Hypoxia recruits a respiratory-related excitatory pathway to brainstem premotor cardiac vagal neurons in animals exposed to prenatal nicotine

Neuroscience

Volumn 133, Issue 4, 2005, Pages 1073-1079

  Evans, C ^a   Wang, J ^b   Neff, R ^c   Mendelowitz, D ^a  

^a GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^b FUDAN UNIVERSITY   (China)

^c NEUROBIOLOGY SECTION   (United States)

Author keywords

Ambiguus; Bradycardia; Cholinergic; Heart rate; Nicotinic; Parasympathetic

Indexed keywords

FLUORESCENT DYE; NICOTINE; TRACER;

AMBIGUUS NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN STEM; BREATHING; CELL ISOLATION; CONTROLLED STUDY; FEMALE; HYPOGLOSSAL NERVE; HYPOXIA; NERVE CELL; NEUROTRANSMISSION; NEWBORN; NONHUMAN; OSMOTIC MINIPUMP; PATCH CLAMP; PRENATAL EXPOSURE; PRIORITY JOURNAL; RAT; RECORDING; RESPIRATORY BURST; SMOKING; SYNAPTIC POTENTIAL; TRANSPLANTATION;

6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ACTION POTENTIALS; ANIMALS; ANIMALS, NEWBORN; ANOXIA; BRAIN STEM; DRUG INTERACTIONS; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; GABA ANTAGONISTS; GLYCINE AGENTS; NEURAL PATHWAYS; NEURONS; NICOTINE; NICOTINIC AGONISTS; PICROTOXIN; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATION; STRYCHNINE; VALINE;

EID: 20444480200     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2005.03.053     Document Type: Article

References (44)

