The effects of hormone replacement on the biomechanical properties of the uterosacral and round ligaments in the monkey model

American Journal of Obstetrics and Gynecology

Volumn 192, Issue 5 SPEC. ISS., 2005, Pages 1741-1751

  Vardy, Michael D ^a,b,c   Gardner, Thomas R ^a   Cosman, Felicia ^a,b   Scotti, Richard J ^e   Mikhail, Magdy S ^c   Preiss Bloom, A Orahn ^a   Williams, J Koudy ^d   Cline, J Mark ^d   Lindsay, Robert ^a,b  

^a Columbia College of Physicians and Surgeons ^*  (United States)

^b HELEN HAYES HOSPITAL   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d WAKE FOREST SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Biomechanics; Estrogen; Ligament; Monkey; Pelvic organ prolapse

Indexed keywords

CONJUGATED ESTROGEN; DRUG DERIVATIVE; ESTROGEN; ETHINYLESTRADIOL; HORMONE; MEDROXYPROGESTERONE ACETATE; NORETHISTERONE; NORETHISTERONE ACETATE;

ANIMAL; ARTICLE; BIOMECHANICS; DRUG EFFECT; DRUG POTENTIATION; ELASTICITY; FEMALE; FEMALE GENITAL SYSTEM; LIGAMENT; MACACA; OVARIECTOMY; PHYSIOLOGY; TENSILE STRENGTH; UTERUS;

ANIMALS; BIOMECHANICS; DRUG SYNERGISM; ELASTICITY; ESTROGENS; ESTROGENS, CONJUGATED (USP); ETHINYL ESTRADIOL; FEMALE; HORMONES; LIGAMENTS; MACACA FASCICULARIS; MEDROXYPROGESTERONE 17-ACETATE; NORETHINDRONE; OVARIECTOMY; ROUND LIGAMENT; TENSILE STRENGTH; UTERUS;

EID: 20644455343     PISSN: 00029378     EISSN: 10976868     Source Type: Journal    
DOI: 10.1016/j.ajog.2004.10.639     Document Type: Article

References (10)

1. Mokrzycki ML, Mittal K, Smilen SW, Blechman AN, Porges RF, Demopolous RI. Estrogen and progesterone receptors in the uterosacral ligament. Obstet Gynecol 1997;90:402-4. (Pubitemid 27357932)
2. Chen GD, Oliver RH, Leung BS, Lin LY, Yeh J. Estrogen receptor alpha and beta expression in the vaginal walls and uterosacral ligaments of premenopausal and postmenopausal women. Fertil Steril 1999;71:1099-102. (Pubitemid 29252503)
3. Rasanen T, Messner K. Estrogen-dependent tensile properties of the rabbit knee medial collateral ligament. Scand J Med Sci Sports 2000;10:20-7.
4. Vardy M, Lindsay R, Scotti RJ, Mikhail M, Richart R, Nieves J, et al. Short term urogenital effects of raloxifene, tamoxifen, and estrogen. Am J Obstet Gynecol 2003;189:81-8. (Pubitemid 36886529)
5. Cline JM. Surgically post-menopausal monkeys for assessing risk and benefits to the breast and endometrium. Menopausal Med 2001;10:2-6.
6. Cline JM, Söderqvist G, Register TC, Williams JK, Adams MR, Von Schoultz B. Assessment of hormonally active agents in the reproductive tract of female nonhuman primates. Toxicol Pathol 2001;29:84-90. (Pubitemid 32127326)
7. Suparto IH, Williams JK, Cline JM, Anthony MS, Fox JL. Contrasting effects of two hormone replacement therapies on the cardiovascular and mammary gland outcomes in surgically postmenopausal monkeys. Am J Obstet Gynecol 2003;188:1132-40. (Pubitemid 36589081)
8. Akizuki S, Mow VC, Muller F, Pita JC, Howell DS, Manicourt DH. Tensile properties of human knee joint cartilage: I. Influence of ionic concentrations, weight bearing and fibrillation on the tensile modulus. J Ortho Res 1986;4:379-92. (Pubitemid 17227720)
9. Boyles S, Weber A, Meyn L. Procedures for pelvic organ prolapse in the United States, 1979-1997.AmJ Obstet Gynecol 2003;188:108-15. (Pubitemid 36135605)
10. Waetjen LE, Subak LL, Shen H, Lin F, Wang TH, Vittinghoff E, et al. Stress urinary incontinence surgery in the United States. Obstet Gynecol 2003;101:671-6. (Pubitemid 36390054)