Outcome in elderly patients undergoing primary coronary intervention for acute myocardial infarction: Results from the controlled abciximab and device investigation to lower late angioplasty complications (CADILLAC) trial

Circulation

Volumn 110, Issue 12, 2004, Pages 1598-1604

  Guagliumi, Giulio ^a   Stone, Gregg W ^b,j   Cox, David A ^c   Stuckey, Thomas ^d   Tcheng, James E ^e   Turco, Mark ^f   Musumeci, Giuseppe ^a   Griffin, John J ^g   Lansky, Alexandra J ^b   Mehran, Roxana ^b   Grines, Cindy L ^h   Garcia, Eulogio ⁱ  

^a OSPEDALI RIUNITI   (Italy)

^b NewYork Presbyterian Hospital   (United States)

^c Mid Carolina Cardiology   (United States)

^d MOSES H CONE MEMORIAL HOSPITAL   (United States)

^e DUKE CLINICAL RESEARCH INSTITUTE   (United States)

^f WASHINGTON ADVENTIST HOSPITAL   (United States)

^g Sentara Virginia Beach General Hospital   (United States)

^h WILLIAM BEAUMONT HOSPITAL   (United States)

ⁱ HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^j CARDIOVASCULAR RESEARCH FOUNDATION   (United States)

more..

Author keywords

Myocardial infarction; Platelet aggregation inhibitors; Stents

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FIBRINOGEN RECEPTOR ANTAGONIST; THIENO[2,3 B]PYRIDINE DERIVATIVE;

ACUTE HEART INFARCTION; ADULT; AGED; AGING; ARTICLE; BLEEDING; CEREBROVASCULAR ACCIDENT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY STENT; FEMALE; HEART MUSCLE REVASCULARIZATION; HEART REINFARCTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOMES RESEARCH; PERCUTANEOUS CORONARY INTERVENTION; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; PRIORITY JOURNAL; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL; THROMBOSIS;

ADRENERGIC BETA-ANTAGONISTS; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; ANTIBODIES, MONOCLONAL; ASPIRIN; CEREBROVASCULAR ACCIDENT; COHORT STUDIES; COMBINED MODALITY THERAPY; CORONARY ANGIOGRAPHY; CORONARY RESTENOSIS; FEMALE; HEMORRHAGE; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; LIFE TABLES; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PLATELET AGGREGATION INHIBITORS; PROPORTIONAL HAZARDS MODELS; PYRIDINES; STENTS; TREATMENT OUTCOME;

EID: 20844449244     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000142862.98817.1F     Document Type: Article

References (27)

