High performance liquid chromatographic assay of a new fluoroquinolone, LB20304, in the plasma of rats and dogs

Archives of Pharmacal Research

Volumn 19, Issue 6, 1996, Pages 554-558

  Seo, Mi Kyeong ^a   Jeong, Yi Na ^a   Kim, Hoon Joo ^a   Kim, In Chull ^a   Lee, Yong Hee ^a  

^a LG Chemical Ltd   (South Korea)

Author keywords

Fluoroquinolone; HPLC assay; LB20304; Plasma

Indexed keywords

EID: 20544438609     PISSN: 02536269     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02986027     Document Type: Article

References (4)

1. Kim, M. Y., Oh, J. I., Paek, K. S., Hong, C. Y., Kim, I. C. and Kwak, J. H., In vitro activities of LB20304, a new fluoroquinolone. Arch. Pharm. Res., 19, 52-59 (1996).
2. Marutani, K., Matsumoto, M., Otabe, Y., Nagamuta, K., Tanaka, K., Miyoshi, A., Hasegawa, T., Nagano, H., Matsubara, S. and Kamode, R., Reduced phototoxicity of a fluoroquinolone antibacterial agent with a methoxy group at the 8 position in mice irradiated with long-wavelength UV light. Antimicrob. Agents Chemother., 37, 2217-2223 (1993).
3. Seo, M. K., Lee, S. H., Choi, Y. J., Jeong, Y. N., Lee, S. H., Kim, I. C. and Lee, Y. H., Pharmacokinetics of LB20304, a new fluoroquinolone, in rats and dogs. Arch. Pharm. Res., in press (1996).
4. Shah, V. P., Midha, K. L., Dighe, S., McGilveray, I. J., Skelly, J. P., Yacobi, A., Layloff, T., Viswanathan, C. T., Cook, C.E., McDowall, R.D., Pittman, K. A. and Spector, S., Analytical methods validation: bioavailability, bioequivalence and pharmacokinetic studies. Pharm. Res., 9, 588-592 (1992).