Effects of polymer modification of an anti-cancer drug with poly(ethylene oxide)

Macromolecular Symposia

Volumn 225, Issue , 2005, Pages 31-42

  Sohn, Jung Sun ^a   Jo, Byung Wook ^a   Hess, Michael ^b   Schwark, Kirsten ^b   Dehne, Stephanie ^b   Zähres, Manfred ^b  

^a Chosun University   (South Korea)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

mPEG paclitaxel; Simulation; Solution; Structure

Indexed keywords

CHEMICAL MODIFICATION; COMPUTER SIMULATION; DRUG PRODUCTS; MACROMOLECULES; MOLECULAR DYNAMICS; POLYETHYLENE OXIDES; SOLUBILITY; SOLUTIONS; TUMORS; WATER;

ANTI-CANCER DRUGS; MPEG-PACLITAXEL; STRUCTURE;

POLYMERS;

EID: 20844458831     PISSN: 10221360     EISSN: None     Source Type: Journal    
DOI: 10.1002/masy.200550704     Document Type: Conference Paper

References (20)

1. M. Suffness, Ann. Report Med. Chem. 1993, 18, 305
2. R. M. Straubinger, in: M. Suffness, (ed.) Taxol Science and Applications, CRC-Press, Boca Raton 1995 p. 237
3. Mazzo, D., Nguyen Hu. J. J., Pagniez, S., Denis, P., Am. J. Health Synth. Pharm. 1997, 54, 566
4. R. Panchagnula, Int. J. Pharm. 172, 1 (1998)
5. M.C. Wani, H.L. Taylor, M.E. Wall, P. Coggon, A.T. McPhail, J. Am. Chem Soc. 1981, 93, 2325
6. E.K. Rowinsky, L.A. Cazenave, R.C. Donehower, J. Natl Cancer Inst. 1990, 82, 1247
7. W.P. McGuire, E.K.Rowinsky, N.B. Rosenheim, F.C. Grumbine, D.S. Ettinger, D.K. Armstrong, Ann. Intern. Med. 1989, 111, 273
8. R.B. Greenwald, 1997 U.S. Pal. 5,614,549; (1999) US Pat 5,880,131; (1999) U.S Pat 5,965,566
9. Chung Li, 1999 US Pat 5,977,163
10. B.-W. Jo, 2000 Korean Patent 2000-0019873
11. B.-W. Jo, M. Hess, M. Zähres, Mater. Res. Innovat. 2003, 7, 178
12. M.Hess, J.-S. Sohn, S.-K.Choi, B.-W. Jo, Macromol Symp. 2003, 201, 163
13. J.-S. Sohn, S.-K. Choi, B.-W. Jo, M. Zähres, Mater. Res, Innovat. 2004, 8(4) in press
14. X. Shuai, T. Merdan, A. K. Schaper, F. Xi, T. Kissel, Bioconjugate Chem. 2004, 15, 441
15. E. Dobnik, thesis, Duisbuig, 1991
16. R B. Greenwald,Y. H. Choe, J. McGuire, C.D. Conover, Adv. Drug Delivery Rev. 2003, 55, 217
17. R.L. Juliano, Adv. Drug Del. Rev. 1988, 2, 31
18. P. Espagnol, P., Warren, P. B. Europhys. Lett. 1995, 30, 191
19. R.D.Grootland, P.B. Warren, J. Chem. Phys. 1997, 105, 4423
20. E. Ryjkina, H. Kuhn, H.F. Rehage, Müller, Peggau, J. Angew. Chem. 2002, 114(6), 1025