with Helicobacter pylori infection. Hong Kong Med J 1999;5:169-174.
46. Parsonnet J. Helicobacter pylori. Infect Dis Clin North Am 1998;12:185-197.
47. El-Zimaity HM, Al-Assi MT, Genta RM, Graham DY. Confirmation of successful therapy of Helicobacter pylori infection: Number and site of biopsies or a rapid urease test. Am J Gastroenterol 1995;90:1962-1964.
48. Andrew A, Wyatt JI, Dixon MF. Observer variation in the assessment of chronic gastritis according to the Sydney system. Histopathology 1994;25:317-322.
49. Cutler AF. Testing for Helicobacter pylori in clinical practice. Am J Med 1996;100:35S-39S.
50. Elitzur Y, Lawrence Z, Triest WE. Distribution of Helicobacter pylori organisms in the stomachs of children with H. pylori infection. Hum Pathol 2002;33:1133-1135.
51. Bahu MGS, da Silveira TR, Maguilnick I, Ulbrich-Kulezynski J. Endoscopic nodular gastritis. An endoscopic indicator of high-grade bacterial colonization and severe gastritis in children with Helicobacter pylori. J Pediatr Gastroenterol Nutr 2003;36:217-222.
52. Cutler AF, Havstad S, Ma CK, Blaser MJ, Perez-Perez GI, Schubert TT. Accuracy of invasive and noninvasive tests to diagnose Helicobacter pylori infection. Gastroenterology 1995;109:136-141.
53. Cohen H. Peptic ulcer and Helicobacter pylori. Gastroenterol Clin North Am 2000;29:775-789.
54. Kuipers EJ, Uyterlinde AM, Pena AS, Hazenberg HJ, Bloemena E, Linderman J, Klinkenberg-Knol EC, Meuwissen SG. Increase of Helicobacter pylori associated corpus gastritis during acid suppressive therapy: Indications for long-term safety. Am J Gastroenterol 1995;90:1401-1406.
55. Brown KE, Peura DA. Diagnosis of Helicobacter pylori infection. Gastroenterol Clin North Am 1993;22:105-115.
56. Marshall BJ, Goodwin CS. Revised nomenclature of Campylobacter pyloridis. Int J Syst Bacteriol 1987;37:68.
57. Ho GY, Windsor HM. Accurate diagnosis of Helicobacter pylori. Polymerase chain reaction test. Gastroenterol Clin North Am 2000;29:903-915.
58. VanZwet AA, Thijs JC, Kooistra-Smid AM, Schirm J, Snijder JA. Sensitivity of culture compared with that of polymerase chain reaction for detection of Helicobacter pylori from antral biopsy samples. J Clin Microbiol 1993;31:1918-1920.
59. Roosendaal R, Kuipers EJ, Van den Brule AJ, Pena AS, Uyterlinde AM, Walboomers JM, Meuwissen SG, de Graff J. Importance of the fiberoptic endoscope cleaning procedure for detection of Helicobacter pylori in gastric biopsy specimens by PCR. J Clin Microbiol 1994;32:1123-1126.
60. Oleastro M, Matos R, Cabral J, et al. Evaluation of a Western-Blot test, Helico Blot 2.1, in the diagnosis of Helicobacter pylori infection in a pediatric population. Helicobacter 2002;7:210-215.
61. Day AS, Sherman PM. Accuracy of office-based immunoassays for the diagnosis of Helicobacter pylori infection in children. Helicobacter 2002;7:205-209.
62. Okuda M, Miyashiro E, Koike M, et al. Serodiagnosis of Helicobacter pylori is not accurate for children below 10. Pediatr Int 2002;44:387-390.
63. Ho B, Marshall BJ. Accurate diagnosis of Helicobacter pylori. Serologic testing. Gastroenterol Clin North Am 2000;29:853-862.
64. Makristachis A, Pasching E, Schütze K, Wimmer M, Rotter M, Hirschl A. Detection of Helicobacter pylori in stool specimens by PCR and antigen enzyme immunoassay. J Clin Microbiol 1998;36:2771-2774.