1. Kaplan KL, Fitzpatrick P, Cox C, et al. Use of thrombolytic therapy for acute myocardial infarction: effects of gender and age on treatment rates. J Thromb Thrombolysis. 2002;13:21-26.
2. Lichtman JH, Krumholz HM, Wang Y, et al. Risk and predictors of stroke after myocardial infarction among the elderly. Circulation, 2002;105: 1082-1087.
3. Barakat K, Wilkinson P, Deaner, et al. How should age effect management of acute myocardial infarction? A prospective cohort study. Lancet. 1999; 353:955-959.
4. Batchelor WB, Anstrom KJ, Muhlbaier LH, et al. Contemporary outcome trends in the elderly undergoing percutaneous coronary interventions: results in 7,472 octogenarians. J Am Coll Cardiol. 2000;36:723-730.
5. Graham MM, Ghali WA, Paris PD, et al. Survival after coronary revascularization in the elderly. Circulation. 2002;105:2378-2384.
6. Maggioni AP, Maseri A, Fresco C, et al. Age-related increase in mortality among patients with first myocardial infarctions treated with thrombolysis. N Engl J Med. 1993;329:1442-1448.
7. Barren HV, Bowlby LJ, Breen T, et al. Use of the reperfusion therapy for acute myocardial infarction in the United States: data from the National Registry of Myocardial Infarction 2. Circulation. 1998;97:1150-1156.
8. Lee P, Alexander K, Hammil B, et al. Representation of elderly persons and women in published randomized trials of acute coronary syndromes. JAMA. 2001;286:708-713.
9. Gurwitz JH, Col NF, Avron J. The exclusion of the elderly and women from clinical trials in acute myocardial infarction. JAMA. 1992;268:1417-1422.
10. Berger AK, Schulman KA, Gersh BJ, et al. Primary coronary angioplasty vs thrombolysis for the management of acute myocardial infarction in elderly patients. JAMA. 1999;282:341-348.
11. Antoniucci D, Valenti R, Santoro GM, et al. Systematic primary angioplasty in octogenarian and older patients. Am Heart J. 1999;138:670-674.
12. Stone GW, Grines CL, Cox DA, et al. Comparison of angioplasty with stenting, with or without abciximab, in acute myocardial infarction. N Engl J Med. 2002;346:957-966.
13. Lansky A, Popma J. Qualitative and quantitative angiography. In: Topol EJ, ed. Textbook of Interventional Cardiology. 3rd ed. Philadelphia, Pa: WB Saunders; 1999:725-747.
14. De Boer MJ, Ottervanger JP, van't Hof AW, et al. Reperfusion therapy in elderly patients with acute myocardial infarction. J Am Coll Cardiol. 2002; 39:1723-1728.
15. Holmes DR, White HD, Pieper KS. Effect of age on outcome with primary angioplasty versus thrombolysis. J Am Coll Cardiol. 1999;33:412-419.
16. Soumerai SB, McLaughlin TJ, Ross-Degnan D, et al. Effectiveness of thrombolytic therapy for acute myocardial infarction in the elderly: cause for concern in the old-old. Arch Intern Med. 2002;162:561-568.
17. Berger AK, Radford MJ, Wang Y, et al. Thrombolytic therapy in older patients. J Am Coll Cardiol. 2000;36:366-374.
18. Shihara M, Tsutsui H, Tsuchihashi M, et al. In-hospital and one-year outcomes for patients undergoing percutaneous coronary intervention for acute myocardial infarction. Am J Cardiol. 2002;90:932-936.
19. Suryapranata H, van't Hof AW, Hoorntje JC, et al. Randomized comparison of coronary stenting with balloon angioplasty in selected patients with acute myocardial infarction. Circulation. 1998;97:2502-2505.
20. Stone GW, Brodie BR, Griffin JJ, et al. Prospective, multicenter study of the safety and feasibility of primary stenting in acute myocardial infarction: in-hospital and 30-day results of the PAMI stent pilot trial. J Am Coll Cardiol. 1998;31:23-30.
21. Montalescot G, Barragan P, Wittember O, et al. Platelet glycoprotein IIb/IIIa inhibition with coronary stenting for acute myocardial infarction. N Engl J Med. 2001;344:1895-1903.
22. Tcheng JE, Kandzari DE, Grines CL, et al. Benefits and risks of abciximab use in primary angioplasty for acute myocardial infarction. Circulation. 2003;108:1316-1323.
23. Keeley EC, Boura JA, Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials. Lancet. 2003;361:13-20.
24. DeGeare VS, Stone GW, Grines L, et al. Angiographic and clinical characteristics associated with increased in-hospital mortality in elderly patients with acute myocardial infarction undergoing percutaneous intervention. Am J Cardiol. 2000;86:30-34.
25. Anversa P, Kajstura J. Ventricular myocytes are not terminally differentiated in the adult mammalian heart. Circ Res. 1998;83:1-14.
26. Lesnefsky EJ, Gallo DS, Ye J, et al. Aging increases ischemia-reperfusion injury in the isolated, buffer-perfused heart. J Lab Clin Med. 1994;124: 843-851.
27. Hannan EL, Racz MJ, Arani DT, et al. Short- and long-term mortality for patients undergoing primary angioplasty for acute myocardial infarction. J Am Coll Cardiol. 2000;36:1194-1201.