Impaired energy metabolism after co-exposure to lead and ethanol

Basic and Clinical Pharmacology and Toxicology

Volumn 96, Issue 6, 2005, Pages 475-479

  Verma, Suresh Kumar ^a   Dua, Raina ^a   Gill, Kiran Dip ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALCOHOL; CYTOCHROME C OXIDASE; LEAD; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SUCCINATE DEHYDROGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BRAIN MITOCHONDRION; CELL ENERGY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENERGY METABOLISM; ENVIRONMENTAL EXPOSURE; MALE; METABOLIC DISORDER; MITOCHONDRIAL RESPIRATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN;

EID: 20644449260     PISSN: 17427835     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2005.pto_96611.x     Document Type: Article

References (28)

1. Awasthi, Y. C., T. F. Chuang, T. W. Keenan & F. L. Crane: Tightly bound cardiolipin in cytochrome oxidase. Biochem. Biophys. Acta. 1971, 226, 42-52.
2. Cezard C., C. Demarquilly, M. Boniface & J. M. Haguenoern: Influence of the degree of exposure on lead on relations between alcohol consumption and the biological indices of lead exposure: epidemiological study in a lead acid battery factory. Brit. J. Ind. Med. 1992, 49, 645-647.
3. Dresel, E. I. & J. F. Falk: Studies on the biosynthesis of blood pigment. Heme synthesis in hemolysed erythrocytes of chicken blood. Biochem. J. 1954, 56, 156-163.
4. 2+ ATPase activity and fluidity of synaptosomal membrane. Pharmacology & Toxicology. 1990, 67, 56-60.
5. Ercal, N., P. Treeratphan, T. C. Hammond, R. H. Matthews, N. Grannemann & D. Spitz: in vivo indices of oxidative stress in lead exposed C57b1/6 mice are reduced by treatment with meso-2,3-dimercaptosuccinic acid or N-acetylcysteine. Free Radic. Biol Med. 1996, 21, 865-869.
6. Erecinska, M. & D.F. Wilson: Regulation of cellular energy metabolism. J. Membr. Biol 1982, 70, 1-14.
7. Gulati, A., H. Chandishwari, K. Shankar, R. C. Srimal, K. N. Dhawan & K. P. Bhargawa: Effect of alcohol on the permeability of blood brain barrier. Pharmacol. Res. Commun. 1985, 17, 85-93.
8. Gupta, V. & K. D. Gill: Influence of ethanol on lead distribution and biochemical changes in rats exposed to lead. Alcohol 2000a, 20, 9-17.
9. Gupta, V. & K. D. Gill: Lead and ethanol coexposure: implications on the dopaminergic system and associated behavioral functions. Pharmacol. Biochem. Behav. 2000b, 66, 465-474.
10. Gupta, V. & K. D. Gill: Structural and functional alterations in the synaptic plasma membranes of rats exposed to lead and ethanol. J. Biochem. Mol. Biol. Biophys. 2002, 6, 29-36.
11. Holtzman, S., J. Nikkanen, G. Mellin & S. K. Tondon: Early effects of inorganic lead on immature rat brain mitochondrial respiration. Pediatric Res. 1976, 10, 70-75.
12. Jindal, V. & K. D. Gill: Ethanol potentiates lead-induced inhibition of rat brain antioxidant defense system. Pharmacology & Toxicology 1999, 85, 16-21.
13. Kadenbach, B.: Regulation of respiration and ATP synthesis in higher organism: hypothesis. J. Bioenerg. Biomembr. 1986, 18, 39-54.
14. King, T. E. & R. L. Howard: Preparation and properties of soluble NADH dehydrogenase from cardiac muscle. In: Methods in enzymology, Vol. 10. Oxidation and phosphorylation. Eds.: S. P. Colowick & N. O. Kaplan. Academic Press, N.Y., 1967, pp. 275-76.
15. King, T. S.: Preparation of succinate dehydrogenase and reconstitution of succinate oxidase. In: Methods in Enzymology. Vol. 10, Oxidation and phosphorylation. Eds.: S. P. Colowick & N. O. Kaplan. Academic Press, N.Y., 1967, pp. 322-325.
16. Lovtrup, S. & L. Svennerholm: Chemical properties of brain mitochondria. Exp. Cell. Res. 1963, 29, 298-313.
17. Lowry, O. H., N. J. Rosenbrough, A. L. Farr & R. J. Randall: Protein measurement with the folin phenol reagent. J. Biol. Chem. 1951, 193, 265-275.
18. Mylroie, A. A., H. Collins, C. Umbles & J. Kyle: Erythrocyte superoxide dismutase activity and other parameters of copper status in rats ingesting lead acetate. Toxicol. Appl. Phormacol. 1986, 82, 512-520.
19. Needleman, H. L., A. Schell, D. Bellinger, A. Leviton, & E. N. Allred: The long term effects of exposure to low doses of lead in childhood. An 11 years follow up report. New Engl. J. Med. 1990, 322, 83-88.
20. Ozawa, T: Mechanism of somatic mitochondrial DNA mutation associated with age and diseases. Biochim. Biophys. Acta 1995, 1271, 177-189.
21. Papa, S.: Mitochondrial oxidative phosphorylation changes in the life span. Molecular aspects and physiological implications. Biochim. Biophys. Acta 1996, 1276, 87-105.
22. 2 receptors in rat brain following ethanol withdrawal: A quantitative autoradiographic investigation. Alcohol 1992, 9, 355-362.
23. Slater, T. S.: Free-radical mechanism in tissue injury. Biochem. J. 1984, 222, 1-5.
24. Solliway, B. M, A. Schaffer, H. Pratt & S. Yannia: Effects of exposure to lead on selected biochemical and haematological variables. Pharmacology & Toxicology 1996, 78, 18-22.
25. Sotocassa, G. L., E. Bokuylenstiema, L. Ernster & A. Bergstrand: An electron transport system associated with the outer membrane of liver mitochondria. J. Cell Biol. 1967, 32, 415-438.
26. Strubelt, O.: Alcohol potentiation of liver injury. Fund. Appl. Toxicol. 1984, 4, 144-151.
27. Thayer, W. S. & H. Rottenberg: Comparative effects of chronic ethanol consumption on the properties of mitochondria from rat brain and liver. Alcohol. Clin. Exp. Res. 1992, 16, 1-4.
28. Todd, A. C., J. G. Wetmur, J. M. Moline, J. H. Godbold, S. M. Levin & P. J. Landrigan: Unrevealing the chronic toxicity of led: An essential priority for environmental health. Environ. Health Prospect. 1996, 104 (Suppl. 1), 141-146.