No effect of polymorphisms in prothrombotic genes on the risk of myocardial infarction in young adults without cardiovascular risk factors [5]

Journal of Thrombosis and Haemostasis

Volumn 3, Issue 1, 2005, Pages 177-179

  Martini, C H ^a   Doggen, C J M ^a   Cavallini, C ^b   Rosendaal, F R ^a   Mannucci, P M ^c  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Hospital of Treviso   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ALPHA2 INTEGRIN; BLOOD CLOTTING FACTOR 5 LEIDEN; BLOOD CLOTTING FACTOR 7; GLYCOPROTEIN IIIA; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTHROMBIN; BETA3 INTEGRIN; BLOOD CLOTTING FACTOR 13; BLOOD CLOTTING FACTOR 5; DNA; FIBRINOGEN; VERY LATE ACTIVATION ANTIGEN 2;

ADULT; ATHEROSCLEROTIC PLAQUE; BLOOD SAMPLING; CARDIOVASCULAR RISK; CONTROLLED STUDY; DIABETES MELLITUS; DNA ISOLATION; FAMILY HISTORY; FEMALE; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; HEART INFARCTION; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; LETTER; MAJOR CLINICAL STUDY; OBESITY; PRIORITY JOURNAL; SMOKING; BODY MASS; CARDIOVASCULAR DISEASE; CASE CONTROL STUDY; FAMILY HEALTH; GENETICS; METABOLISM; RISK; RISK FACTOR; THROMBOCYTE; THROMBOSIS;

BLOOD PLATELETS; BODY MASS INDEX; CARDIOVASCULAR DISEASES; CASE-CONTROL STUDIES; DNA; FACTOR V; FACTOR VII; FACTOR XIII; FAMILY HEALTH; FIBRINOGEN; HUMANS; INTEGRIN ALPHA2BETA1; INTEGRIN BETA3; MYOCARDIAL INFARCTION; ODDS RATIO; PLASMINOGEN ACTIVATOR INHIBITOR 1; POLYMORPHISM, GENETIC; PROTHROMBIN; RISK; RISK FACTORS; THROMBOSIS;

EID: 20444482084     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2004.01080.x     Document Type: Letter

References (7)

1. Atherosclerosis Thrombosis and Vascular Biology Italian Study Group. No evidence of association between prothrombotic gene polymorphisms and the development of acute myocardial infarction at a young age. Circulation 2003; 107: 1117-22.
2. Rosendaal FR, Siscovick DS, Schwartz SM, Beverly RK, Psaty BM, Longstreth WT Jr, Raghunathan TE, Koepsell TD, Reitsma PH. Factor V Leiden (resistance to activated protein C) increases the risk of myocardial infarction in young women. Blood 1997; 89: 2817-21.
3. Rosendaal FR, Siscovick DS, Schwartz SM, Psaty BM, Raghunathan TE, Vos HL. A common prothrombin variant (20210 G to A) increases the risk of myocardial infarction in young women. Blood 1997; 90: 1747-50.
4. Lane DA, Grant PJ. Role of hemostatic gene polymorphisms in venous and arterial thrombotic disease. Blood 2000; 95: 1517-32.
5. Reiner AP, Siscovick DS, Rosendaal FR. Hemostatic risk factors and arterial thrombotic disease. Thromb Haemost 2001; 85: 584-95.
6. Tang Z, Tracy RP. Candidate genes and confirmed genetic polymorphisms associated with cardiovascular disease. J Thromb Thrombol 2001; 11: 49-81.
7. 20210 mutation. Thromb Haemost 1998; 79: 907-11.