Pontine maps linking somatosensory and cerebellar cortices are in register with climbing fiber somatotopy

Journal of Neuroscience

Volumn 25, Issue 24, 2005, Pages 5680-5690

  Odeh, Francis ^a   Ackerley, Rochelle ^b   Bjaalie, Jan G ^a   Apps, Richard ^b  

^a UNIVERSITY OF OSLO   (Norway)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

3 D reconstruction; Cerebellum; Cerebral cortex; Inferior olive; Pontine nuclei; Primary somatosensory cortex; Somatotopy

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN MAPPING; BRAIN NUCLEUS; BRAIN REGION; CELL LABELING; CEREBELLUM CORTEX; CLIMBING FIBER; FACE; FEMALE; FORELIMB; HINDLIMB; INFERIOR OLIVE; MALE; MOSSY FIBER; NEUROANATOMY; NONHUMAN; PONS; PRIORITY JOURNAL; RAT; SOMATOSENSORY CORTEX; THREE DIMENSIONAL IMAGING; TOPOGRAPHY;

AFFERENT PATHWAYS; ANIMALS; BRAIN MAPPING; CEREBELLAR CORTEX; ELECTRIC STIMULATION; FEMALE; MODELS, ANIMAL; NERVE FIBERS; PONS; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; SOMATOSENSORY CORTEX; STEREOTAXIC TECHNIQUES;

EID: 20544448296     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0558-05.2005     Document Type: Article

References (47)

