CD40 activation of B-CLL cells is associated with augmented intracellular levels of CD79b and increased BCR expression in a subset of patients [11]

Leukemia

Volumn 19, Issue 6, 2005, Pages 1099-1101

  Minuzzo, S ^a   Indraccolo, Stefano ^a,b   Tosello, V ^a   Piovan, E ^a   Cabrelle, E ^a   Trentin, L ^a   Semenzato, G ^a   Amadori, A ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY HOSPITAL OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; CD40 ANTIGEN; CD79B ANTIGEN; IMMUNOGLOBULIN M; INTERCELLULAR ADHESION MOLECULE 1; BCR PROTEIN, HUMAN; BREAKPOINT CLUSTER REGION PROTEIN; CD79 ANTIGEN; CD79B PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; ONCOPROTEIN; PROTEIN TYROSINE KINASE; TUMOR MARKER;

APOPTOSIS; CELLULAR DISTRIBUTION; CHRONIC LYMPHATIC LEUKEMIA; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; IMMUNOPHENOTYPING; IN VITRO STUDY; LETTER; MOLECULAR MECHANICS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; B CELL LEUKEMIA; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOPHYSIOLOGY;

ANTIGENS, CD; ANTIGENS, CD40; ANTIGENS, CD79; GENE EXPRESSION REGULATION, LEUKEMIC; HUMANS; IMMUNOPHENOTYPING; LEUKEMIA, B-CELL; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCR; TUMOR MARKERS, BIOLOGICAL;

EID: 20844456407     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2403772     Document Type: Letter

References (7)

1. Caligaris-Cappio F. B-chronic lymphocytic leukemia: a malignancy of anti-self B cells. Blood 1996; 87: 2615-2620.
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3. Alfarano A, Indraccolo S, Circosta, P, Minuzzo S, Vallario A, Zamarchi R et al An alternatively spliced form of CD79b gene may account for altered B-cell receptor expression in B-chronic lymphocytic leukemia. Blood 1999; 93: 2327-2335.
4. Payelle-Brogard B, Magnac C, Alcover A, Roux P, Dighiero G. Defective assembly of the B-cell receptor chains accounts for its low expression in B-chronic lymphocytic leukaemia. Br J Haematol 2002; 118: 976-985.
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6. Payelle-Brogard B, Magnac C, Oppezzo P, Dumas G, Dighiero G, Vuillier F. Retention and defective assembly of the B-cell receptor in the endoplasmic reticulum of chronic lymphocytic leukaemia B cells cannot be reverted upon CD40 ligand stimulation. Leukemia 2003; 17: 1196-1199.
7. Granziero L, Ghia P, Circosta P, Gottardi D, Strola G, Geuna M et al Survivin is expressed on CD40 stimulation and interfaces proliferation and apoptosis in B-cell chronic lymphocytic leukemia. Blood 2001; 97: 2777-2783.