Th2-type immune response observed in healthy individuals to sonicate antigen prepared from the most prevalent Mycobacterium tuberculosis strain with single copy of IS6110

FEMS Immunology and Medical Microbiology

Volumn 45, Issue 1, 2005, Pages 95-102

  Rajavelu, Priya ^a   Das, Sulochana D ^a  

^a NATIONAL INSTITUTE FOR RESEARCH IN TUBERCULOSIS   (India)

Author keywords

IS6110; Mycobacterium tuberculosis; Prevalent strains; Sonicate antigens; Th2 response

Indexed keywords

CD4 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INTERLEUKIN 12; INTERLEUKIN 4; MYCOBACTERIUM ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BACTERIAL STRAIN; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; MYCOBACTERIUM TUBERCULOSIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN PURIFICATION; T LYMPHOCYTE; TH1 CELL; TH2 CELL; ULTRASOUND;

ADULT; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; CYTOKINES; DNA TRANSPOSABLE ELEMENTS; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-4; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBSETS; LYMPHOCYTES; MACROPHAGES; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; SONICATION; TH2 CELLS; TUBERCULIN; TUBERCULOSIS, PULMONARY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 20544468352     PISSN: 09288244     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.femsim.2005.02.011     Document Type: Article

References (29)

1. R. Hernandez-Pando, H. Orozcoe, A. Sampieri, L. Pavon, C. Velasquillo, J. Larriva-Sahd, J.M. Alcocer, and M.V. Madrid Correlation between kinetics of Th1, Th2 cells and pathology in a murine model of experimental pulmonary tuberculosis Immunology 89 1996 26 33
2. C.A. Power, G. Ivei, and P.A. Bretscher Mycobacterial dose defines the Th1/Th2 nature of the immune response independently of whether immunization is administered by intravenous, subcutaneous, or intradermal route Infect. Immun. 66 1998 5743 5750
3. S. Sreevatsan, X. Pan, K.E. Stockbauer, N.D. Connell, B.N. Kreiswirth, T.S. Whittam, and J.M. Musser Restricted structural gene polymorphism in the Mycobacterium tuberculosis complex indicates evolutionary recent global dissemination Proc. Natl. Acad. Sci. USA 94 1997 9869 9874
4. Y. Yuan, D.C. Crane, J.M. Musser, S. Sreevatsan, and CE. Barry III MMAS-1, the branch point between cis- and trans-cyclopropane-containing oxygenated mycolates in Mycobacterium tuberculosis J. Biol. Chem. 272 1997 10041 10049
5. C. Manca, L. Tsenova, A. Bergtold, S. Freeman, M. Tovey, J.M. Musser, C.E. Barry III, V.H. Freedman, and G. Kapplan Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-a/b Proc. Natl. Acad. Sci. USA 98 2001 5752 5757
6. C. Manca, L. Tsenova, C.E. Barry III, A. Bergtold, S. Freeman, P.A.J. Haslett, J.M. Musser, V.H. Freedman, and G. Kapplan Mycobacterium tuberculosis CDC1551 induces a more vigorous host response in vivo and in vitro, but is not more virulent than other clinical isolates J. Immunol. 162 1999 6740 6746
7. M.K. Sharma, A. Al-Azem, J. Wolfe, E. Hershfield, and A Kabani Identification of a predominant isolate of Mycobacterium tuberculosis using molecular and clinical epidemiology tolls and in vitro cytokine responses BMC Infect. Dis. 3:3 2003
8. S.E. Valway, M.P.C. Sanchez, T.M. Shinnick, I. Orme, T. Agerton, D. Hoy, J.S. Jones, H. Westmoreland, and I.M. Onorato An outbreak involving extensive transmission of a virulent strain Mycobacterium tuberculosis New Engl. J. Med. 338 1998 633 639
9. S. Bhattacharyya, R. Singla, A.B. Dey, and H.K. Prasad Dichotomy of cytokine profiles in patients and high risk healthy subjects exposed to tuberculosis Infect. Immun. 67 1999 5597 5603
10. S. Das, C.N. Paramasivan, D.B. Lowrie, R. Prabhakar, and P.R. Narayanan IS6110 restriction fragment length polymorphism typing of clinical isolates of Mycobacterium tuberculosis from patients with pulmonary tuberculosis in Madras, South India Tubercle Lung Dis. 76 1995 550 554
