Exhaled nitric oxide levels during acute asthma exacerbation

Academic Emergency Medicine

Volumn 12, Issue 7, 2005, Pages 579-586

  Gill, Michelle ^a,d   Walker, Scott ^a   Khan, Aqeel ^a   Green, Steven M ^a   Kim, Lillian ^b   Gray, Shaun ^b   Krauss, Baruch ^c  

^a Department of Emergency Medicine ^*  (United States)

^b LOMA LINDA UNIVERSITY   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d LOMA LINDA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Asthma exacerbation; Exhaled nitric oxide; Spirometry

Indexed keywords

NITRIC OXIDE;

ACCURACY; ADOLESCENT; ADULT; ARTICLE; ASTHMA; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE EXACERBATION; DISEASE MARKER; DISEASE SEVERITY; EMERGENCY WARD; EXPIRED AIR; FEMALE; HOSPITAL DISCHARGE; HOSPITALIZATION; HUMAN; MALE; MAXIMUM ALLOWABLE CONCENTRATION; PRIORITY JOURNAL; RATING SCALE; RECEIVER OPERATING CHARACTERISTIC; RELAPSE; REPRODUCIBILITY; SAMPLE SIZE; SPIROMETRY;

ACUTE DISEASE; ADOLESCENT; ADULT; ASTHMA; BREATH TESTS; CHILD; CHILD, PRESCHOOL; FEMALE; HOSPITALIZATION; HUMANS; MALE; MIDDLE AGED; NITRIC OXIDE; PROGNOSIS; PROSPECTIVE STUDIES; RECURRENCE; RISK ASSESSMENT; ROC CURVE; SPIROMETRY;

EID: 20444493270     PISSN: 10696563     EISSN: None     Source Type: Journal    
DOI: 10.1197/j.aem.2005.01.018     Document Type: Article

References (44)

