Phytochelatin is not a primary factor in determining copper tolerance

Journal of Plant Biology

Volumn 48, Issue 1, 2005, Pages 32-38

  Lee, Sangman ^a   Beom, Sik Kang ^a  

^a Kyungpook National University   (South Korea)

Author keywords

Arabidopsis; Cad1; Cad2; Cadmium; Copper; Phytochelatin

Indexed keywords

ARABIDOPSIS; ARABIDOPSIS THALIANA; SACCHAROMYCES CEREVISIAE;

EID: 20744448111     PISSN: 12269239     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03030562     Document Type: Article

References (32)

1. Clemens S (2001) Molecular mechanisms of plant metal tolerance and homeostasis. Planta 212: 475-486
2. Clemens S, Kim EJ, Neumann D, Schroeder JI (1999) Tolerance to toxic metals by a gene family of phytochelatin synthases from plants and yeast. EMBO J 18: 3325-3333
3. Cobbett CS (2000a) Phytochelatins and their roles in heavy metal detoxification. Plant Physiol 123: 825-832
4. Cobbett CS (2000b) Phytochelatin biosynthesis and function in heavy-metal detoxification. Curr Opin Plant Biol 3: 211-216
5. Cobbett CS, Goldsbrough P (2002) Phytochelatins and metallothioneins: Roles in heavy metal detoxification and homeostasis. Annu Rev Plant Biol 53: 159-182
6. Cobbett CS, May MJ, Howden R, Rolls B (1998) The glutathione-deficient, cadmium-sensitive mutant, cad2-1, of Arabidopsis thaliana is deficient in γ-glutamylcysteine synthetase. Plant J 16: 73-78
7. de Miranda JR, Thomas MA, Thurman DA, Tomsett AB (1990) Metallothionein genes from the flowering plant Mimulus guttatus. FEBS Lett 260: 277-280
8. de Vos CHRD, Vonk MJ, Vooijs R, Schat H (1992) Glutathione depletion due to copper induced phytochelatin synthesis causes oxidative stress in Silene cucubalus. Plant Physiol 98: 853-858
9. Grill E, Loffler S, Winnacker E-L, Zenk MH (1989) Phytochelatins, the heavy-metal-binding peptides of plants, are synthesized from glutathione by a specific γ-glutamylcysteine dipeptidyl transpeptidase (phytochelatin synthase). Proc Natl Acad Sci USA 86: 6838-6842
10. Grill E, Winnacker EL, Zenk MH (1985) Phytochelatins: The principal heavy-metal complexing peptides of higher plants. Science 230: 674-676
11. Grill E, Winnacker EL, Zenk MH (1987) Phytochelatins, a class of heavy-metal-binding peptides from plants, are functionally analogous to metallothioneins. Proc Natl Acad Sci USA 84: 439-443
12. Ha S-B, Smith AP, Howden R, Dietrich WM, Bugg S, OConell MJ, Goldsbrough PB, Cobbett CS (1999) Phytochelatin synthase genes from Arabidopsis and the yeast, Schizosaccharomyces pombe. Plant Cell 11: 1153-1164
13. Hartley-Whitaker J, Ainsworth G, Meharg AA (2001) Copper- and arsenate-induced oxidative stress in Holcus lanatus L. clones with differential sensitivity. Plant Cell Environ 24: 713-722
14. Howden R, Cobbett CS (1992) Cadmium-sensitive mutants of Arabidopsis thaliana. Plant Physiol 99: 100-107
15. Howden R, Goldsbrough PB, Anderson CR, Cobbett CS (1995) Cadmium-sensitive, cad1 mutants of Arabidopsis thaliana are phytochelatin deficient. Plant Physiol 107: 1059-1066
16. Lee S, Korban SS (2002) Transcriptional regulation of Arabidopsis thaliana phytochelatin synthase (AtPCS1) by cadmium during early stages of plant development. Planta 215: 689-693
17. Lee S, Moon JS, Domier LL, Korban SS (2002) Molecular characterization of phytochelatin synthase expression in transgenic Arabidopsis. Plant Physiol Biochem 40: 727-733
18. Lee S, Moon JS, Ko T-S, Petro D, Goldsbrough PB, Korban SS (2003a) Overexpression of Arabidopsis phytochelatin synthase paradoxically leads to hypersensitivity to cadmium stress. Plant Physiol 131: 656-663
19. Lee S, Petro D, Moon JS, Ko T-S, Goldsbrough PB, Korban SS (2003b) Higher levels of ectopic expression of Arabidopsis phytochelatin synthase do not lead to increased cadmium tolerance and accumulation. Plant Physiol Biochem 41: 903-910
20. Murashige T, Skoog T (1962) A revised medium for growth and bioassays with tobacco tissue cultures. Physiol Plant 15: 473-479
21. Murphy A, Taiz L (1995) Comparison of metallothionein gene expression and non-protein thiols in ten Arabidopsis ecotypes. Plant Physiol 109: 945-954
22. Oven M, Page JE, Zenk MH, Kutchan TM (2002) Molecular characterization of the homo phytochelatin synthase of soybean Glycine max. J Biol Chem 277: 4747-4754
23. Rauser WE (1990) Phytochelatins. Annu Rev Biochem 59: 61-86
24. Rauser WE (1999) Structure and function of metal chelators produced by plants: The case for organic acids, amino acids, phytin and metallothioneins. Cell Biochem Biophysics 32: 19-48
25. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular Cloning: A Laboratory Manual, Ed 2. Cold Spring Harbor Laboratory Press, NY
26. Sandrine S-M, Stephan C, Patrick C, Catherine L-P, Doan-Trung L, Gilles P (2003) Enhanced toxic metal accumulation in engineered bacterial cells expressing Arabidopsis thaliana phytochelatin synthase. Appl Environ Microbiol 69: 490-494
27. Scarano G, Morelli E (1998) Polarographic behavior of metal phytochelatin complexes. Electroanalysis 10: 3943
28. van Hoof NALM, Hassinen VH, Hakvoort HWJ, Ballintijn KF, Schat H, Verkleij JAC, Ernst WHOE, Karenlampi SO, Tervanhauta AI (2001) Enhanced copper tolerance in Silene vulgaris (Moench) garcke populations from copper mine is associated with increased transcript levels of a 2b-type metallothionein gene. Plant Physiol 126: 1519-1526
29. van Vliet C, Anderson CR, Cobbett CS (1995) Copper-sensitive mutant of Arabidopsis thaliana. Plant Physiol 109: 871-878
30. Vatamaniuk OK, Mari S, Lu Y-P, Rea PA (1999) AtPCS1, a phytochelatin synthase from Arabidopsis: Isolation and in vitro reconstitution. Proc Natl Acad Sci USA 96: 7110-7115
31. Vatamaniuk OK, Mari S, Lu Y-P, Rea PA (2000) Mechanism of heavy metal ion activation of phytochelatin (PC) synthase. J Biol Chem 275: 31451-31459
32. Zenk MH (1996) Heavy metal detoxification in higher plants: A review. Gene 179: 21-30