Altered expression of costimulatory molecules in patients with polymyositis

Journal of Clinical Neuromuscular Disease

Volumn 6, Issue 4, 2005, Pages 149-152

  Takamure, Miwa ^a   Murata, Ken Ya ^a   Sugie, Kazuma ^a   Ueno, Satoshi ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

Costimulatory molecule; Flow cytometry analysis; Polymyositis

Indexed keywords

BIOLOGICAL MARKER; CD28 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CORTICOSTEROID; IMMUNOSTIMULATING AGENT; IMMUNOSUPPRESSIVE AGENT;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DUCHENNE MUSCULAR DYSTROPHY; FEMALE; FLOW CYTOMETRY; HUMAN; IMMUNOSTIMULATION; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYMYOSITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE; T LYMPHOCYTE ACTIVATION;

EID: 20844457912     PISSN: 15220443     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.cnd.0000161529.91988.0b     Document Type: Article

References (12)

1. Dalakas MC. Immunopathogenesis of inflammatory myopathies. Ann Neurol. 1995;37:S74-S86.
2. Reiser H, Stadecker MJ. Costimulatory B7 molecules in the pathogenesis of infections and autoimmune disease. N Engl J Med. 1996;335:1369-1377.
3. Murata K, Dalakas MC. Expression of the costimulatory molecule BB-1, the ligands CTLA-4 and CD28, and their mRNA in inflammatory myopathies. Am J Pathol. 1999;155:453-460.
4. Bohan A. Peter JB. Polymyositis and dermatomyositis. N Engl J Med. 1975;292:344-347.
5. Amato AA, Griggs RC. Unicorns, dragons, polymyositis, and other mythological beasts. Neurology. 2003;61:288-290.
6. Behan WMH, Behan PO. Disturbance of regulatory lymphocyte subsets in polymyositis. Ann Neurol. 1984;15:112-114.
7. Iyer V, Lawton AR, Fenichel GM. T-cell subsets in polymyositis. Ann Neurol. 1983;13:452-453.
8. - T cells in healthy aging people, including centenarians. Immunology. 1996; 88:501-507.
9. Linsley PS, Bradshaw J, Urnes M, et al. CD28 engagement by B7/BB-1 induces transient down-regulation of CD28 synthesis and prolonged unresponsiveness to CD28 signaling. J Immunol. 1993; 150:3161-3169.
10. Teleshova N, Matusevicius D, Kivisäkk P, et al. Altered expression of costimulatory molecules in myasthenia gravis. Muscle Nerve. 2000;23:946-953.
11. Moosig F, Csernok E, Wang G, et al. Costimulatory molecules in Wegener's granulomatosis (WG): lack of expression of CD28 and preferential up-regulation of its ligands B7-1 (CD80) and B7-2 (CD86) on T cells. Clin Exp Immunol. 1998;114: 113-118.
12. Figarella-Branger D, Civatte M, Bartoli C, et al. Cytokines, chemokines, and cell adhesion molecules in inflammatory myopathies. Muscle Nerve. 2003; 28:659-682.