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Volumn 25, Issue 4, 1997, Pages 1035-1037

Targeting the Achilles' heel of hepatitis C virus

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; PROTEIN KINASE INHIBITOR; SERINE PROTEINASE; VIRUS ENZYME; VIRUS PROTEIN;

EID: 20644432435     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510250441     Document Type: Note
Times cited : (5)

References (10)
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    • Hijikata, M.1    Mizushima, H.2    Akagi, T.3    Mori, S.4    Kakiuchi, N.5    Kato, N.6    Tanaka, T.7
  • 3
    • 0027414062 scopus 로고
    • Characterization of the hepatitis C virus-encoded serine proteinase: Determination of proteinase-dependent polyprotein cleavage sites
    • Grakoui A, McCourt DW, Wychowski C, Feinstone SM, Rice CM. Characterization of the hepatitis C virus-encoded serine proteinase: Determination of proteinase-dependent polyprotein cleavage sites. J Virol 1993;67:2832-2843.
    • (1993) J Virol , vol.67 , pp. 2832-2843
    • Grakoui, A.1    McCourt, D.W.2    Wychowski, C.3    Feinstone, S.M.4    Rice, C.M.5
  • 4
    • 0027287798 scopus 로고
    • Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions
    • Bartenschlager R, Ahlborn-Laake L, Mous J, Jacobsen H. Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions. J Virol 1993;67:3835-3844.
    • (1993) J Virol , vol.67 , pp. 3835-3844
    • Bartenschlager, R.1    Ahlborn-Laake, L.2    Mous, J.3    Jacobsen, H.4
  • 5
    • 0029074519 scopus 로고
    • A central region in the hepatitis C virus NS4A protein allows formation of an active NS3-NS4A serine proteinase complex in vivo and in vitro
    • Lin C, Thomson JA, Rice CM. A central region in the hepatitis C virus NS4A protein allows formation of an active NS3-NS4A serine proteinase complex in vivo and in vitro. J Virol 1995;69:4373-4380.
    • (1995) J Virol , vol.69 , pp. 4373-4380
    • Lin, C.1    Thomson, J.A.2    Rice, C.M.3
  • 6
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    • Structure-based inhibitors of HIV-1 protease
    • Wlodawer A, Erickson JW. Structure-based inhibitors of HIV-1 protease. Ann Rev Biochem 1993;62:543-585.
    • (1993) Ann Rev Biochem , vol.62 , pp. 543-585
    • Wlodawer, A.1    Erickson, J.W.2
  • 7
    • 0030592514 scopus 로고    scopus 로고
    • The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site
    • Love RA, Parge HE, Wickersham JA, Hostomsky Z, Habuka N, Moomraw EW, Adachi T, et al. The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site. Cell 1996;87:331-342.
    • (1996) Cell , vol.87 , pp. 331-342
    • Love, R.A.1    Parge, H.E.2    Wickersham, J.A.3    Hostomsky, Z.4    Habuka, N.5    Moomraw, E.W.6    Adachi, T.7
  • 8
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    • Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide
    • Kim JL, Morgenstern KA, Lin C, Fox T, Dwyer MD, Landro JA, Chambers SP, et al. Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide. Cell 1996;87:343-355.
    • (1996) Cell , vol.87 , pp. 343-355
    • Kim, J.L.1    Morgenstern, K.A.2    Lin, C.3    Fox, T.4    Dwyer, M.D.5    Landro, J.A.6    Chambers, S.P.7
  • 9
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.