Preferential migration of CD62L+ cells into the appendix in mice with experimental chronic colitis

European Surgical Research

Volumn 37, Issue 2, 2005, Pages 115-122

  Farkas, S A ^a,b   Hornung, M ^a   Sattler, Christine ^a   Steinbauer, M ^a   Anthuber, M ^a   Obermeier, F ^a   Herfarth, H ^a   Schlitt, H J ^a   Geissler, E K ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b UNIVERSITY HOSPITAL REGENSBURG   (Germany)

Author keywords

Adhesion molecules; Appendix CD62L+ cell migration; Experimental chronic colitis; In vivo microscopy

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APPENDIX; ARTICLE; CELL ACTIVATION; CELL LABELING; CELL MIGRATION; COLITIS; CONTROLLED STUDY; DISEASE COURSE; FEMALE; FLUORESCENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; T LYMPHOCYTE;

ADOPTIVE TRANSFER; ANIMALS; APPENDECTOMY; APPENDIX; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; CELL MOVEMENT; CHRONIC DISEASE; COLITIS; COLON; FEMALE; FLOW CYTOMETRY; INTEGRINS; L-SELECTIN; MICE; MICE, INBRED BALB C; MICE, SCID; WEIGHT GAIN;

EID: 20844455103     PISSN: 0014312X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000084543     Document Type: Article

References (28)

