Transcriptional activity of the 5′ upstream region of the porcine glycoprotein hormone α subunit gene

Journal of Reproduction and Development

Volumn 51, Issue 1, 2005, Pages 117-121

  Aikawa, Satoko ^a   Susa, Takao ^a   Sato, Takanobu ^a   Kitahara, Kousuke ^a   Kato, Takako ^a   Kato, Yukio ^a  

^a MEIJI UNIVERSITY   (Japan)

Author keywords

Glycoprotein hormone; Pig; Pituitary; Ptx1; Transcription

Indexed keywords

CRICETULUS GRISEUS; MUS MUSCULUS; SUIDAE; SUS SCROFA;

COMPLEMENTARY DNA; DNA BINDING PROTEIN; GLYCOPROTEIN; HOMEOBOX PROTEIN PITX1; HOMEODOMAIN PROTEIN; PAIRED BOX TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR;

ALPHA CHAIN; ANIMAL; ARTICLE; BINDING SITE; BIOSYNTHESIS; CHO CELL; GENE EXPRESSION REGULATION; GENE VECTOR; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; HAMSTER; HYPOPHYSIS; METABOLISM; PROMOTER REGION; REPORTER GENE; SWINE; TIME;

ANIMALS; BINDING SITES; CHO CELLS; CRICETINAE; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GENES, REPORTER; GENETIC VECTORS; GLYCOPROTEIN HORMONES, ALPHA SUBUNIT; GLYCOPROTEINS; HOMEODOMAIN PROTEINS; PAIRED BOX TRANSCRIPTION FACTORS; PITUITARY GLAND; PROMOTER REGIONS (GENETICS); SWINE; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 20544452842     PISSN: 09168818     EISSN: None     Source Type: Journal    
DOI: 10.1262/jrd.51.117     Document Type: Article

References (14)

1. Pierce JG, Parsons TF. Glycoprotein hormones: structure and function. Ann Rev Biochem 1981; 50: 465-495.
2. Maurer RA, Kim KE, Schoderbek WE, Roberson MS, Glenn DJ. Regulation of glycoprotein hormone alpha-subunit gene expression. Recent Prog Horm Res 1999; 54: 455-484.
3. Bokar JA, Keri RA, Famerie TA, Fenstermaker RA, Andersen B, Hamernik DL, Yun J, Wagner T, Nilson JH. Expression of the glycoprotein hormone α-subunit in the placenta requires a functional cyclic AMP response element, whereas a different cis-acting element mediates pituitary-specific expression. Mol Cell Biol 1989; 9: 5113-5122.
4. Kennedy GC, Andersen B, Nilson JH. The human a subunit glycoprotein hormone gene utilizes a unique CCAAT binding factor. J Biol Chem 1990; 265: 6279-6285.
5. Roberson MS, Schoderbek WE, Tremml G, Maurer RA. Activation of the glycoprotein hormone α-subunit promoter by a LIM-homeodomain transcription factor. Mol Cell Biol 1994; 14: 2985-2993.
6. Barnhart KM, Mellon PL. The orphan nuclear receptor, steroidogenic factor-1, regulates the glycoprotein hormone α-subunit gene in pituitary gonadotropes. Mol Endocrinol 1994; 8: 878-885.
7. Kato Y, Ezashi T, Kato T. The gene for the common α subunit of porcine glycoprotein hormone. J Mol Endocrinol 1991; 7: 27-34.
8. Kato Y, Ezashi T, Kato T. Restriction fragment length polymorphism of the porcine pituitary glycoprotein common α subunit gene. J Reprod Dev 1992; 38: 45-47.
9. Tremblay JJ, Lanctôt, Drouin J. The pan-pituitary activator of transcription, Ptx1 (pituitary homeobox 1), acts in synergy with SF-1 and Pit-1 and is an upstream regulator of the Lim-homeodomain gene Lim3/Lhx3. Mol Endocrinol 1998; 12: 428-441.
10. Alarid ET, Windle JJ, Whyte DB, Mellon PL. Immortalization of pituitary cells at discrete stages of development by directed oncogenesis in transgenic mice. Development 1996; 122: 3319-3329.
11. Lamonerie T, Tremblay JJ, Lanctôt, Therrien M, Gauthier Y, Drouin J. Ptx1, a bicoid-related homeo box transcription factor involved in transcription of the pro-opiomelanocortin gene. Genes Dev 1996; 10: 1284-1295.
12. Aylwin SJ, Burrin JM. The role of transcription factors in the pituitary expression of the glycoprotein hormone alpha-subunit gene. J Mol Endocrinol 1995; 15: 221-231.
13. Bdall SK, Sarapura VD, Wood WM, Ridgway EC, Camper SA. Cell-specific expression of the mouse glycoprotein hormone α-subunit gene requires multiple interacting DNA elements in transgenic mice and cultured cells. Mol Endocrinol 1998; 12: 622-623.
14. Horn F, Windle J, Barnhart KM, Mellon PL. Tissue-specific gene expression in the pituitary: the glycoprotein hormone α-subunit gene is regulated by a gonadotrope-specific protein. Mol Cell Biol 1992; 12: 2143-2153.