The effect of intramuscular injections of boar pheromone 5α-androstenol on the hormonal regulation of the estrous cycle in hypoosmatic gilts

Polish Journal of Veterinary Sciences

Volumn 8, Issue 2, 2005, Pages 85-91

  Stefanczyk Krzymowska S ^a   Wasowska B ^a   Skipor, J ^a  

^a INSTITUTE OF ANIMAL REPRODUCTION AND FOOD RESEARCH   (Poland)

Author keywords

Boar pheromone; Estrous cycle; LH; Oxytocin; Sows; Steroid hormones

Indexed keywords

5ALPHA ANDROSTENOL; ESTRADIOL; LUTEINIZING HORMONE; OXYTOCIN; PHEROMONE DERIVATIVE; PROGESTERONE; TESTOSTERONE; UNCLASSIFIED DRUG; ZINC SULFATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; ESTRADIOL BLOOD LEVEL; ESTRUS CYCLE; FEMALE; HORMONAL REGULATION; HORMONE RELEASE; HUMORAL IMMUNITY; JUGULAR VEIN; LUTEINIZING HORMONE BLOOD LEVEL; NONHUMAN; NOSE CAVITY; OLFACTORY SYSTEM; OXYTOCIN BLOOD LEVEL; PROGESTERONE BLOOD LEVEL; SWINE; TESTOSTERONE BLOOD LEVEL;

ANDROSTENOLS; ANIMALS; ESTRADIOL; ESTROUS CYCLE; ESTRUS SYNCHRONIZATION; FEMALE; INJECTIONS, INTRAMUSCULAR; LUTEINIZING HORMONE; NASAL MUCOSA; OXYTOCIN; PHEROMONES; PROGESTERONE; SWINE; TESTOSTERONE; TREATMENT OUTCOME;

ANIMALIA; SUS SCROFA;

