Solubilization of oleanolic acid and ursolic acid by cosolvency

Archives of Pharmacal Research

Volumn 20, Issue 3, 1997, Pages 269-274

  Jin, In Jung ^a   Ko, Young Ill ^a   Kim, Young Mi ^a   Han, Suk Kyu ^a  

^a Pusan National University   (South Korea)

Author keywords

Oleanolic acid; Solubility; Solubility parameter; Tetramethylurea; Ursolic acid

Indexed keywords

EID: 20544445448     PISSN: 02536269     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02976156     Document Type: Article

References (12)

1. Altwood, D. and Florence, A. T., Surfactant Systems, Chapman and Hall, New York, 1983
2. Bailey, Jr. F. D. and Koleske, J. V., Configuration and hydrodynamic properties of the polyoxyethylene chain in solution, in nonionic surfactants (Schick, M. J. ed.), Marcel Dekker, p. 794, 1967
3. Banker, G. S and Rhodes. C. T., Modern Pharmaceutics, Marcel Dekker, New York, p.19, 1979
4. Hildebrand, J. H., Prausnitz, J. H. and Scott, R. L., Regular and Related Solutions, Van Nostrand Reinhold, New York, 1970
5. Lee, H. Y., Chung, H. Y., Kim, K. H., Lee, J. J., and Kim, K. W., Induction of differentiation in the cultured F9 teratocarcinoma stem cells by triterpene acids, Journal of Cancer Research and Clinical Oncology, Vol. 120, p.513-518, 1994
6. Lee, H. Y. and Kim, K. W., Molecular analysis of the differentiation factor in the F9 teratocarcinoma cells, Mol. Cells, Vol. 24, p.572-577, 1991
7. Martin, A., Swarbrick, J., and Cammarata, A., Physical Pharmacy, Lea and Fabiger, Philadelphia, 1983
8. Sohn, K. H., Lee, O. H., Lee, Y. N., Chung, H. Y., Lee, J. J., and Kim, K. W., Anti-angiogenic activity of ursolic acid, Yakhak Hoeji, Vol. 5, p. 532-537, 1993
9. Yalkowsky, S. H., Techniques of Solubilization of Drugs, Marcel Dekker, New York, 1981
10. Fedors, R. F., A method for estimating both the solubility parameters and molar volumes of liquids, Polymer Eng. Sci., Vol. 14, p. 147-154, 1974
11. Luthringhans and Dirksen, H. W., Tetramethylurea as a solvent and reagent, Angew. Chem. Internat. Edit., Vol. 3, p. 260-269, 1964
12. Windholz, M., The Merk Index (10th ed.), Merck & Co., Rahway, N. J., U.S.A. p.9053, 1983