1. R.N. Anderson Deaths leading causes for 2000 National Vital Statistics Reports 50 2002 11
2. G. Anrep, F. Pascual, R. Rossler Respiratory variations of the heart rate. II. The central mechanism of the respiratory sinus arrythmia and the inter-relations between the central and the reflex mechanisms Proc Royal Soc 119 1936 218 232
3. O. Bamford, J. Carroll Dynamic ventilatory responses in rats normal development and effects of prenatal nicotine exposure Respir Physiol 117 1999 29 40
4. E. Bouairi, R. Neff, C. Evans, A. Gold, M.C. Andresen, D. Mendelowitz Respiratory sinus arrhythmia in freely moving and anesthetized rats J Appl Physiol 97 2004 1431 1436
5. M.G. Bulterys, S. Greenland, J.F. Kraus Chronic fetal hypoxia and sudden infant death syndrome interaction between maternal smoking and low hematocrit during pregnancy Pediatrics 86 1990 535 540
6. M.A. Castellini, L.D. Rea, J.L. Sanders, J.M. Castellini, T. Zenteno-Savin Developmental changes in cardiorespiratory patterns of sleep-associated apnea in northern elephant seals Am J Physiol 267 1994 R1294 R1301
7. S.E. Downing, J.C. Lee Laryngeal chemosensitivity a possible mechanism for sudden infant death Pediatrics 55 1975 640 649
8. D.L. Eckberg Human sinus arrhythmia as an index of vagal cardiac outflow J Appl Physiol 54 1983 961 966
9. J.E. Fewell, F.G. Smith, K.Y.N. Vienna Prenatal exposure to nicotine impairs protective responses of rat pups to hypoxia in an age dependent manner Respir Physiol 127 2001 61 73
10. J.E. Fewell, F.G. Smith, V.K. Ng, V.H. Wong, Y. Wang Postnatal age influences the ability of rats to autoresuscitate from hypoxic-induced apnea Am J Physiol Regul Integr Comp Physiol 279 2000 R39 R46
11. S. Garrigue, P. Bordier, P. Jais, D.C. Shah, M. Hocini, C. Raherison, M. Tunon De Lara, M. Haissaguerre, J. Clementy Benefit of atrial pacing in sleep apnea syndrome N Engl J Med 346 2002 404 412
12. G. Gennser, K. Marsal, B. Brantmark Maternal smoking and fetal breathing movements Am J Obstet Gynecol 123 1975 861 867
13. M.P. Gilbey, D. Jordan, D.W. Richter, K.M. Spyer Synaptic mechanisms involved in the inspiratory modulation of vagal cardio-inhibitory neurones in the cat J Physiol 356 1984 65 78
14. W. Grimm, U. Koehler, E. Fus, J. Hoffmann, V. Menz, R. Funck, J.H. Peter, B. Maisch Outcome of patients with sleep apnea-associated severe bradyarrhythmias after continuous positive airway pressure therapy Am J Cardiol 86 A9 2000 688 692
15. B. Haglund, S. Cnattingius Cigarette smoking as a risk factor for sudden infant death syndrome a population-based study Am J Public Health 80 1990 29 32
16. M.B. Harris, W.K. Milsom Parasympathetic influence on heart rate in euthermic and hibernating ground squirrels J Exp Biol 198 Pt 4 1995 931 937
17. M.K. Hathorn Respiratory sinus arrhythmia in new-born infants J Physiol 385 1987 1 12
18. J. Hayano, F. Yasuma, A. Okada, S. Mukai, T. Fujinami Respiratory sinus arrhythmia. A phenomenon improving pulmonary gas exchange and circulatory efficiency Circulation 94 1996 842 847
19. L.M. Hellman, H.L. Johnson, W.E. Tolles, E.H. Jones Some factors affecting the fetal heart rate Am J Obstet Gynecol 82 1961 1055 1063
20. J.A. Hirsch, B. Bishop Respiratory sinus arrhythmia in humans how breathing pattern modulates heart rate Am J Physiol 241 1981 H620 H629
21. C.E. Hunt Sudden infant death syndrome and other causes of infant mortality diagnosis, mechanisms, and risk for recurrence in siblings Am J Respir Crit Care Med 164 2001 346 357
22. D. Jordan, M.E. Khalid, N. Schneiderman, K.M. Spyer The location and properties of preganglionic vagal cardiomotor neurones in the rabbit Pflugers Arch 395 1982 244 250
23. J.C. Lee, B.J. Stoll, S.E. Downing Properties of the laryngeal chemoreflex in neonatal piglets Am J Physiol 233 1977 R30 R36
24. S.P. Lieske, M. Thoby-Brisson, P. Telgkamp, J.M. Ramirez Reconfiguration of the neural network controlling multiple breathing patterns eupnea, sighs and gasps Nat Neurosci 3 2000 600 607
25. A.D. Loewy, K.M. Spyer Central regulation of autonomic functions 1990 Oxford University Press New York
26. R.G. Meny, J.L. Carroll, M.T. Carbone, D.H. Kelly Cardiorespiratory recordings from infants dying suddenly and unexpectedly at home Pediatrics 93 1994 44 49
27. J. Milerad, J. Rajs, E. Gidlund Nicotine and cotinine levels in pericardial fluid in victims of SIDS Acta Paediatr 83 1994 59 62
28. M.M. Myers, W. Fifer, J. Haiken, R.I. Stark Relationships between breathing activity and heart rate in fetal baboons Am J Physiol 258 1990 R1479 R1485
29. D.B. Nachmanoff, A. Panigrahy, J.J. Filiano, F. Mandell, L.A. Sleeper, M. Valdes-Dapena, H.F. Krous, W.F. White, H.C. Kinney Brainstem 3H-nicotine receptor binding in the sudden infant death syndrome J Neuropathol Exp Neurol 57 1998 1018 1025
30. R.A. Neff, S.J. Simmens, C. Evans, D. Mendelowitz Prenatal nicotine exposure alters central cardiorespiratory responses to hypoxia in rats implications for sudden infant death syndrome J Neurosci 24 2004 9261 9268
31. R.A. Neff, J. Wang, S. Baxi, C. Evans, D. Mendelowitz Respiratory sinus arrhythmia endogenous activation of nicotinic receptors mediates respiratory modulation of brainstem cardioinhibitory parasympathetic neurons Circ Res 93 2003 565 572
32. C.F. Poets, R.G. Meny, M.R. Chobanian, R.E. Bonofiglo Gasping and other cardiorespiratory patterns during sudden infant deaths Pediatr Res 45 1999 350 354
33. M.E. Schlaefke Central chemosensitivity a respiratory drive Rev Physiol Biochem Pharmacol 90 1981 171 244
34. J.N. Schuen, O.S. Bamford, J.L. Carroll The cardiorespiratory response to anoxia normal development and the effect of nicotine Respir Physiol 109 1997 231 239
35. T.A. Slotkin Fetal nicotine or cocaine exposure which one is worse? J Pharmacol Exp Ther 285 1998 931 945
36. T.A. Slotkin, J.L. Saleh, E.C. McCook, F.J. Seidler Impaired cardiac function during postnatal hypoxia in rats exposed to nicotine prenatally implications for perinatal morbidity and mortality, and for sudden infant death syndrome Teratology 55 1997 177 184
37. T.A. Slotkin, T.A. Epps, M.L. Stenger, K.J. Sawyer, F.J. Seidler Cholinergic receptors in heart and brainstem of rats exposed to nicotine during development implications for hypoxia tolerance and perinatal mortality Brain Res Dev Brain Res 113 1999 1 12
38. J.C. Smith, H.H. Ellenberger, K. Ballanyi, D.W. Richter, J.L. Feldman Pre-Botzinger complex a brainstem region that may generate respiratory rhythm in mammals Science 254 1991 726 729
39. L.W. Sontag, R.F. Wallace The effect of cigarette smoking during pregnancy upon the fetal heart rate Am J Obstet Gynecol 29 1935 77 83
40. S. Sovik, K. Lossius, L. Walloe Heart rate response to transient chemoreceptor stimulation in term infants is modified by exposure to maternal smoking Pediatr Res 49 2001 558 565
41. W.M. St-John, I.A. Rybak, J.F. Paton Potential switch from eupnea to fictive gasping after blockade of glycine transmission and potassium channels Am J Physiol Regul Integr Comp Physiol 283 2002 R721 R731
42. W.M. St-John, J.C. Leiter Maternal nicotine depresses eupneic ventilation of neonatal rats Neurosci Lett 267 1999 206 208
43. A.G. Tilkian, C. Guilleminault, J.S. Schroeder, K.L. Lehrman, F.B. Simmons, W.C. Dement Sleep-induced apnea syndrome. Prevalence of cardiac arrhythmias and their reversal after tracheostomy Am J Med 63 1977 348 358
44. M.R. Warner, J.M. deTarnowsky, C.C. Whitson, J.M. Loeb Beat-by-beat modulation of AV conduction. II. Autonomic neural mechanisms Am J Physiol 251 1986 H1134 H1142