Comparison of darifenacin and oxybutynin in patients with overactive bladder: Assessment of ambulatory urodynamics and impact on salivary flow

European Urology

Volumn 48, Issue 1, 2005, Pages 102-109

  Chapple, C R ^a   Abrams, P ^b  

^a ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

^b SOUTHMEAD HOSPITAL   (United Kingdom)

Author keywords

Darifenacin; Heart rate; Overactive bladder; Oxybutynin; Salivary flow; Urodynamics

Indexed keywords

ANTIBIOTIC AGENT; DARIFENACIN; MUSCARINIC M3 RECEPTOR ANTAGONIST; OXYBUTYNIN;

ADULT; AGED; ARTICLE; ASTHENIA; CLINICAL TRIAL; COHORT ANALYSIS; CONFUSION; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG RELEASE; DYSPEPSIA; DYSPHAGIA; DYSURIA; EPISTAXIS; FEMALE; HEADACHE; HEART RATE; HUMAN; MAJOR CLINICAL STUDY; MALE; OVERACTIVE BLADDER; PARAMETER; PHARYNGITIS; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; SALIVATION; SOMNOLENCE; SORE THROAT; STATISTICAL SIGNIFICANCE; URINARY TRACT DISEASE; URODYNAMICS; VISION; VISUAL IMPAIRMENT; XEROPHTHALMIA; XEROSTOMIA;

ADOLESCENT; ADULT; AGED; ANTI-INFECTIVE AGENTS, URINARY; BENZOFURANS; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MANDELIC ACIDS; MIDDLE AGED; MONITORING, AMBULATORY; PYRROLIDINES; SALIVA; TREATMENT OUTCOME; URINARY INCONTINENCE; URODYNAMICS;

EID: 20644437758     PISSN: 03022838     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eururo.2005.04.018     Document Type: Article

References (19)

1. P. Abrams, L. Cardozo, M. Fall, D. Griffiths, P. Rosier, and U. Ulmsten The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society Neurourol Neurodyn 21 2002 167 178
2. G.A. Digesu, V. Khullar, L. Cardozo, and S. Salvatore Overactive bladder symptoms: do we need urodynamics? Neurourol Urodyn 22 2 2003 105 108
3. K-E. Andersson Antimuscarinics for the treatment of overactive bladder Lancet Neurol 3 2004 46 53
4. T. Yamanishi, C.R. Chapple, and R. Chess-Williams Which muscarinic receptor is important in the bladder? World J Urol 19 2001 299 306
5. 3 receptor subtype [abstract] Neurourol Urodyn 21 2002 A445
6. Task Force of the European Society of Cardiology and The North American Society of Pacing and Electrophysiology Heart rate variability: standards of measurement, physiological interpretation, and clinical use Eur Heart J 17 1996 354 381
7. D.J. Rosario, D.J. Smith, S.C. Radley, and C.R. Chapple Pharmacodynamics of anticholinergic agents measured by ambulatory urodynamic monitoring: a study of methodology Neurourol Urodyn 18 1999 223 234
8. 3 receptor selectivity Eur Urol Suppl 1 2002 23 28
9. 3 selective receptor antagonist for the treatment of overactive bladder, in healthy volunteers. BJU Int 2005; in press.
10. 3 selective antimuscarinic agent under investigation for the treatment of overactive bladder) J Urol 173 2005 493 498
11. K. Brown, and P. Hilton Ambulatory monitoring Int Urogynecol J 8 1997 369 376
12. K. Heslington, and P. Hilton Ambulatory monitoring and conventional cystometry in asymptomatic female volunteers Br J Obstet Gynaecol 103 1996 434 441
13. E.S.C. van Waalwijk van Doorn, A.W. Ambergen, and R.A. Janknegt Detrusor activity index: quantification of detrusor overactivity by ambulatory monitoring J Urol 157 2 1997 596 599
14. S.C. Radley, D.J. Rosario, C.R. Chapple, and A.G. Farkas Conventional and ambulatory urodynamic findings in women with symptoms suggestive of bladder overactivity J Urol 166 2001 2253 2258
15. A.J. Wein Pharmacological agents for the treatment of urinary incontinence due to overactive bladder Expert Opin Investig Drugs 10 1 2001 65 83
16. 3 receptors regulate exocrine secretion by mucous acini Am J Physiol 271 1996 C1963 C1972
17. 3 subtype Proc Natl Acad Sci USA 97 2000 9579 9584
18. 3 muscarinic receptor single- and double-knockout mice Mol Pharmacol 66 2 2004 260 267
19. J.G. Cunha-Vaz The blood-ocular barriers: past, present, and future Doc Ophthalmol 93 1997 149 157