Outcome of 60 neonates who had ARED flow prenatally compared with a matched control group of appropriate-for-gestational age preterm neonates

Ultrasound in Obstetrics and Gynecology

Volumn 25, Issue 6, 2005, Pages 566-572

  Hartung, J ^a,b   Kalache, K D ^a   Heyna, C ^a   Heling, K S ^a   Kuhlig, M ^a   Wauer, R ^a   Bollmann, R ^a   Chaoui, R ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b Praxis für Pränatale Diagnostik und Ultraschall ^*  (Germany)

Author keywords

ARED flow; Doppler; Fetal outcome; Gestational age; Prematurity; Umbilical artery

Indexed keywords

ABSENT OR REVERSED ENDDIASTOLIC FLOW; APGAR SCORE; ARTERIAL PH; ARTERY BLOOD FLOW; ARTICLE; BIRTH WEIGHT; BRAIN HEMORRHAGE; CARDIOTOCOGRAPHY; CONTROLLED STUDY; DOPPLER FLOWMETRY; ENTEROPATHY; FETUS; FETUS OUTCOME; GESTATIONAL AGE; HUMAN; INTRAUTERINE GROWTH RETARDATION; LEUKOMALACIA; LUNG DYSPLASIA; MAJOR CLINICAL STUDY; NECROTIZING ENTEROCOLITIS; NEUROLOGIC EXAMINATION; PATENT DUCTUS ARTERIOSUS; PERINATAL MORBIDITY; PERINATAL MORTALITY; PREMATURITY; PRENATAL SCREENING; PRIORITY JOURNAL; RESPIRATORY DISTRESS SYNDROME; UMBILICAL ARTERY; UMBILICAL CORD BLOOD FLOW; VEIN BLOOD FLOW;

BIRTH WEIGHT; BLOOD FLOW VELOCITY; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; FEMALE; GESTATIONAL AGE; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; LASER-DOPPLER FLOWMETRY; PREGNANCY; PREGNANCY COMPLICATIONS, CARDIOVASCULAR; PREGNANCY OUTCOME; RETROSPECTIVE STUDIES; STATISTICS, NONPARAMETRIC; UMBILICAL ARTERIES;

EID: 20644449479     PISSN: 09607692     EISSN: None     Source Type: Journal    
DOI: 10.1002/uog.1906     Document Type: Article

References (28)

