Isoenzyme analysis for cell line authentication

BioPharm International

Volumn 18, Issue 6, 2005, Pages

  Nims, Raymond W ^a   Herbstritt, Christopher J ^a  

^a BioReliance   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTATE AMINOTRANSFERASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; LACTATE DEHYDROGENASE; MALATE DEHYDROGENASE; NUCLEOSIDE PHOSPHORYLASE; PEPTIDASE;

BIOMEDICINE; CELL CULTURE; CELL LINE; CELL POPULATION; CELL PROLIFERATION; CERCOPITHECUS; CHINESE HAMSTER; CHO CELL; COW; DNA FINGERPRINTING; ELECTROPHORESIS; HUMAN; ISOENZYME ANALYSIS; KARYOTYPING; MICROBIAL CONTAMINATION; MONKEY; NONHUMAN; REVIEW;

EID: 20544473797     PISSN: 1542166X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (9)

1. Markovic O, Markovic N. Cell cross-contamination in cell cultures: The silent and neglected danger. In Vitro Cell. Dev. Biol. 1998; 34:1-8.
2. Hay RJ. The seed stock concept and quality control for cell lines. Anal. Biochem. 1988; 171:225-237.
3. Steube KG, et al. Isoenzyme analysis as a rapid method for the examination of the species identity of cell cultures. In Vitro Cell. Dev. Biol. 1995; 31:115-119.
4. CBER. Points to Consider in the Characterization of Cell Lines Used to Produce Biologicals. Bethesda, MD: Office of Biologies Research and Review, FDA; 1993.
5. ICH. Guideline on Quality of Biotechnological/Biological Products: Derivation and Characterization of Cell Substrates Used in the Production of Biotechnological/Biological Products. Q5D. Geneva, Switzerland: International Conference on Harmonization; 1997.
6. Innovative Chemistry, Inc. The AuthentiKit System. Handbook for Cell Authentication and Identification. 2nd ed., Marshfield, MA; 1988.
7. Halton DM, et al. Cell culture quality control by rapid isoenzymatic characterization. In Vitro 1983; 19:16-24.
8. Nims RW, et al. Sensitivity of isoenzyme analysis for the detection of interspecies cell line cross-contamination. in Vitro Cell. Dev. Biol. 1998; 34:35-39.
9. Hay RJ, et al. Reply to "Cells, lines, and DNA fingerprinting" In Vitro Cell. Dev. Biol. 1992; 28A:593-594.