EID: 20744442697     PISSN: 15051773     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Booth WD (1982) Steroid hormone and pheromone binding proteins in the submaxillary gland and saliva of pig. In: Breipohl, W (ed): Olfaction and Endocrine Regulation. IRL Press, London, pp 353-356.
2. Booth WD, Signoret JP (1992) Olfaction and reproduction in ungulates. Oxford Rev Reprod 14: 265-301.
3. Brooks PH, Colle DJA (1970) Effect of the presence of the boar on attainment of puberty in the gilts. J Reprod Fertil 23: 435-440.
4. Chuah MI, Tennet R, Jacobs I (1995) Response of olfactory Schwann cells to intranasal zink sulfate irrigation. J Neurosci Res 42: 470-478.
5. Craig AJ, Lopez F, Samson WK, Negro-Vilar A (1990) Physiologically important role for central oxytocin in the preovulatory release of luteinizing hormone. Neurosci Lett 120: 256-258.
6. Dorries KM, Adkins-Regen E, Halpern BP (1997) Sensitivity and behavioral responses to the pheromone androstenone are not mediated by the vomeronasal organ in domestic pigs. Brain Behav Evolut; 49: 53-62.
7. Glei M, Schlegel W, Straube D, Blankenger J (1989) Untersuchungen zur Beeinflussung des Pubertatseintrittes von Jungsauen mittels maskuliner Stimuli. Archiv Tierzucht 32: 173-179.
8. 4 irrigation on behavior, biochemistry and morphology. Brain Res 140: 313-319.
9. Hotchkiss SB, Atkinson LE, Knobil E (1971) Time course of serum estrogen and luteinizing hormone (LH) concentration during the menstrual cycle of the rhesus monkey. Endocrinology 89: 177-183.
10. Kanitz E, Schnaider F, Brussow KP, Schmidt HE, Kitzig M, Blodow G (1991) Konzentrationen von Prolactin, LH, Estradiol-17β und Progesteron beim Schwein nach biotechnischer Stimulation mit PMSG, HCG und Suidor®. Arch exper Vet med Leipzig 45: 55-66.
11. Karlbom I (1982) Attainment of puberty in female pigs: Influence of boar stimulation. Anim Reprod Sci 4: 313-319.
12. Kirkwood RN, Hughes PE, Both WD (1983) The influence of boar-related odours on puberty attainment in gilts. Anim Prod 36: 131-136.
13. Kotwica J, Krzymowski T, Dȩbek J (1978) Cannulation of veins in pig for endocrinous studies (In Polish) Med Weter 2: 118-120.
14. Kotwica J, Skarżyński D (1993) Influence of oxytocin removal from corpus luteum on secretory function and duration of the estrous cycle in cattle. J Reprod Fertil 97: 411-417.
15. Kotwica J, Williams GL, Marchello MJ. (1982) Countercurrent transfer of testosterone by the ovarian vascular pedicle of the cow: Evidence for a relationship to follicular steroidogenesis. Biol Reprod 27: 778-789.
16. Krzymowski T, Grzegorzewski W, Stefańczyk-Krzymowska S, Skipor J, Wa̧sowska B (1999) Humoral pathway for transfer of the boar pheromone, androstenol, from the nasal mucosa to the brain and hypophysis of gilts. Theriogenology 52: 1225-1240.
17. Krzymowski T, Stefańczyk-Krzymowska S, Grzegorzewski W, Skipor J, Wa̧sowska B (2001) A possible humoral pathway for the priming action of the male pheromone androstenol on female pigs. In: Marchlewska-Koj et al. (eds) Chemical Signals in Vertebrates 9, Kluwer Academic/Plenum Publisher, New York, pp 114-124.
18. Malvaney BD Heist HE (1971) Regeneration of rabbit olfactory epithelium. Am J Anat 131: 241-252.
19. Mattioli M, Galeati G, Conte F, Seren E (1986) Effect of 5α-androst-16-en-3-one on oxytocin release in oestrous sows. Theriogenology; 25:399-403.
20. Pearce GP, Paterson AM (1992) Physical contact with the boar is required for maximum stimulation of puberty in gilt because it allows transfer of boar pheromone and not because it induces cortisol release. Anim Reprod Sci 27: 209-224.
21. Schams D, Schmidt-Polex B, Kruse V (1979) Oxytocin determination by radioimmunoassay in cattle. Acta Endocrinol 92: 258-270.
22. Schultz EW (1960) Repair of the olfactory mucosa with special reference to regeneration of olfactory cells (sensory neurons). Am J Pathol 37: 1-19.
23. Signoret JP (1970) Reproductive behaviour of pigs. J Reprod Fertil; Suppl 11: 5-117.
24. Stefańczyk-Krzymowska S, Grzegorzewski W, Skipor J, Wa̧sowska B, Krzymowski T (1997) Involvement of adrenoceptors in the ovarian vascular pedicle in the regulation of counter current transfer of steroid hormones to the arterial blood supplying the oviduct and uterus. Brit J Pharmacol 120: 763-768.
25. Stefańczyk-Krzymowska S, Krzymowski T, Grzegorzewski W, Wa̧sowska B, Skipor J (2000) Humoral pathway for local transfer of the priming pheromone androstenol from the nasal cavity to the brain and hypophysis in anaesthetized gilts. Exp Physiol 85: 801-809.
26. Stefańczyk-Krzymowska S, Krzymowski T, Wasowska B, Jana B, Słomiński J (2003) Intramuscular injections of male pheromone 5α-androstenol change the secretory ovarian function in gilts during sexual maturation. Reprod Biol 3: 243-259.
27. Stefańczyk-Krzymowska S, Skipor J, Grzegorzewski W, Wa̧sowska B, Krzymowski T (1994) Local increase of ovarian steroid hormone concentration in blood supplying the uterus and oviduct in anaeshetized and conscious gilts. Anim Reprod Sci 37: 35-41.
28. Stefańczyk-Krzymowska S, Wa̧sowska B, Jana B (2002) Boar pheromone may affect the ovarian morphology in cycling gilts by humoral pathway. Folia Histochem Cyto 40: 57-58.
29. Szafrańska B, Ziȩcik AJ, Okrasa S (2002) Primary antisera against selected steroids or proteins and secondary antisera against γ-globulins - an available tool for studies of reproductive processes. Reprod Biol 2: 187-203.
30. Ziȩcik A, Goralska M, Krzymowski T, Pogorzelski K (1978) Isolation and purification of porcine LH for radioimmunoassay and receptor assay. Bull Pol Acad Sci, Biol Sci 26: 739-744.