1. Soothill PW, Nicolaides KH, Campbell S. Prenatal asphyxia, hyperlacticaemia, hypoglycemia and erythroblastosis in growth retarded fetuses. Br Med J 1987; 294: 1051-1053.
2. Kurkinen-Räty M, Kivela A, Jouppila P. The clinical significance of an absent end-diastolic velocity in the umbilical artery detected before the 34th week of pregnancy. Acta Obstet Gynecol Scand 1997; 76: 398-404.
3. Montenegro N, Santos F, Tavares E, Matias A, Barros H, Leite LP. Outcome of 88 pregnancies with absent or reversed end-diastolic blood flow (ARED flow) in the umbilical arteries. Eur J Obstet Gynecol Reprod Biol 1998; 79: 43-46.
4. Barker DJ. The long-term outcome of retarded fetal growth. Clin Obstet Gynecol 1997; 40: 853-863.
5. Hecher K, Campbell S, Doyle P, Harrington K. Nicolaides K. Assessment of fetal compromise by Doppler ultrasound investigation of the fetal circulation. Arterial, intracardiac, and venous blood flow velocity studies. Circulation 1995; 91: 129-138.
6. Hecher K, Bilardo CM, Stigter RH, Ville Y, Hackeloer BJ, Kok HJ, Senat MV, Visser GH. Monitoring of fetuses with intrauterine growth restriction: a longitudinal study. Ultrasound Obstet Gynecol 2001; 18: 564-570.
7. Ferrazzi E, Bozzo M, Rigano S, Bellotti M, Morabito A, Pardi G, Battaglia FC, Galan HL. Temporal sequence of abnormal Doppler changes in the peripheral and central circulatory systems of the severely growth-restricted fetus. Ultrasound Obstet Gynecol 2002; 19: 140-146.
8. Baschat AA, Gembruch U, Reiss I, Gortner L, Weiner CP, Harman CR. Relationship between arterial and venous Doppler and perinatal outcome in fetal growth restriction. Ultrasound Obstet Gynecol 2000; 16: 407-413.
9. Jones CT. Reprogramming of metabolic development by restriction of fetal growth. Biochem Soc Trans 1985; 13: 89-91.
10. Warshaw JB. Intrauterine growth retardation: adaptation or pathology. Pediatrics 1985; 51: 15-19.
11. Bernstein IM, Horbar JD, Badger GJ, Ohlsson A, Golan A. Morbidity and mortality among very low birth weight neonates with intrauterine growth restriction. Am J Obstet Gynecol 2000; 182: 198-206.
12. Karsdorp VHM, van Vugt JMG, van Geijn HP, Kostense PJ, Arduini D, Montenegro N, Todros T. Clinical significance of absent or reversed end diastolic velocity waveforms in umbilical artery. Lancet 1994; 344: 1664-1668.
13. Gortner L, Wauer RR, Stock GJ, Reiter HL, Reiss I, Jorch G, Hentschel R, Hieronimi G. Neonatal outcome in small for gestational age infants: Do they really better? J Perinat Med 1999; 27: 484-489.
14. Weiner CP, Williamson RA. Evaluation of severe growth retardation using cordocentesis - hematologic and metabolic alterations by etiology. Obstet Gynecol 1989; 73: 225-229.
15. Bilardo C, Nicolaides KH, Campbell S. Doppler measurements of fetal uteroplacental circulations: Relationship with umbilicla venous blood gases measured at cordocentesis. Am J Obstet Gynecol 1990; 162: 115-120.
16. Voßbeck S, Kraus de Camargo O, Grab D, Bode H, Pohland F. Neonatal and neurodevelopmental outcome in infants born before 30 weeks of gestation with absent or reversed end-diastolic flow velocities in the umbilical artery. Eur J Pediatr 2001; 160: 128-134.
17. Piper JM, Xenakis EM, McFarland M, Elliot BD, Berkus MD, Langer O. Do growth retarded premature infants have different rates of perinatal morbidity and mortality than appropriate for gestational grown premature infants? Obstet Gynecol 1996; 87: 169-174.
18. Procianoy RS, Garcia-Prats JA, Adams JM, Silvers A, Rudolph AJ. Hyaline membrane disease and intraventricular haemorrhage in small for gestational age infants. Arch Dis Child 1980; 55: 502-505.
19. Rizzo G, Capponi A, Chaoui R, Taddei F, Arduini D, Romanini C. Blood flow velocity waveform from peripheral pulmonary arteries in normally grown and growth-retarded fetuses. Ultrasound Obstet Gynecol 1996; 8: 87-92.
20. Malcom G, Ellwood D, Devonald K, Beilby R, Henderson-Smart D. Absent or reversed end diastolic flow velocity in the umbilical artery and necrotising enterocolitis. Arch Dis Child 1991; 66: 805-807.
21. Scherjon SA, Smolders-DeHaas H, Kok JH, Zondervan HA. The 'brain-sparing' effect: antenatal cerebral Doppler findings in relation to neurological outcome in very preterm infants. Am J Obstet Gynecol 1993; 169: 169-175.
22. Baschat AA, Gembruch U, Reiss I, Gortner L, Diedrich K. Demonstration of fetal coronary blood flow by Doppler ultrasound in relation to arterial and venous flow velocity waveform and perinatal outcome - the 'heart-sparing effect'. Ultrasound Obstet Gynecol 1997; 8: 82-86.
23. Chaoui R. The fetal 'heart-sparing effect' detected by the assessment of coronary blood flow: a further ominous sign of fetal compromise. Ultrasound Obstet Gynecol 1996; 7: 5-9.
24. Chaoui R. Coronary arteries in fetal life: physiology, malformations and the 'heart-sparing effect'. Acta Paediatr 2004; 93: 6-12.
25. Baschat AA, Reiss I, Gortner L. Absent umbilical artery end-diastolic velocity in growth-restricted fetuses: a risk factor for neonatal thrombocytopenia. Obstet Gynecol 2000; 96: 162-166.
26. Fong KW, Ohlsson A, Hannah ME. Prediction of perinatal outcome in fetuses suspected to have growth restriction: Doppler US study of fetal cerebral, renal and umbilical arteries. Radiology 1999; 213: 681-689.
27. Baschat AA, Reiss I, Gortner L. Brain sparing does not cause intraventricular hemorrhage. Am J Obstet Gynecol 2000; 182: (Suppl): 125.
28. Baschat AA, Gembruch U, Viscardi RM, Gortner L, Harman CR. Antenatal prediction of intraventricular hemorrhage in fetal growth restriction: what is the role of Doppler? Ultrasound Obstet Gynecol 2002; 19: 334-339.