1. National Institutes of Health. Asthma statistics. Available at: http://www.nhlbi.nih.gov/health/prof/lung/asthma/asthstat.htm. Accessed Mar 31, 2004.
2. A.B. Becker Challenges to treatment goals and outcomes in pediatric asthma J Allergy Clin Immunol 109 6 Suppl 2002 S533 S538
3. D.P. Skoner Outcome measures in childhood asthma Pediatrics 109 2 Suppl 2002 393 398
4. B.V. Nelson, S. Sears, and J. Woods Expired nitric oxide as a marker for childhood asthma J Pediatr 130 1997 423 427
5. S.L. Jones, J. Kittelson, and J.O. Cowan The predictive value of exhaled nitric oxide measurements in assessing changes in asthma control Am J Respir Crit Care Med 164 2001 738 743
6. N. Kissoon, L.J. Duckworth, K.V. Blake, S.P. Murphy, and J.J. Lima Effect of beta2-agonist treatment on exhaled nitric oxide in healthy children and children with asthma Pediatr Pulmonol 34 2002 203 208
7. B. Gaston Expired nitric oxide in pediatric asthma: emissions testing for children? J Pediatr 131 1997 343 344
8. E. Baraldi, N.M. Azzolin, S. Zanconato, C. Dario, and F. Zacchello Corticosteroids decrease exhaled nitric oxide in children with acute asthma J Pediatr 131 1997 381 385
9. S.A. Kharitonov, and P.J. Barnes Exhaled markers of pulmonary disease Am J Respir Crit Care Med 163 2001 1693 1722
10. L.M. van den Toorn, S.E. Overbeek, J.C. de Jongste, K. Leman, H.C. Hoogsteden, and J.B. Prins Airway inflammation is present during clinical remission of atopic asthma Am J Respir Crit Care Med 164 2001 2107 2113
11. D.N. Payne, I.M. Adcock, N.M. Wilson, T. Oates, M. Scallan, and A. Bush Relationship between exhaled nitric oxide and mucosal eosinophilic inflammation in children with difficult asthma, after treatment with oral prednisolone Am J Respir Crit Care Med 164 2001 1376 1381
12. K. Alving, E. Weitzberg, and J.M. Lundberg Increased amount of nitric oxide in exhaled air of asthmatics Eur Respir J 6 1993 1368 1370
13. J.O. Lundberg, S.L. Nordvall, E. Weitzberg, H. Kollberg, and K. Alving Exhaled nitric oxide in paediatric asthma and cystic fibrosis Arch Dis Child 75 1996 323 326
14. T.L. Frank, A. Adisesh, and A.C. Pickering Relationship between exhaled nitric oxide and childhood asthma Am J Respir Crit Care Med 158 1998 1032 1036
15. S.A. Kharitonov, D.H. Yates, and P.J. Barnes Inhaled glucocorticoids decrease nitric oxide in exhaled air of asthmatic patients Am J Respir Crit Care Med 153 1996 454 457
16. C.M. Salome, A.M. Roberts, N.J. Brown, J. Dermand, G.B. Marks, and A.J. Woolcock Exhaled nitric oxide measurements in a population sample of young adults Am J Respir Crit Care Med 159 1999 911 916
17. S.A. Kharitonov, D.H. Yates, R.A. Robbins, R. Logan-Sinclair, E.A. Shinebourne, and P.J. Barnes Increased nitric oxide in exhaled air of asthmatic patients Lancet 343 1994 133 135
18. P.J. Barnes, and S.A. Kharitonov Exhaled nitric oxide: a new lung function test Thorax 51 1996 233 237
19. P.E. Silkoff, S. Wakita, and J. Chatkin Exhaled nitric oxide after beta2-agonist inhalation and spirometry in asthma Am J Respir Crit Care Med 159 1999 940 944
20. M.J. Lanz, D.Y.M. Leung, and C.W. White Comparison of exhaled nitric oxide to spirometry during emergency treatment of asthma exacerbations with glucocorticoids in children Ann Allergy Asthma Immunol 82 1999 161 164
21. A.F. Massaro, B. Gaston, D. Kita, C. Fanta, J.S. Stamler, and J.M. Drazen Expired nitric oxide levels during treatment of acute asthma Am J Respir Crit Care Med 152 1995 800 803
22. E. Baraldi, C. Dario, and R. Ongaro Exhaled nitric oxide concentrations during treatment of wheezing exacerbation in infants and young children Am J Respir Crit Care Med 159 1999 1284 1288
23. S.E. Crater, E.J. Peters, M.L. Martin, A.W. Murphy, and T.A. Platts-Mills Expired nitric oxide and airway obstruction in asthma patients with an acute exacerbation Am J Respir Crit Care Med 159 1999 806 811
24. Y.G. Tsai, M.Y. Lee, K.D. Yang, D.M. Chu, Y.S. Yuh, and C.H. Hung A single dose of nebulized budesonide decreases exhaled nitric oxide in children with acute asthma J Pediatr 139 2001 433 437
25. Guidelines for the diagnosis and management of asthma. NIH publication no. 91-3042 1991 National Heart, Lung and Blood Institute Bethesda, MD
26. F. Qureshi, J. Pestian, P. Davis, and A. Zaritsky Effect of nebulized ipratropium on the hospitalization rates of children with asthma N Engl J Med 339 1998 1030 1035
27. American Thoracic Society Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma Am Rev Respir Dis 136 1987 225 244
28. S.A. Kharitonov, S.A. Robbins, D.H. Yates, V. Keatings, and P.J. Barnes Acute and chronic effects of cigarette smoking on exhaled nitric oxide Am J Respir Crit Care Med 152 1995 609 612
29. M.G. Person, O. Zetterstrom, V. Argrenius, E. Ihre, and L.E. Gustafsson Single-breath nitric oxide measurements in asthmatic patients and smokers Lancet 343 1994 146 147
30. S.A. Kharitonov, D. Yates, and P.J. Barnes Increased nitric oxide in exhaled air of normal human subjects with upper respiratory infections Eur Respir J 8 1995 295 297
31. Recommendations for standardized procedures for the on-line and off-line measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide in adults and children - 1999 Am J Respir Crit Care Med 160 1999 2104 2117
32. M. Becklake, and R.O. Crapo Lung function testing. Selection of reference values and interpretive strategies Am Rev Respir Dis 144 1991 1202 1218
33. G. Rodrigo, and C. Rodrigo A new index for early prediction of hospitalization in patients with acute asthma Am J Emerg Med 15 1997 8 13
34. B.H. Rowe, G.W. Bota, L. Fabris, S.A. Therrien, R.A. Milner, and J. Jacono Inhaled budesonide in addition to oral corticosteroids to prevent asthma relapse following discharge from the emergency department. A randomized controlled trial JAMA 281 1999 2119 2126
35. K.R. Chapman, P.R. Verbeek, J.G. White, and A.S. Rebuck Effect of a short course of prednisone in the prevention of early relapse after the emergency room treatment of acute asthma N Engl J Med 324 1991 788 794
36. R. Ravel Clinical laboratory medicine. Clinical Application of Laboratory Data, ed 6 1995 Mosby-Year Book, Inc. St. Louis, MO p 2
37. R.C. Strunk, S.J. Szefler, and B.R. Phillips Childhood Asthma Research and Education Network of the National Heart, Lung, and Blood Institute. Relationship of exhaled nitric oxide to clinical and inflammatory markers of persistent asthma in children J Allergy Clin Immunol 112 2003 883 892
38. G.L. Piacentini, A. Bodini, and S. Costella Allergen avoidance is associated with a fall in exhaled nitric oxide in asthmatic children J Allergy Clin Immunol 104 1999 1323 1324
39. R.G. Stirling, S.A. Kharitonov, and D. Campbell for the Asthma and Allergy Group Increase in exhaled nitric oxide levels in patients with difficult asthma and correlation with symptoms and disease severity despite treatment with oral and inhaled corticosteroids Thorax 53 1998 1030 1034
40. L. Brown Heterogeneity, evidence and salt Can J Emerg Med 6 2004 165 166
41. J.M. Sippel, W.E. Holden, and S.A. Tilles Exhaled nitric oxide levels correlate with measures of disease control in asthma J Allergy Clin Immunol 106 2000 645 650
42. G. Berlyne, and N. Barnes No role for NO in asthma? Lancet 355 2000 1029 1030
43. A.C. Olin, A. Aldenbratt, and A. Ekman Increased nitric oxide in exhaled air after intake of a nitrate-rich meal Respir Med 95 2001 153 158
44. C. Bruce, D.H. Yates, and P.S. Thomas Caffeine decreases exhaled nitric oxide Thorax 57 2002 361 363