1. Fiocchi C: From immune activation to gut tissue injury: The pieces of the puzzle are coming together. Gastroenterology 1999;117:1238-1241.
2. Podolsky DK: Lessons from genetic models of inflammatory bowel disease. Acta Gastroenterol Belg 1997;60:163-165.
3. Sartor RB: Innate immunity in the pathogenesis and therapy of IBD. J Gastroenterol 2003; 38(suppl 15):43-47.
4. Koutroubakis IE, Vlachonikolis IG, Kouroumalis EA: Role of appendicitis and appendectomy in the pathogenesis of ulcerative colitis: A critical review. Inflamm Bowel Dis 2002;8: 277-286.
5. Lowenfels AB, Maisonneuve P: Appendectomy and protection against ulcerative colitis. N Engl J Med 2001;345:223-224.
6. Radford-Smith GL, Edwards JE, Purdie DM, Pandeya N, Watson M, Martin NG, Green A, Newman B, Florin TH: Protective role of appendicectomy on onset and severity of ulcerative colitis and Crohn's disease. Gut 2002;51: 808-813.
7. Andersson RE: Meta-analysis of the clinical and laboratory diagnosis of appendicitis. Br J Surg 2004:91:28-37.
8. Cosnes J, Carbonnel F, Beaugerie L, Blain A, Reijasse D, Gendre JP: Effects of appendicectomy on the course of ulcerative colitis. Gut 2002;51:803-807.
9. Naganuma M, Iizuka B, Torii A, Ogihara T, Kawamura Y, Ichinose M, Kojima Y, Hibi T, Tokyo Gut Club: Appendectomy protects against the development of ulcerative colitis and reduces its recurrence: Results of a multicenter case-controlled study in Japan. Am J Gastroenterol 2001;96:1123-1126.
10. Mizoguchi A, Mizoguchi E, Chiba C, Bhan AK: Role of appendix in the development of inflammatory bowel disease in TCR-alpha mutant mice. J Exp Med 1996;184:707-715.
11. Krieglstein CF, Cerwinka WH, Laroux FS, Grisham MB, Schurman G, Bruwer M, Granger DN: Role of appendix and spleen in experimental colitis. J Surg Res 2001;101:166-175.
12. Mudter J, Wirtz S, Galle PR, Neurath MF: A new model of chronic colitis in SCID mice induced by adoptive transfer of CD62L+ CD4+ T cells: Insights into the regulatory role of interleukin-6 on apoptosis. Pathobiology 2002;70:170-176.
13. Powrie F, Correa-Oliveira R, Mauze S, Coffman RL: Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity. J Exp Med 1994;179:589-600.
14. Bregenholt S, Brimnes J, Reimann J. Claesson MH: Accumulation of immunoglobulin-containing cells in the gut mucosa and presence of faecal immunoglobulin in severe combined immunodeficient (seid) mice with T cell-induced inflammatory bowel disease (IBD). Clin Exp Immunol 1998;114:19-25.
15. Farkas S, Herfarth H, Rössle M, Schroeder J, Steinbauer M, Guba M, Beham A, Schölmerich J, Jauch KW, Anthuber M: Quantification of mucosal leucocyte endothelial cell interaction by in vivo fluorescence microscopy in experimental colitis in mice. Clin Exp Immunol 2001;126:250-258.
16. Harris AG, Hecht R, Peer F, Nolte D, Messmer K: An improved intravital microscopy system. Int J Microcirc Clin Exp 1997;17:322-327.
17. Obermeier F, Dunger N, Strauch UG, Grunwald N, Herfarth H, Schölmerich J, Falk W: Contrasting activity of cytosin-guanosin dinucleotide oligonucleotides in mice with experimental colitis. Clin Exp Immunol 2003;134: 217-224.
18. Davies MD, Parrott DM: Preparation and purification of lymphocytes from the epithelium and lamina propria of murine small intestine. Gut 1981;22:481-488.
19. Briskin M, Winsor-Hines D, Shyjan A, Cochran N, Bloom S, Wilson J, McEvoy LM, Butcher EC, Kassam N, Mackay CR, Newman W, Ringler DJ: Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue. Am J Pathol 1997;151:97-110.
20. Shand A, Forbes A: Potential therapeutic role for cytokine or adhesion molecule manipulation in Crohn's disease: In the shadow of infliximab? Int J Colorectal Dis 2003;18:1-11.
21. Von Andrian UH, Engelhardt B: Alpha4 integrins as therapeutic targets in autoimmune disease. N Engl J Med 2003;348:68-72.
22. Von Andrian UH, Mempel TR: Homing and cellular traffic in lymph nodes. Nat Rev Immunol 2003;3:867-878.
23. Kawachi S, Morise Z, Jennings S, Conner E, Cockrell A, Laroux FS, Chervanak R, Wolcott M, van der Heyde HC, Gray L, Feng L, Granger N, Specian RA, Grisham MB: Cytokine and adhesion molecule expression in SCID mice reconstituted with CD4+ T cells. Inflam Bowel Dis 2000;6:171-180.
24. Lehnert K, Print CG, Yang Y, Krissansen GW: MAdCAM-1 costimulates T cell proliferation exclusively through integrin alpha4-beta7, whereas VCAM-1 and CS-1 peptide use alpha4-beta1: Evidence for 'remote' costimulation and induction of hyperresponsiveness to B7 molecules. Eur J Immunol 1998;28:3605-3615.
25. Pachynski RK, Wu SW, Gunn MD, Erle DJ: Secondary lymphoid-tissue chemokine (SLC) stimulates integrin alpha 4 beta 7-mediated adhesion of lymphocytes to mucosal addressin cell adhesion molecule-1 (MAdCAM-1) under flow. J Immunol 1998;161:952-956.
26. Picarella D, Hurlbut P, Rottman J, Shi X, Butcher E, Ringler DJ: Monoclonal antibodies specific for beta 7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) reduce inflammation in the colon of scid mice reconstituted with CD45RBhigh CD4+ T cells. J Immunol 1997;158:2099-2106.
27. Liu Z, Geboes K, Colpaert S, Overbergh L, Mathieu C, Heremans H, de Boer M, Boon L, D'Haens G, Rutgeerts P, Ceuppens JL: Prevention of experimental colitis in SCID mice reconstituted with CD45RBhigh CD4+ T cells by blocking the CD40-CD154 interactions. J Immunol 2000;164:6005-6014.
28. Sandborn WJ, Yednock TA: Novel approaches to treating inflammatory bowel disease: Targeting alpha-4 integrin. Am J Gastroenterol 2003; 98:2372-2382.