65. Monteiro L, de Mascarel A, Sarrasqueta AM, Bergey B, Barberis C, Talby P, Roux D, Shouler L, Goldfain D, Lamouliatte H, Megraud F. Diagnosis of Helicobacter pylori infection: Noninvasive methods compared to invasive methods and evaluation of two new tests. Am J Gastroenterol 2001;96:353-358.
66. Oderda G, Rapa A, Ronchi B, Lerro P, Pastore M, Staiano A, de Angelis GL, Strisciuglio P. Detection of Helicobacter pylori in stool specimens by noninvasive antigen enzyme immunoassay in children: Multicenter Italian study. MBJ 2000;320:347-348.
67. Konstantopoulos N, Russmann H, Tasch C, Sauerwald T, Demmelmair H, Autenrieth I, Koletzko S. Evaluation of Helicobacter pylori stool antigen test (HpSA) for detection of Helicobacter pylori infection in children. Am J Gastroenterol 2001;96:677-683.
68. Wang YL, Sheu BS, Huang JJ, Yang HB. Noninvasive stool antigen assay can effectively screen Helicobacter pylori infection and assess success of eradication therapy in hemodialysis patients. Am J Kidney Dis 2001;38:98-103.
69. Roggero P, Bonfiglio A, Luzzani S, et al. Helicobacter pylori stool antigen test: A method to confirm eradication in children. J Pediatr 2002;140:775-777.
70. Kato S, Ozawa K, Okuda M, et al. Accuracy of the stool antigen test for the diagnosis of childhood Helicobacter pylori infection: A multicenter Japancse study. Am J Gastroenterol 2003;98:296-300.
71. Graham DY, Klein PD, Evans DJ Jr, Evans DG, Alpert LC, Opekun AR, Boutton TW. Campylobacter pylori detected noninvasively by the 13C-urea breath test. Lancet 1987;1:1174-1177.
72. Marshall BJ, Plankey MW, Hoffman SR, Boyd CL, Dye KR, Frierson HF Jr, Guerrant RL, McCallum R. A 20-minute breath test for Helicobacter pylori. Am J Gastroenterol 1991;86:438-445.
73. Kawasami E, Machado RS, Reber M, Patricio FRS. 13C-urea breath test with infrared spectroscopy for diagnosing Helicobacter pylori infection in children and adolescents. J Pediatr Gastroenterol Nutr 2002;35:39-43.
74. Chey WD. Accurate diagnosis of Helicobacter pylori. 14C-urea breath test. Gastroenterol Clin North Am 2000;29:895-902.
75. Slomianski A, Schubert T, Cutler AF. [13C] urea breath test to confirm eradication of Helicobacter pylori. Am J Gastroenterol 1995;90:224-226.
76. Shiotani A, Nurgalieva ZZ, Yamaoka Y, Graham DY. Helicobacter pylori. Med Clin North Am 2000;84:1125-1136.
77. Kato S, Takeyama J, Ebina K, Naganuma H. Omeprazole-based dual and triple regimens for Helicobacter pylori eradication in children. Pediatrics 1997;100(1):E3.
78. Gottrand F, Kalach N, Spyckerelle C, et al. Omeprazole combined with amoxicillin and clarithromycin in the eradication of the Helicobacter pylori in children with gastritis: A prospective randomized double-blind trial. J Pediatr 2001;139:664-668.
79. Oderda G, Cadranel S, Drumm B, Koletzko S. Announcing the creation of the Paediatric European register for treatment of Helicobacter pylori (PERTH). J Pediatr Gastroenterol Nutr 2001;33:526-567.
80. Dupont C, Kalach N, Raymond J. Helicobacter pylori and anti-microbial susceptibility in children. J Pediatr Gastroenterol Nutr 2003;36:311-313.
81. Feydt-Schmidt A, Russmann H, Lehn N, et al. Fluorescence in situ hybridization vs epsilometer test for detection of clarithromycin-susceptible and clarithromycin-resistant Helicobacter pylori strains in gastric biopsies for children. Aliment Pharmacol Ther 2002;16:2073-2079.
82. Del Giudice G, Covacci A, Telford JL, Montecucco C, Rappuoli R. The design of the vaccines against Helicobacter pylori and their development. Ann Rev Immunol 2001;19:523-563.