1. Apps R (1990) Columnar organisation of the inferior olive projection to the posterior lobe of the rat cerebellum. J Comp Neurol 302:236-254.
2. Apps R, Garwicz M (2005) Anatomical and physiological foundations of cerebellar information processing. Nat Rev Neurosci 6:297-311.
3. Ashburner J, Friston KJ (1999) Spatial normalization. In: Brain warping (Toga AW, ed), pp 27-44. San Diego: Academic.
4. Atkins MJ, Apps R (1997) Somatotopical organisation within the climbing fibre projection to the paramedian lobule and copula pyramidis of the rat cerebellum. J Comp Neurol 389:249-263.
5. Bjaalie JG, Brodal P (1997) Cat pontocerebellar network: numerical capacity and axonal collateral branching of neurones in the pontine nuclei projecting to individual parafloccular folia. Neurosci Res 27:199-210.
6. Bower JM, Kassel J (1990) Variability in tactile projection patterns to cerebellar folia crus IIA of the Norway rat. J Comp Neurol 302:768-778.
7. Bower JM, Beermann DH, Gibson JM, Shambes GM, Welker W (1981) Principles of organization of a cerebro-cerebellar circuit. Micromapping the projections from cerebral (SI) to cerebellar (granule cell layer) tactile areas of rats. Brain Behav Evol 18:1-18.
8. Brevik A, Leergaard TB, Svanevik M, Bjaalie JG (2001) Three-dimensional computerised atlas of the rat brain stem precerebellar system: approaches for mapping, visualization, and comparison of spatial distribution data. Anat Embryol (Berl) 204:319-332.
9. Brodal P, Bjaalie JG (1992) Organization of the pontine nuclei. Neurosci Res 13:83-118.
10. Brodal P, Bjaalie JG (1997) Salient anatomic features of the cortico-pontocerebellar pathway. Prog Brain Res 114:227-249.
11. Brown IE, Bower JM (2001) Congruence of mossy fiber and climbing fiber tactile projections in the lateral hemispheres of the rat cerebellum. J Comp Neurol 429:59-70.
12. Chapin JK, Lin CS (1990) The somatic sensory cortex of the rat. In: The cerebral cortex of the rat (Kolb B, Tees RC, eds), pp 341-380. Cambridge, MA: MIT.
13. Eccles JC, Provini L, Strata P, Taborikova H (1968) Analysis of electrical potentials evoked in the cerebellar anterior lobe by stimulation of hindlimb and forelimb nerves. Exp Brain Res 6:171-194.
14. Ekerot CF, Larson B (1980) Termination in overlapping sagittal zones in cerebellar anterior lobe of mossy and climbing fiber paths activated from dorsal funiculus. Exp Brain Res 38:163-172.
15. Eycken A, Bjaalie JG, Volny-Luraghi A, De Schutter E (2000) Electrophysiological study of the rat pontine nuclei. Eur J Neurosci Abstr 11:189.09.
16. Garwicz M, Jorntell H, Ekerot CF (1998) Cutaneous receptive fields and topography of mossy fibres and climbing fibres projecting to cat cerebellar C3 zone. J Physiol (Lond) 512:277-293.
17. 1 zone in lobulus simplex and paramedian lobule of the rat cerebellar cortex. Cerebellum 1:185-199.
18. Hollander H, Brodal P, Walberg F (1968) Electronmicroscopic observations on the structure of the pontine nuclei and the mode of termination of the corticopontine fibres. An experimental study in the cat. Exp Brain Res 7:95-110.
19. King VM, Armstrong DM, Apps R, Trott JR (1998) Numerical aspects of pontine, lateral reticular, and inferior olivary projections to two paravermal cortical zones of the cat cerebellum. J Comp Neurol 390:537-551.
20. Leergaard TB (2003) Clustered and laminar topographic patterns in rat cerebro-pontine pathways. Anat Embryol (Berl) 206:149-162.
21. Leergaard TB, Lakke EA, Bjaalie JG (1995) Topographical organization in the early postnatal corticopontine projection: a carbocyanine dye and 3-D computer reconstruction study in the rat. J Comp Neurol 361:77-94.
22. Leergaard TB, Lyngstad KA, Thompson JH, Taeymans S, Vos BP, De Schutter E, Bower JM, Bjaalie JG (2000a) Rat somatosensory cerebropontocerebellar pathways: spatial relationships of the somatotopic map of the primary somatosensory cortex are preserved in a three-dimensional clustered pontine map. J Comp Neurol 422:246-266.
23. Leergaard TB, Alloway KD, Mutic JJ, Bjaalie JG (2000b) Three-dimensional topography of corticopontine projections from rat barrel cortex: correlations with corticostriatal organization. J Neurosci 20:8474-8484.
24. Lillehaug S, Leergaard TB, De Schutter E, Bower JM, Bjaalie JG (2004) Ponto-cerebellar projections to electrophysiologically defined patches in the granule cell layer of rat Crus IIa. FENS Abstr 2:A129.8.
25. Mihailoff GA (1983) Intra- and interhemispheric collateral branching in the rat pontocerebellar system, a fluorescence double-label study. Neuroscience 10:141-160.
26. Mihailoff GA, McArdle CB (1981) The cytoarchitecture, cytology, and synaptic organization of the basilar pontine nuclei in the rat. II. Electron microscopic studies. J Comp Neurol 195:203-219.
27. Mihailoff GA, McArdle CB, Adams CE (1981) The cytoarchitecture, cytology, and synaptic organization of the basilar pontine nuclei in the rat. I. Nissl and Golgi studies. J Comp Neurol 195:181-201.
28. Mihailoff GA, Lee H, Watt CB, Yates R (1985) Projections to the basilar pontine nuclei from face sensory and motor regions of the cerebral cortex in the rat. J Comp Neurol 237:251-263.
29. Morissette J, Bower JM (1996) Contribution of somatosensory cortex to responses in the rat cerebellar granule cell layer following peripheral tactile stimulation. Exp Brain Res 109:240-250.
30. Panto MR, Cicirata F, Angaut P, Parenti R, Serapide F (1995) The projection from the primary motor and somatic sensory cortex to the basilar pontine nuclei. A detailed electrophysiological and anatomical study in the rat. J Hirnforsch 36:7-19.
31. Pardoe J, Apps R (2002) Structure-function relations of two somatotopically corresponding regions of the rat cerebellar cortex: olivo-corticonuclear connections. Cerebellum 1:165-184.
32. Pardoe J, Edgley SA, Drew T, Apps R (2004) Changes in excitability of ascending and descending inputs to cerebellar climbing fibers during locomotion. J Neurosci 24:2656-2666.
33. Rajan R, Cerminara NL, Rawson JA (2000) Response properties of pontine projections to the cerebellum in the rat. Soc Neurosci Abstr 26:742.8.
34. Schmahmann JD, Pandya DN (1997) The cerebrocerebellar system. Int Rev Neurobiol 41:31-60.
35. Schwarz C, Mock M (2001) Spatial arrangement of cerebro-pontine terminals. J Comp Neurol 435:418-432.
36. Schwarz C, Thier P (1995) Modular organization of the pontine nuclei: dendritic fields of identified pontine projection neurons in the rat respect the borders of cortical afferent fields. J Neurosci 15:3475-3489.
37. Schwarz C, Thier P (1999) Binding of signals relevant for action: towards a hypothesis of the functional role of the pontine nuclei. Trends Neurosci 22:443-451.
38. Shambes GM, Gibson JM, Welker W (1978) Fractured somatotopy in granule cell tactile areas of rat cerebellar hemispheres revealed by micromapping. Brain Behav Evol 15:94-140.
39. Shinoda Y, Sugiuchi Y, Futami T, Izawa R (1992) Axon collaterals of mossy fibers from the pontine nucleus in the cerebellar dentate nucleus. J Neurophysiol 67:547-560.
40. Teune TM, van der Burg J, De Zeeuw CI, Voogd J, Ruigrok TJ (1998) Single Purkinje cell can innervate multiple classes of projection neurons in the cerebellar nuclei of the rat: a light microscopic and ultrastructural triple-tracer study in the rat. J Comp Neurol 392:164-178.
41. Voogd J, Glickstein M (1998) The anatomy of the cerebellum. Trends Neurosci 21:370-375.
42. Voogd J, Pardoe J, Ruigrok TJ, Apps R (2003) The distribution of climbing and mossy fiber collateral branches from the copula pyramidis and the paramedian lobule: congruence of climbing fiber cortical zones and the pattern of zebrin banding within the rat cerebellum. J Neurosci 23:4645-4656.
43. Welker C (1971) Microelectrode delineation of fine grain somatotopic organization of (SmI) cerebral neocortex in albino rat. Brain Res 26:259-275.
44. Welker W (1987) Spatial organization of somatosensory projections to granule cell cerebellar cortex: functional and connectional implications of fractured somatotopy (summary of Wisconsin studies). In: New concepts in cerebellar neurobiology (King JS, ed), pp 239-280. New York: Liss.
45. Wiesendanger R, Wiesendanger M (1982) The corticopontine system in the rat. II. The projection pattern. J Comp Neurol 208:227-238.
46. Woolsey CN (1958) Organization of somatic sensory and motor areas of the cerebral cortex. In: Biological and biochemical bases of behaviour (Harlow HF, Woolsey CN, eds), pp 63-81. Madison, WI: University of Wisconsin.
47. Woolston DC, Kassel J, Gibson JM (1981) Trigeminocerebellar mossy fiber branching to granule cell layer patches in the rat cerebellum. Brain Res 209:255-269.