11. S.D. Das, S. Narayanan, L. Hari, S.L. Hoti, R.K. Thangathurai, N. Charles, K. Jaggarajamma, and P.R. Narayanan Differentiation of highly prevalent IS6110 single-copy strains of Mycobacterium tuberculosis from a rural community in South India with an ongoing DOTS programme Infect. Genet. Evol. 5 2005 67 77
12. S.L. Sampson, R.M. Warren, M. Richardson, G.D. Van der spuy, and P.D. Van Helden Disruption of coding regions by IS6110 insertion in Mycobacterium tuberculosis Tubercle Lung Dis. 79 1999 349 359
13. P.F. Barnes, and M. Donald Cave Molecular epidemiology of tuberculosis New Engl. J. Med. 394 2003 1149 1156
14. P. Rajavelu, and S. Das Cell-mediated immune responses of healthy laboratory volunteer to sonicate antigens prepared from the most prevalent strains of Mycobacterium tuberculosis from South India harboring a single copy of IS6110 Clin. Diagn. Lab. Immunol. 10 2003 1149 1152
15. S. Narayanan, S.D. Das, R. Garg, L. Hari, V.B. Rao, T.R. Frieden, and P.R. Narayanan Molecular epidemiology of tuberculosis in a rural area of high prevalence in South India: implications of disease control and prevention J. Clin. Microbiol. 40 2002 4785 4788
16. T. Jung, U. Schauer, C. Heusser, C. Neumann, and C. Rieger Detection of intracellular cytokines by flowcytometry J. Immunol. Meth. 159 1993 197 207
17. S.D. Das, P.R. Narayanan, C. Kolappan, and M.J. Colston The cytokine response to Bacille Camette Guerin vaccination in South India Int. J. Tuberc. Lung Dis. 10 1998 836 843
18. V. Mehra, J. Gong, D. Iyer, Y.G. Lin, C.T. Boylen, B.R. Bloom, and P.F. Barnes Immune response to recombinant mycobacterial proteins in patients with tuberculosis infection and disease J. Infect. Dis. 174 1996 431 434
19. K.S. Stephan, M. Torres, E. Sada, C. Carranza, E. Ramos, M. Tary-Lehmann, R.S. Wallis, W. Sierra, and E.A. Rich Enhanced responses to Mycobacterium tuberculosis antigens by human alveolar lymphocytes during active pulmonary tuberculosis J. Infect. Dis. 178 1998 1434 1445
20. S.M. Siddiqui, I.M. Orme, and R.K. Saxena Efficacy of culture filtrate protein preparations from Indian isolates of Mycobacterium tuberculosis to activate T cells derived from healthy donors Int. J. Tuberc. Lung Dis. 4 10 2000 980 987
21. P.F. Barnes, and R.L. Modlin Human cellular immune responses to Mycobacterium tuberculosis Curr. Top. Microbiol. Immunol. 215 1996 197 219
22. l.J. Cadrane, C. Philippe, J. Perez, B. Milleron, G. Akoun, R. Ardaillou, and L. Baud In vitro production of tumor necrosis factor and prostaglandin E2 by peripheral blood mononuclear cells from tuberculosis patients Clin. Exp. Immunol. 81 1990 319 324
23. P. Delobel, P. Launois, F. Djossou, D. Sainte-Marie, and R. Pradinaud American cutaneous leishmaniasis, lepromatous leprosy, and pulmonary tuberculosis coinfection with downregulation of the T-helper 1 cell response Clin. Infect. Dis. 37 2003 628 633
24. P. Salgame, J. Abrams, C. Clayberger, H. Goldstein, J. Convit, R.L. Modlin, and B.R. Bloom Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones Science 254 1991 279 281
25. J.J. Ellner Regulation of the human immune response during tuberculosis J. Lab. Clin. Med. 130 1997 469 475
26. X. Zhang, T. Brunner, L. Carter, R.W. Dutton, P. Rogers, L. Bradley, T. Sato, J.C. Reed, D. Green, and S.L. Swain Unequal death in T helper cell 1 (Th1) and Th2 effectors: Th1 but not Th2 effectors undergo rapid Fas/FasL-mediated apoptosis J. Exp. Med. 185 1997 1837 1849
27. M.L. Wilsher, C. Hagan, R. Prestidge, A.U. Wells, and G. Murison Human in vitro immune responses to Mycobacterium tuberculosis Tubercle Lung Dis. 76 1999 371 377
28. Y. Lin, M. Zhang, F.M. Hoffman, J. Gong, and P.F. Barnes Absence of a prominent Th2 cytokine response in human tuberculosis Infect. Immun. 64 1996 1351 1356
29. K.V. Jalapathy, C. Prabha, and S.D. Das Correlates of protective immune response in tuberculous pleuritis FEMS Immunol. Med. Microbiol. 40 2004 139 145