Effect of pEgr-TNFα gene radiotherapy on mice melanoma

Melanoma Research

Volumn 15, Issue 3, 2005, Pages 185-190

  Wu, Congmei ^a   Li, Xiuyi ^b   Tian, Mei ^b  

^a SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

^b JILIN UNIVERSITY   (China)

Author keywords

Egr 1; Melanoma; Radiation; Tumour necrosis factor

Indexed keywords

EARLY GROWTH RESPONSE FACTOR 1; MESSENGER RNA; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CANCER RADIOTHERAPY; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GENE CONSTRUCT; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; GENETIC TRANSFECTION; IONIZING RADIATION; MELANOMA; MELANOMA B16; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; RADIATION EXPOSURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR GROWTH; ANIMAL; BLOOD; C57BL MOUSE; CANCER TRANSPLANTATION; COMPARATIVE STUDY; DISEASE MODEL; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL MELANOMA; GENETICS; METABOLISM; MULTIMODALITY CANCER THERAPY; SKIN TUMOR; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; COMBINED MODALITY THERAPY; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE THERAPY; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NEOPLASM TRANSPLANTATION; PLASMIDS; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SKIN NEOPLASMS; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 20544434074     PISSN: 09608931     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008390-200506000-00007     Document Type: Article

References (20)

1. Datta R, Rubin E, Sukhatme V, Qureshi S, Hallahan D, Weichselbaum RR, et al. Ionizing radiation activates transcription of the EGR1 gene via CArG elements. Proc Natl Acad Sci USA 1992; 89:10 149-10 153.
2. Weichselbaum RR, Hallahan DE, Sukhatme VP, Kufe DW. Gene therapy targeted by ionizing radiation. Int J Radiat Oncol Biol Phys 1992; 24:565-567.
3. Weichselbaum RR, Hallahan DE, Becktt MA, Mauceri HJ, Lee H, Sukhatme VP, et al. Gene therapy by radiation preferentially radiosensitizes tumor cells. Cancer Res 1994; 54:4266-4269.
4. Hanna NN, Seetharam S, Mauceri HJ, Becktt MA, Jaskowiak NT, Salloum RM, et al. Antitumor interaction of short course endostatin and ionizing radiation. Cancer J 2000; 6:287-293.
5. Takahashi T, Namiki Y, Ohno T. Induction of the suicide HSV-TK gene by activation of the Egr-1 promoter with radioisotopes. Hum Gene Ther 1997; 8:827-833.
6. Griscelli F, Li H, Cheong C, Opolon P, Bennaceu GA, Vassal G, et al. Combined effects of radiotherapy and angiostatin gene therapy in glioma tumor model. Proc Natl Acad Sci USA 2000; 97:6698-6703.
7. Weichselbaum RR, Kufe DW, Advani SJ, Roizman B. Molecular targeting of gene therapy and radiotherapy. Acta Oncol 2001; 40:735-738.
8. Christy B, Nathans D. DNA binding site of the growth factor inducible protein Zif268. Proc Natl Acad Sci USA 1989; 86:8737-8741.
9. Sukhatme VP. Early transcriptional events in cell growth: the Egr family. J Am Soc Nephrol 1990; 1:859-866.
10. Wheldon TE. Radiation physics and genetic targeting: new direction for radiotherapy. The Douglas Lea Lecture 1999. Phys Med Biol 2000; 45:77-95.
11. Scott SD, Marples B, Hendry JH, Lashford LS, Embleton MJ, Hunter RD, et al. A radiation-controlled molecular switch for use in gene therapy of cancer. Gene Ther 2000; 7:1121-1125.
12. Cao XM, Koski RA, Gashler A, McKiernan M, et al. Identification and characterization of the Egr-1 gene product. A DNA-binding zinc finger protein induced by differentiation and growth signal. Mol Cell Biol 1990; 10:1931-1939.
13. Tsai-Morris CH, Cao XM, Sukhatme VP. 5′ flanking and genomic structure of Egr-1, a murine mitogen inducible zinc finger encoding gene. Nucl Acids Res 1988; 16:8835-8846.
14. Datta R, Rubin E, Sukhatme VP, Qureshi S, Hallahan D, Weichselbaum RR, et al. Ionizing radiation activates transcription of EgM gene via CarG elements. Proc Natl Acad Sci USA 1992; 89:10149-10153.
15. Yang Jie. New therapeutic strategy on melanoma. Acta Laser Biol Sin 2003; 12:221-223.
16. Vilcek J, Lee TH. Tumor necrosis factor. New insights into the molecular mechanisms of its multiple actions. J Biol Chem 1991; 25:7313-7316.
17. Rothe J, Gehr G, Loetscher H, Lesslauer W. Tumor necrosis factor receptors - structure and function. Immunol Res 1992; 11:81-90.
18. Wheldon TE, Mairs RJ, Rampling RP, Barrett A. Modelling the enhancement of fractionated radiotherapy by gene transfer to sensitize tumour cells to radiation. Radiother Oncol 1998; 48:5-13.
19. Nemunaitis J, Bohart C, Fong T, Meyer W, Edelman G, Paulson RS, et al. Phase I trial of retroviral vector-mediated interferon (IFN)-gamma gene transfer into autologous tumor cells in patients with metastatic melanoma. Cancer Gene Ther 1998; 5:292-300.
20. Stopeck AT, Jones A, Hersh EM, Thompson JA, Finucane DM, Gutheil JC, et al. Phase II study of direct intralesional gene transfer of allovectin-7, an HLA-B7/beta2-microglobulin DNA-liposome complex, in patients with metastatic melanoma. Clin Cancer Res 2001; 7:2285-2291.